Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil
; Nicholls, SM; Tanuri, A; Rossi, ÁD; Braga, CK; Gerber, AL; de C. Guimarães, AP; Gaburo, N; Alencar, CS; Ferreira, AC; Lima, CX; Levi, JE; Granato, C; Ferreira, GM; Francisco, RS; Granja, F; Garcia, MT; Moretti, ML; Perroud, MW; Castiñeiras, Terezinha M. P. P.; Lazari, CS; Hill, SC; de Souza Santos, AA; Simeoni, CL; Forato, J; Sposito, AC; Schreiber, AZ; Santos, MNN; de Sá, CZ; Souza, RP; Resende-Moreira, LC; Teixeira, MM; Hubner, J; Leme, PAF; Moreira, RG; Nogueira, ML; Ferguson, NM; Costa, SF; Proenca-Modena, JL; Vasconcelos, ATR; Bhatt, S; Lemey, P; Wu, C; Rambaut, A; Loman, NJ; Aguiar, RS; Pybus, OG; Sabino, EC and Faria, NR
(2020).
Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil.
[Dataset].
Dryad.
http://doi.org/10.5061/dryad.rxwdbrv5z
Brazil currently has one of the fastest growing SARS-CoV-2 epidemics in the world. Owing to limited available data, assessments of the impact of non-pharmaceutical interventions (NPIs) on virus spread remain challenging. Using a mobility-driven transmission model, we show that NPIs reduced the reproduction number from >3 to 1–1.6 in São Paulo and Rio de Janeiro. Sequencing of 427 new genomes and analysis of a geographically representative genomic dataset identified >100 international virus introductions in Brazil. We estimate that most (76%) of the Brazilian strains fell in three clades that were introduced from Europe between 22 February11 March 2020. During the early epidemic phase, we found that SARS-CoV-2 spread mostly locally and within-state borders. After this period, despite sharp decreases in air travel, we estimated multiple exportations from large urban centers that coincided with a 25% increase in average travelled distances in national flights. This study sheds new light on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil, and provide evidence that current interventions remain insufficient to keep virus transmission under control in the country.
Keywords
SARS-CoV-2; COVID-19; Coronavirus; Non-pharmaceutical interventions| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Unknown |
| Date | 5 August 2020 |
| Language(s) of written materials | English |
| Creator(s) |
Candido, DS; Claro, IM; de Jesus, JG; Souza, WM; Moreira, FRR; Dellicour, S; Mellan, TA; du Plessis, L; Pereira, RHM; Sales, FCS; Manuli, ER; Thézé, J; Almeida, L; Menezes, MT; Voloch, CM; Fumagalli, MJ; Coletti, TM; da Silva, CAM; Ramundo, MS; Amorim, MR; Hoeltgebaum, HH; Mishra, S; Gill, MS; Carvalho, LM; Buss, LF; Prete, CA; Ashworth, J; Nakaya, HI; Peixoto, PS; Brady, OJ; Nicholls, SM; Tanuri, A; Rossi, ÁD; Braga, CK; Gerber, AL; de C. Guimarães, AP; Gaburo, N; Alencar, CS; Ferreira, AC; Lima, CX; Levi, JE; Granato, C; Ferreira, GM; Francisco, RS; Granja, F; Garcia, MT; Moretti, ML; Perroud, MW; Castiñeiras, Terezinha M. P. P.; Lazari, CS; Hill, SC; de Souza Santos, AA; Simeoni, CL; Forato, J; Sposito, AC; Schreiber, AZ; Santos, MNN; de Sá, CZ; Souza, RP; Resende-Moreira, LC; Teixeira, MM; Hubner, J; Leme, PAF; Moreira, RG; Nogueira, ML; Ferguson, NM; Costa, SF; Proenca-Modena, JL; Vasconcelos, ATR; Bhatt, S; Lemey, P; Wu, C; Rambaut, A; Loman, NJ; Aguiar, RS; Pybus, OG; Sabino, EC and Faria, NR
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 24 Aug 2020 13:10 |
| Last Modified | 08 Jul 2021 12:49 |
| Publisher | Dryad |
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