Combined HIV Adolescent Prevention Study (CHAPS)

Webb, E. 2022. Combined HIV Adolescent Prevention Study (CHAPS). [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00002891.

Webb, E. Combined HIV Adolescent Prevention Study (CHAPS) [Internet]. London School of Hygiene & Tropical Medicine; 2022. Available from: https://doi.org/10.17037/DATA.00002891.

Webb, E (2022). Combined HIV Adolescent Prevention Study (CHAPS). [Project]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00002891.

Description

CHAPS was a a mixed-methods study amongst young people aged 13–24 years. The first component consists of qualitative research to identify the barriers and motivators towards the uptake of PrEP amongst young people in South Africa, Uganda and Zimbabwe. The second component is a randomised clinical trial (ClinicalTrials.gov NCT03986970) using a novel ex vivo HIV challenge method to investigate the optimal PrEP treatment (FTC-TDF vs FTC-TAF), dose and schedule.

Project

Project start and completion date

From	To
2017	2022

Language(s) of written materials

English

People & Groups

Data Creators	Webb, E
Project contact	Webb, Emily
Associated roles	Fox, J (Principal Investigator)
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom, King's College London, London, United Kingdom, University of the Witwatersrand, Johannesburg, South Africa, University of Cape Town, Cape Town, South Africa, Harare, Zimbabwe, University of Zimbabwe, Harare, Zimbabwe, Imperial College London, London, United Kingdom, University of Liverpool, Liverpool, United Kingdom, Karolinska Institutet, Solna, Sweden, Desmond Tutu HIV Foundation, Cape Town, South Africa, University of Washington, Seattle, Washington, United States of America