Additional file 1: of A genomic atlas of systemic interindividual epigenetic variation in humans
Gunasekara, CJ, Scott, CA, Laritsky, E, Baker, MS, MacKay, H, Duryea, JD, Kessler, NJ
, Hellenthal, H, Wood, AC, Hodges, KR, Gandhi, M, Hair, AB, Silver, M, Moore, SE, Prentice, AM, Li, Y, Chen, R, Coarfa, C and Waterland, RA
(2019).
Additional file 1: of A genomic atlas of systemic interindividual epigenetic variation in humans.
[Dataset].
Figshare.
https://doi.org/10.6084/m9.figshare.8217572.v1
, Hellenthal, H, Wood, AC, Hodges, KR, Gandhi, M, Hair, AB, Silver, M, Moore, SE, Prentice, AM, Li, Y, Chen, R, Coarfa, C and Waterland, RA
(2019).
Additional file 1: of A genomic atlas of systemic interindividual epigenetic variation in humans.
[Dataset].
Figshare.
https://doi.org/10.6084/m9.figshare.8217572.v1
DNA methylation is thought to be an important determinant of human phenotypic variation, but its inherent cell type specificity has impeded progress on this question. At exceptional genomic regions, interindividual variation in DNA methylation occurs systemically. Like genetic variants, systemic interindividual epigenetic variants are stable, can influence phenotype, and can be assessed in any easily biopsiable DNA sample. We describe an unbiased screen for human genomic regions at which interindividual variation in DNA methylation is not tissue-specific.
Keywords
Supplementary, genomic atlas, variation, Additional, interindividual| Item Type | Dataset |
|---|---|
| Capture method | Experiment |
| Date | 3 June 2019 |
| Language(s) of written materials | English |
| Creator(s) |
Gunasekara, CJ, Scott, CA, Laritsky, E, Baker, MS, MacKay, H, Duryea, JD, Kessler, NJ, Hellenthal, H, Wood, AC, Hodges, KR, Gandhi, M, Hair, AB, Silver, M, Moore, SE, Prentice, AM, Li, Y, Chen, R, Coarfa, C and Waterland, RA
|
| LSHTM Faculty/Department | MRC Unit The Gambia at LSHTM |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI UNSPECIFIED 1R01DK111522 http://dx.doi.org/10.13039/100000062 |
| Date Deposited | 22 Jul 2019 13:25 |
| Last Modified | 15 Nov 2021 10:05 |
| Publisher | Figshare |
No files available. Please consult associated links.
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