The conjunctival transcriptome in Ethiopians after trichiasis surgery: associations with the development of eyelid contour abnormalities and the effect of oral doxycycline treatment

London School of Hygiene & Tropical Medicine (2019). The conjunctival transcriptome in Ethiopians after trichiasis surgery: associations with the development of eyelid contour abnormalities and the effect of oral doxycycline treatment. [Dataset]. NCBI Gene Expression Omnibus. https://identifiers.org/geo:GSE135455
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Surgery to correct trichiasis is a key component of the WHO trachoma control strategy, however unfavourable outcomes such as eyelid contour abnormalities (ECA) following surgery are relatively common. This study aimed to understand the transcriptional changes associated with the early development of ECA and the impact of doxycycline, which has anti-inflammatory and anti-fibrotic properties, upon these transcription patterns.

Keywords

Trichiasis; Conjunctiva; Eyelid contour abnormalities; Post-operative; Scarring; Inflammation; Doxycycline

Item Type Dataset
Resource Type
Resource Type
Resource Description
Dataset
Quantitative
Capture method Unknown
Date 21 August 2019
Language(s) of written materials English
Creator(s) London School of Hygiene & Tropical Medicine
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom
Date Deposited 30 Sep 2021 08:52
Last Modified 20 Jan 2026 14:34
Publisher NCBI Gene Expression Omnibus

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