Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands

Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch. 2016. Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands. [Online]. Figshare. Available from: https://doi.org/10.1371/journal.pntd.0004863.

Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch. Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands. [Internet] LSHTM Data Compass. Figshare; 2016. Available from: https://doi.org/10.1371/journal.pntd.0004863.

Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch (2016). Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands. [Data Collection]. Figshare. https://doi.org/10.1371/journal.pntd.0004863.

Description

Description of data capture We conducted a population-based trachoma prevalence survey of 3674 individuals from two Solomon Islands provinces. Participants were examined for clinical signs of trachoma. Conjunctival swabs were collected from all children aged 1–9 years. We tested swabs for Chlamydia trachomatis (Ct) DNA using droplet digital PCR. Chlamydial DNA from positive swabs was enriched and sequenced for use in phylogenetic analysis.
Data capture method Experiment
Data Collection Period
FromTo
October 2013November 2013
Date (Published in a 3rd party system) 7 September 2016
Geographical area covered
North LatitudeEast LongitudeSouth LatitudeWest Longitude
-9.18141160.823-10.1237159.472
Language(s) of written materials English
Data Creators Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch
LSHTM Faculty/Department Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom, Solomon Islands Ministry of Health and Medical Services, Honiara, Solomon Islands, University College London Hospitals, London, United Kingdom, Lata Hospital, Lata, Santa Cruz, Solomon Islands, Bellona Rural Health Centre, Bellona, Solomon Islands, University College London, London, United Kingdom, Task Force for Global Health, Decatur, Georgia, United States of America, Royal Victorian Eye and Ear Hospital, Melbourne, Australia, University of Melbourne, Melbourne, Australia
Funders
ProjectFunderGrant NumberFunder URI
UNSPECIFIEDWellcome Trust098521/B/12/ZUNSPECIFIED
UNSPECIFIEDDepartment for International DevelopmentUNSPECIFIEDUNSPECIFIED
Depositor LSHTM Library & Archives Service
Date Deposited 04 Oct 2016 12:14
Last Modified 17 Jan 2019 22:51
Publisher Figshare

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Data Visualisation

Filename: S1_Figure.png

Description: Maximum likelihood phylogram of (A) genome and (B) plasmid sequences from clinical specimens assembled using C. trachomatis E/Bour reference. All branches had bootstrap values over 85/100

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Description: Phylogram illustrating relationship of Solomon Islands sequences to reference sequences at (A) ompA, (B) trpA and (C) PZ regions

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Description: This manuscript adheres to the STROBE guidelines

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Description: Sequence accession numbers

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