XPHACTOR Clinical Score dataset

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Hanifa, Y, Fielding, K, Grant, AD and Churchyard, GJ. 2016. XPHACTOR Clinical Score dataset. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: 10.17037/DATA.204

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The World Health Organization (WHO) recommendation for regular tuberculosis (TB) screening of HIV-positive individuals with Xpert MTB/RIF as the first diagnostic test has major resource implications. The aim of our study was to develop a score, comprising elements readily available in primary care, to predict probability of TB in adults attending for routine HIV care screened for TB and found WHO tool positive. We used data collected for “Xpert for people attending HIV/AIDS care: test or review?” (XPHACTOR), a prospective cohort study evaluating a risk-based algorithm to prioritise Xpert MTB/RIF testing amongst adults attending for routine HIV care in South Africa, to develop and validate our clinical score. This dataset contains data for 1,048 HIV-positive adults attending for routine HIV care and reporting ≥1 symptom on the WHO screening tool. The dataset is split 50:50 to derive, and internally validate the prediction model. It includes basic demographics, TB diagnoses, and candidate predictors considered for the score. Data was collected for the purpose of HIV and TB research and can only be reused for related research, in accordance with the participant consent agreement.

Completed Date: August 2016
Data capture method:
Mode of data capture
Interview: Face-to-face
Questionnaire: Fixed form - Paper
Data Creators(s): Hanifa, Y, Fielding, K, Grant, AD and Churchyard, GJ
Associated roles: Grant, AD (Principal Investigator), Churchyard, GJ (Principal Investigator), Chihota, V (Co-Investigator), Ndlovu, N (Project Manager), Charalambous, S (Co-Investigator), Stevens, W (Co-Investigator), Nicol, M (Co-Investigator), Karstaedt, A (Co-Investigator), Sahid, F (Other), Adonis, L (Co-Investigator), McCarthy, K (Co-Investigator), Foster, N (Co-Investigator), Sinanovic, E (Co-Investigator) and Vassall, A (Co-Investigator)
LSHTM Faculty/Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Faculty of Public Health and Policy > Dept of Global Health and Development
Research Centre: TB Centre
Participating Institutions: London School of Hygiene & Tropical Medicine, London, United Kingdom, The Aurum Institute, South Africa, National Health Laboratory Services, South Africa, University of Cape Town, South Africa
Part of study:


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