Nounu, A, Kar, SP, Relton, CL and Richmond, RC. 2022. Additional file 1 of Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study. [Online]. Figshare. Available from: https://doi.org/10.6084/m9.figshare.21303008.v1
Nounu, A, Kar, SP, Relton, CL and Richmond, RC. Additional file 1 of Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study [Internet]. Figshare; 2022. Available from: https://doi.org/10.6084/m9.figshare.21303008.v1
Nounu, A, Kar, SP, Relton, CL and Richmond, RC (2022). Additional file 1 of Sex steroid hormones and risk of breast cancer: a two-sample Mendelian randomization study. [Data Collection]. Figshare. https://doi.org/10.6084/m9.figshare.21303008.v1
Description
Additional file 1. S1. Exposure instruments to proxy hormone levels in the overall breast cancer incidence MR analysis. S2. The strength of the instruments for each hormone including the variance explained and the F statistic. S3. Hormone and breast cancer incidence associations using the alternative MR methods: MR Egger, weighted median, weighted mode and MR-RAPS. S4. MR intercept calculations to identify evidence of pleiotropy. S5. Genetic correlation results between hormones. S6. Exposure instruments to proxy hormone levels in the subtype specific MR analysis. S7. Exposure instruments to proxy hormone levels in the BRCA1 mutated TNBC MR analysis. S8. Power calculations for each hormone and overall and subtype specific BC analysis.
| Data capture method | Measurements and tests |
|---|---|
| Date (Date published in a 3rd party system) | 10 October 2022 |
| Language(s) of written materials | English |
| Data Creators | Nounu, A, Kar, SP, Relton, CL and Richmond, RC |
|---|---|
| LSHTM Faculty/Department | Academic Services & Administration > Directorate |
| Participating Institutions | University of Bristol, Bristol, United Kingdom |
| Date Deposited | 03 Aug 2023 14:54 |
|---|---|
| Last Modified | 03 Aug 2023 14:54 |
| Publisher | Figshare |
