Additional file 1 of Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study
and Richmond, RC
(2022).
Additional file 1 of Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study.
[Dataset].
Figshare.
https://doi.org/10.6084/m9.figshare.21303008.v1
Additional file 1. S1. Exposure instruments to proxy hormone levels in the overall breast cancer incidence MR analysis. S2. The strength of the instruments for each hormone including the variance explained and the F statistic. S3. Hormone and breast cancer incidence associations using the alternative MR methods: MR Egger, weighted median, weighted mode and MR-RAPS. S4. MR intercept calculations to identify evidence of pleiotropy. S5. Genetic correlation results between hormones. S6. Exposure instruments to proxy hormone levels in the subtype specific MR analysis. S7. Exposure instruments to proxy hormone levels in the BRCA1 mutated TNBC MR analysis. S8. Power calculations for each hormone and overall and subtype specific BC analysis.
Keywords
Sex steroid hormones; Breast cancer; Mendelian randomization| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Measurements and tests |
| Date | 10 October 2022 |
| Language(s) of written materials | English |
| Creator(s) |
Nounu, A; Kar, SP; Relton, CL and Richmond, RC
|
| LSHTM Faculty/Department | Academic Services & Administration > Directorate |
| Participating Institutions | University of Bristol, Bristol, United Kingdom |
| Date Deposited | 03 Aug 2023 14:54 |
| Last Modified | 18 Sep 2025 14:36 |
| Publisher | Figshare |
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