Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria
(2017).
Whole-genome sequencing illuminates the evolution and spread of multidrug-resistant tuberculosis in Southwest Nigeria.
[Dataset].
PLOS ONE.
https://doi.org/10.1371/journal.pone.0184510.s001
This dataset consists of two files: (1) a spreadsheet containing Isolates metadata that covers study site, age, sex, treatment status (study case), HIV status, MDR & pre-XDR status, as well as lineage information inferred from kvarq, phyressse (Phy) and TBProfiler (tbp); and (2) a spreadsheet that contains phenotypic resistance profiles to first line drugs (rifampicin, isoniazid, streptomycin and ethambutol) for all isolates and to second line drugs (capreomycin, fluoroquinolone, ethionamide and amikacin) for MDR isolates. Table also lists presence of known resistance mutations as detected by the three resistance prediction tools kvarq, phyrese and tbprofiler.
Keywords
MDR-TB, multidrug-resistant tuberculosis, Whole-genome sequencing, Cameroon clade, multi-drug resistance, Southwest Nigeria, Nigeria| Item Type | Dataset |
|---|---|
| Capture method | Unknown |
| Date | 20 September 2017 |
| Language(s) of written materials | English |
| Creator(s) |
Senghore, M, Otu, J, Witney, A, Gehre, F, Doughty, EL, Kay, GL, Butcher, P, Salako, K, Kehinde, A, Onyejepu, N, Idigbe, E, Corrah, T, de Jong, B, Pallen, MJ and Antonio, M
|
| LSHTM Faculty/Department | MRC Unit The Gambia at LSHTM |
| Participating Institutions | MRC Unit The Gambia at LSHTM, Fajara, Banjul, The Gambia |
| Date Deposited | 27 Nov 2024 16:10 |
| Last Modified | 27 Nov 2024 16:10 |
| Publisher | PLOS ONE |
No files available. Please consult associated links.
