The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data

Kim, ES, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL. 2023. The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data. [Online]. PLOS Neglected Tropical Diseases. Available from: https://doi.org/10.1371/journal.pntd.0011439.s006

Kim, ES, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL. The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data [Internet]. PLOS Neglected Tropical Diseases; 2023. Available from: https://doi.org/10.1371/journal.pntd.0011439.s006

Kim, ES, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL (2023). The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data. [Data Collection]. PLOS Neglected Tropical Diseases. https://doi.org/10.1371/journal.pntd.0011439.s006

Description

Mass Drug Administration (MDA) is the main strategy for control of soil-transmitted helminth (STH) infections, with single-dose benzimidazole (albendazole or mebendazole) the principal MDA option. In Mayuge district, Uganda, an MDA programme has been in place for over fifteen years but hookworm infection remains common and there is concern that the effectiveness of single-dose albendazole as currently used for MDA may be sub-optimal. This study aims to assess the efficacy of dual- versus single-dose albendazole, with and without fatty food co-administration against hookworm, the dominant form of STHs in Mayuge district, Uganda.

Methods

Data capture method	Unknown
Date (Date published in a 3rd party system)	3 July 2023
Language(s) of written materials	English

People & Groups

Data Creators	Kim, ES, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom, World Vision Korea, Seoul, Korea, Ministry of Health, Kampala, Uganda, Save the Children International, Moroto, Uganda, Kotido district local government, Kotido, Uganda