Data from: Health services intervention integrating HTN and HIV care improves long-term blood pressure control among people living with HIV in Uganda

Okello, E, Atukunda, M, Balzer, LB

, Arinitwe, E, Twinamtsiko, B, Ayebare, M, Tindimwebwa, W, Nangendo, J, Kayima, J, Mutungi, G, Kapiga, S

, Charlebois, ED, Kamya, MR, Grosskurth, H

and Kabami, J (2025). Data from: Health services intervention integrating HTN and HIV care improves long-term blood pressure control among people living with HIV in Uganda. [Dataset]. Dryad.

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Data to support the analyses conducted in “Health services intervention integrating HTN and HIV care improves long-term blood pressure control among people living with HIV in Uganda” by Dr. Okello et al. The dataset contains the sex, age group, health center level, and hypertension stage over time (0, 3, 6, 9, 12 months) of 1200 persons with HIV from Uganda.

Keywords

HIV; Hypertension; Medical and health sciences; longitudinal

Item Type	Dataset
Resource Type	Resource Type Resource Description Dataset Quantitative
Description of data capture	Globally, the prevalence of hypertension (HTN) among people with HIV (PWH) has increased dramatically over the last decade. In a cluster randomized trial, we evaluated the effect of a multicomponent intervention model on blood pressure (BP) control among PWH in rural Uganda. The integrated HIV/HTN trial enrolled adults (≥18-years) with HIV from 52 health centres in 26 districts of rural Southwestern Uganda. The intervention included: 1) health-worker training on integrating HTN care into HIV services, 2) promoting HTN screening and treatment among providers; 3) availing essential equipment and consumables; and 4) WhatsApp messaging for coordination. Among intervention participants with previously diagnosed HTN (defined as BP measurement >140/90mmHg), we evaluated longitudinal changes in the proportion with World Health Organization (WHO) defined control (<140/90mmHg) from trial baseline to 12-months of follow-up. We further reported the proportions that achieved BP reduction by ≥10mmHg. Of the 1200 intervention participants with HTN, 60% were female, with a median age of 49 years. At trial baseline, only 3.6% of participants had controlled BP. After 12 months of the intervention, 36.7% had achieved control, corresponding to an absolute increase of 33.1% (95%CI: 25.3-41.0%; p<0.001). Significant improvements in BP control were observed across subgroups of age, sex and level of health centre. In addition, after 12 months, 70% of all participants had achieved at least 10mmHg reduction in their BP, including 74% of participants with baseline Grade 2 HTN (160-179/100-109 mmHg) and 79% of participants with Grade 3 HTN (≥180/110 mmHg). Among participants without WHO-level control at 12-months, 54% achieved at least 10mmHg reduction in BP. This health services intervention to integrate HTN and HIV care in rural primary care facilities improved long-term BP control by 30% and most participants with baseline Grade 2 and 3 HTN achieved >10mmHg reduction in their BP over the 12-month follow-up.
Capture method	Measurements and tests
Date	6 August 2025
Language(s) of written materials	English
Creator(s)	Okello, E, Atukunda, M, Balzer, LB, Arinitwe, E, Twinamtsiko, B, Ayebare, M, Tindimwebwa, W, Nangendo, J, Kayima, J, Mutungi, G, Kapiga, S , Charlebois, ED, Kamya, MR, Grosskurth, H and Kabami, J
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology & International Health (2023-)
Participating Institutions	Uganda Heart Institute, Kampala, Uganda; Infectious Diseases Research Collaboration; University of California, Berkeley, California; Makerere University, Kampala, Uganda; Ministry of Health; Mwanza Intervention Trials Unit, Mwanza, Tanzania; London School of Hygiene & Tropical Medicine, London, United Kingdom; University of California San Francisco Medical Center; Kabale University, Kabale, Uganda
Funders	Project Funder Grant Number Funder URI Leveraging the HIV Platform for Hypertension Control in Uganda Horizon 2020 Framework Programme CSA2018HS2518 https://doi.org/10.13039/100010661
Date Deposited	07 Aug 2025 08:54
Last Modified	07 Aug 2025 08:54
Publisher	Dryad