The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data
Kim, ES
, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL
(2023).
The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data.
[Data Collection].
PLOS Neglected Tropical Diseases.
https://doi.org/10.1371/journal.pntd.0011439.s006
, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL
(2023).
The impact of dual- versus single-dosing and fatty food co-administration on albendazole efficacy against hookworm among children in Mayuge district, Uganda: Results from a 2x2 factorial randomised controlled trial. S1 Data.
[Data Collection].
PLOS Neglected Tropical Diseases.
https://doi.org/10.1371/journal.pntd.0011439.s006
Mass Drug Administration (MDA) is the main strategy for control of soil-transmitted helminth (STH) infections, with single-dose benzimidazole (albendazole or mebendazole) the principal MDA option. In Mayuge district, Uganda, an MDA programme has been in place for over fifteen years but hookworm infection remains common and there is concern that the effectiveness of single-dose albendazole as currently used for MDA may be sub-optimal. This study aims to assess the efficacy of dual- versus single-dose albendazole, with and without fatty food co-administration against hookworm, the dominant form of STHs in Mayuge district, Uganda.
Keywords
Hookworms, Helminth infections, Soil-transmitted helminthiases, Drug administration, Eggs, Schools, Uganda, Drug therapy| Item Type | Data Collection |
|---|---|
| Capture method | Unknown |
| Date | 3 July 2023 |
| Language(s) of written materials | English |
| Creator(s) |
Kim, ES, Adriko, M, Aidah, W, Oseku, KC, Lokure, D, Sabapathy, K and Webb, EL
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom, World Vision Korea, Seoul, Korea, Ministry of Health, Kampala, Uganda, Save the Children International, Moroto, Uganda, Kotido district local government, Kotido, Uganda |
| Date Deposited | 09 Nov 2023 12:03 |
| Last Modified | 09 Nov 2023 12:03 |
| Publisher | PLOS Neglected Tropical Diseases |
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