Kibirige, D, Sekitoleko, I, Balungi, P, Kyosiimire-Lugemwa, J, Lumu, W, Jones, AG, Hattersley, AT, Smeeth, L and Nyirenda, MJ. 2022. Islet autoantibody positivity in an adult population with recently diagnosed diabetes in Uganda. S1 Data. [Online]. PLOS ONE. Available from: https://doi.org/10.1371/journal.pone.0268783.s001
Kibirige, D, Sekitoleko, I, Balungi, P, Kyosiimire-Lugemwa, J, Lumu, W, Jones, AG, Hattersley, AT, Smeeth, L and Nyirenda, MJ. Islet autoantibody positivity in an adult population with recently diagnosed diabetes in Uganda. S1 Data [Internet]. PLOS ONE; 2022. Available from: https://doi.org/10.1371/journal.pone.0268783.s001
Kibirige, D, Sekitoleko, I, Balungi, P, Kyosiimire-Lugemwa, J, Lumu, W, Jones, AG, Hattersley, AT, Smeeth, L and Nyirenda, MJ (2022). Islet autoantibody positivity in an adult population with recently diagnosed diabetes in Uganda. S1 Data. [Data Collection]. PLOS ONE. https://doi.org/10.1371/journal.pone.0268783.s001
Description
Aims:
This study aimed to investigate the frequency of islet autoantibody positivity in adult patients with recently diagnosed diabetes in Uganda and its associated characteristics.
Methods:
Autoantibodies to glutamic acid decarboxylase-65 (GADA), zinc transporter 8 (ZnT8-A), and tyrosine phosphatase (IA-2A) were measured in 534 adult patients with recently diagnosed diabetes. Islet autoantibody positivity was defined based on diagnostic thresholds derived from a local adult population without diabetes. The socio-demographic, clinical, and metabolic characteristics of islet autoantibody-positive and negative participants were then compared. The differences in these characteristics were analysed using the x2 test for categorical data and the Kruskal Wallis test for continuous data. Multivariate analysis was performed to identify predictors of islet autoantibody positivity.
| Data capture method | Measurements and tests | ||||||||
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| Date (Date published in a 3rd party system) | 23 May 2022 | ||||||||
| Geographical area covered (offline during plugin upgrade) |
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| Language(s) of written materials | English |
| Data Creators | Kibirige, D, Sekitoleko, I, Balungi, P, Kyosiimire-Lugemwa, J, Lumu, W, Jones, AG, Hattersley, AT, Smeeth, L and Nyirenda, MJ |
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| LSHTM Faculty/Department | Academic Services & Administration > Directorate Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Date Deposited | 15 Jul 2022 08:51 |
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| Last Modified | 15 Jul 2022 08:51 |
| Publisher | PLOS ONE |
