Heinz, E, Brindle, R, Morgan-McCalla, A, Peters, K and Thomson, N. 2019. Supporting data for: "Caribbean multi-centre study of Klebsiella pneumoniae: whole-genome sequencing, antimicrobial resistance and virulence factors". [Online]. Figshare. Available from: https://doi.org/10.6084/m9.figshare.7867760.v1
Heinz, E, Brindle, R, Morgan-McCalla, A, Peters, K and Thomson, N. Supporting data for: "Caribbean multi-centre study of Klebsiella pneumoniae: whole-genome sequencing, antimicrobial resistance and virulence factors" [Internet]. Figshare; 2019. Available from: https://doi.org/10.6084/m9.figshare.7867760.v1
Heinz, E, Brindle, R, Morgan-McCalla, A, Peters, K and Thomson, N (2019). Supporting data for: "Caribbean multi-centre study of Klebsiella pneumoniae: whole-genome sequencing, antimicrobial resistance and virulence factors". [Data Collection]. Figshare. https://doi.org/10.6084/m9.figshare.7867760.v1
Description
The surveillance of antimicrobial-resistant isolates has proven to be one of the most valuable tools to understand the global rise of multidrug-resistant bacterial pathogens. We report the first insights into the current situation in the Caribbean, where a pilot project to monitor antimicrobial resistance (AMR) through phenotypic resistance measurements combined with whole-genome sequencing was set up in collaboration with the Caribbean Public Health Agency (CARPHA). Our first study focused on Klebsiella pneumoniae , a highly relevant organism amongst the Gram-negative opportunistic pathogens worldwide causing hospital- and community-acquired infections. Our results show that not only carbapenem resistance, but also hypervirulent strains, are circulating in patients in the Caribbean. Our current data does not allow us to infer their prevalence in the population. We argue for the urgent need to further support AMR surveillance and stewardship in this almost uncharted territory, which can make a significant impact on the reduction of antimicrobial usage.
Data capture method | Experiment |
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Date (Date published in a 3rd party system) | 1 May 2019 |
Language(s) of written materials | English |
Data Creators | Heinz, E, Brindle, R, Morgan-McCalla, A, Peters, K and Thomson, N |
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LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection |
Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
Funders |
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Date Deposited | 23 Jul 2019 12:26 |
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Last Modified | 08 Jul 2021 12:52 |
Publisher | Figshare |