Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes
; Takashima, E; Omondi, BR; Kinya, C; Muasya, WI; Nagaoka, H; Mwai, K; Orindi, B; Wambua, J; Bousema, T; Drakeley, C; Blagborough, AM; Marsh, K; Bejon, P and Kapulu, MC
(2021).
Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes.
[Dataset].
Harvard Dataverse.
https://doi.org/10.7910/DVN/WL8TRW
We used data from a longitudinally monitored cohort of children and adults from Kilifi county located along the Kenyan coast collected between 1998-2016 to describe the factors associated with the acquisition of antibody responses to antigens expressed on the surface of mature gametocytes. A panel of candidate gametocyte antigens were identified and produced as recombinant protein for this analysis. The datasets comprise data from cross-sectional surveys carried out to assess parasite prevalence. The datasets were used to carry out analyses aimed at describing the seroprevalence of antibodies to the candidate antigens, and assess the factors associated with antibody responses to these antigens. The overall aim of the analyses was to improve our understanding of immunity to the transmissible stages of the malaria parasite.
Keywords
Medicine; Health and Life Sciences| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Questionnaire |
| Date | 1 September 2021 |
| Geographical area covered (offline during plugin upgrade) |
North East South West -3.50522 39.9177 -3.51619 39.9019 |
| Language(s) of written materials | English |
| Creator(s) |
Muthui, MK; Takashima, E; Omondi, BR; Kinya, C; Muasya, WI; Nagaoka, H; Mwai, K; Orindi, B; Wambua, J; Bousema, T; Drakeley, C; Blagborough, AM; Marsh, K; Bejon, P and Kapulu, MC
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection (-2019) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom; Ehime University, Matsuyama, Japan; KEMRI Wellcome Trust Research Programme; Radboud University Medical Centre, Nijmegen, The Netherlands; Cambridge University, Cambridge, United Kingdom; University of Oxford, Oxford, United Kingdom |
| Date Deposited | 07 Sep 2021 16:13 |
| Last Modified | 23 Oct 2025 13:53 |
| Publisher | Harvard Dataverse |
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