Replication Data for: Nasopharyngeal pneumococcal concentration among children in a longitudinal study of household respiratory virus transmission in Kilifi, Kenya

Morpeth, SC; Munywoki, PK; Hammitt, LL; Bett, A; Bottomley, CORCID logo; Onyango, CO; Murdoch, DR; Nokes, DJ and Scott, AORCID logo (2018). Replication Data for: Nasopharyngeal pneumococcal concentration among children in a longitudinal study of household respiratory virus transmission in Kilifi, Kenya. [Dataset]. Harvard Dataverse. https://doi.org/10.7910/DVN/A0AXNN
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These data include pneumococcal concentration measured by quantitative PCR from nasopharyngeal swab samples collected from children during a longitudinal study of viral transmission among households in rural Kenya. The parent study has been described elsewhere, but in brief, swabs were collected twice weekly from all members of 47 households in Kilifi County, Kenya during the RSV season from December 2009 until June 2010. Swabs collected during periods of upper respiratory tract infection associated with viral (RSV or rhinovirus) infection from children <5 years old, swabs from the 2 weeks prior to such viral infection periods and swabs from the 4 weeks following such periods, were examined. A quantitative pneumococcal PCR (lytA) was adjusted for the concentration of human DNA present (as measured by a quantitative alu PCR) for each such swab.

Additional Information

Access to the dataset is restricted as it contains sensitive information on participants. Accompanying documentation is available under open access. For more detailed information beyond the metadata and documentation provided, there is a process of managed access requiring submission of a request form for consideration by our Data Governance Committee ( http://kemri-wellcome.org/about-us/#ChildVerticalTab_15 ). Please contact the Data Governance Committee via this email address- dgc@kemri-wellcome.org

Keywords

Streptococcus pneumoniae; Carriage; Colonisation; RSV; Rhinovirus; Viral; Nasopharyngeal; Concentration,; Density; Quantitative PCR

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