Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes

Muthui, MK, Takashima, E, Omondi, BR, Kinya, C, Muasya, WI, Nagaoka, H, Mwai, K, Orindi, B, Wambua, J, Bousema, T, Drakeley, C, Blagborough, AM, Marsh, K, Bejon, P and Kapulu, MC. 2021. Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes. [Online]. Harvard Dataverse. Available from: https://doi.org/10.7910/DVN/WL8TRW

Muthui, MK, Takashima, E, Omondi, BR, Kinya, C, Muasya, WI, Nagaoka, H, Mwai, K, Orindi, B, Wambua, J, Bousema, T, Drakeley, C, Blagborough, AM, Marsh, K, Bejon, P and Kapulu, MC. Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes [Internet]. Harvard Dataverse; 2021. Available from: https://doi.org/10.7910/DVN/WL8TRW

Muthui, MK, Takashima, E, Omondi, BR, Kinya, C, Muasya, WI, Nagaoka, H, Mwai, K, Orindi, B, Wambua, J, Bousema, T, Drakeley, C, Blagborough, AM, Marsh, K, Bejon, P and Kapulu, MC (2021). Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes. [Data Collection]. Harvard Dataverse. https://doi.org/10.7910/DVN/WL8TRW

Description

We used data from a longitudinally monitored cohort of children and adults from Kilifi county located along the Kenyan coast collected between 1998-2016 to describe the factors associated with the acquisition of antibody responses to antigens expressed on the surface of mature gametocytes. A panel of candidate gametocyte antigens were identified and produced as recombinant protein for this analysis. The datasets comprise data from cross-sectional surveys carried out to assess parasite prevalence. The datasets were used to carry out analyses aimed at describing the seroprevalence of antibodies to the candidate antigens, and assess the factors associated with antibody responses to these antigens. The overall aim of the analyses was to improve our understanding of immunity to the transmissible stages of the malaria parasite.

Methods

Data capture method

Questionnaire

Date (Date published in a 3rd party system)

1 September 2021

Geographical area covered (offline during plugin upgrade)

North Latitude	East Longitude	South Latitude	West Longitude
-3.50522	39.9177	-3.51619	39.9019

Language(s) of written materials

English

People & Groups

Data Creators	Muthui, MK, Takashima, E, Omondi, BR, Kinya, C, Muasya, WI, Nagaoka, H, Mwai, K, Orindi, B, Wambua, J, Bousema, T, Drakeley, C, Blagborough, AM, Marsh, K, Bejon, P and Kapulu, MC
LSHTM Faculty/Department	Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom, Ehime University, Matsuyama, Japan, KEMRI Wellcome Trust Research Programme, Radboud University Medical Centre, Nijmegen, The Netherlands, Cambridge University, Cambridge, United Kingdom, University of Oxford, Oxford, United Kingdom