Strachan, D, Pearce, N and Garcia-Marcos, L. 2017. International Study of Asthma and Allergies in Childhood, 1992-2005. [Online]. UK Data Service. Available from: http://doi.org/10.5255/UKDA-SN-8131-1
Strachan, D, Pearce, N and Garcia-Marcos, L. International Study of Asthma and Allergies in Childhood, 1992-2005 [Internet]. UK Data Service; 2017. Available from: http://doi.org/10.5255/UKDA-SN-8131-1
Strachan, D, Pearce, N and Garcia-Marcos, L (2017). International Study of Asthma and Allergies in Childhood, 1992-2005. [Data Collection]. UK Data Service. http://doi.org/10.5255/UKDA-SN-8131-1
Alternative Title
SAAC
Description
The International Study of Asthma and Allergies in Childhood (ISAAC) was a worldwide epidemiological research programme established in 1991 to investigate asthma, rhinoconjunctivitis and eczema in children, due to considerable concern that these conditions were increasing in many countries, and that the causes of this increase were unknown. ISAAC Phase One was an international multi-centre cross-sectional study involving two age groups of school children, 13-14 year olds (adolescents) and 6-7 year olds (children). Schools were randomly selected from a defined geographical area. Written questionnaires on asthma, rhinitis and eczema symptoms (translated from English) were completed by the adolescents at school, and at home by the parents of the children. An asthma symptoms video questionnaire for the adolescents was optional. ISAAC Phase Two involved more intensive studies in a smaller number of selected centres. Children aged 8-12 years were examined for flexural dermatitis, underwent skin prick tests for atopy, bronchial responsiveness to hypertonic saline, blood sampling and storage for serum IgE and genetic analyses, and additional questionnaires were completed by their parents. ISAAC Phase Three, a repeat of Phase One after at least five years, examined variations in time trends of childhood asthma, rhinoconjunctivitis and eczema around the world, and expanded the world maps of these conditions. Additional questions on risk factors were included in Phase Three. The ISAAC programme grew to involve nearly 2 million children from 306 study centres in 105 countries, before it formally closed in December 2012.
Data capture method | Questionnaire, Lab observation: Participant | ||||
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Data Collection Period |
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Date (Date published in a 3rd party system) | 22 February 2017 | ||||
Language(s) of written materials | English |
Data Creators | Strachan, D, Pearce, N and Garcia-Marcos, L |
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LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Medical Statistics |
Participating Institutions | University of London, London, United Kingdom, London School of Hygiene & Tropical Medicine, London, United Kingdom, University of Murcia, Murcia, Spain, University of Auckland, Auckland, New Zealand |
Date Deposited | 22 Sep 2021 16:04 |
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Last Modified | 26 Nov 2021 11:08 |
Publisher | UK Data Service |