Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
Penn-Nicholson, A, Hraha, T, Thompson, EG, Sterling, D, Kimbung Mbandi, S, Wall, K, Fisher, M, Suliman, S, Shankar, S, Hanekom, WA, Janjic, N, Hatherill, M, Kaufmann, SH, Sutherland, J, Walzl, G, De Groote, MA and Ochsner, U.
2019.
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
[Online].
PLOS Medicine.
Available from:
https://doi.org/10.1371/journal.pmed.1002781
Penn-Nicholson, A, Hraha, T, Thompson, EG, Sterling, D, Kimbung Mbandi, S, Wall, K, Fisher, M, Suliman, S, Shankar, S, Hanekom, WA, Janjic, N, Hatherill, M, Kaufmann, SH, Sutherland, J, Walzl, G, De Groote, MA and Ochsner, U.
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
[Internet].
PLOS Medicine;
2019.
Available from:
https://doi.org/10.1371/journal.pmed.1002781
Penn-Nicholson, A, Hraha, T, Thompson, EG, Sterling, D, Kimbung Mbandi, S, Wall, K, Fisher, M, Suliman, S, Shankar, S, Hanekom, WA, Janjic, N, Hatherill, M, Kaufmann, SH, Sutherland, J, Walzl, G, De Groote, MA and Ochsner, U
(2019).
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
[Data Collection].
PLOS Medicine.
https://doi.org/10.1371/journal.pmed.1002781
Description
A nonsputum blood test capable of predicting progression of healthy individuals to active tuberculosis (TB) before clinical symptoms manifest would allow targeted treatment to curb transmission. We aimed to develop a proteomic biomarker of risk of TB progression for ultimate translation into a point-of-care diagnostic.
Penn-Nicholson, A, Hraha, T, Thompson, EG, Sterling, D, Kimbung Mbandi, S, Wall, K, Fisher, M, Suliman, S, Shankar, S, Hanekom, WA, Janjic, N, Hatherill, M, Kaufmann, SH, Sutherland, J, Walzl, G, De Groote, MA and Ochsner, U
