International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact
Gladstone, RA, Lo, SW, Lees, JA, Croucher, NJ, van Tonder, AJ, Corander, J, Page, AJ, Marttinen, P, Bentley, LJ, Ochoa, TJ, Leung Ho, P, du Plessis, M, Cornick, JE, Kwambana-Adams, B, Benisty, R, Nzenze, SA, Madhi, SA, Hawkins, PA, Everett, DB, Antonio, M, Dagan, R, Klugman, KP, von Gottberg, A, McGee, L, Breiman, RF and Bentley, SD.
2019.
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
[Online].
EBio Medicine.
Available from:
https://doi.org/10.1016/j.ebiom.2019.04.021
Gladstone, RA, Lo, SW, Lees, JA, Croucher, NJ, van Tonder, AJ, Corander, J, Page, AJ, Marttinen, P, Bentley, LJ, Ochoa, TJ, Leung Ho, P, du Plessis, M, Cornick, JE, Kwambana-Adams, B, Benisty, R, Nzenze, SA, Madhi, SA, Hawkins, PA, Everett, DB, Antonio, M, Dagan, R, Klugman, KP, von Gottberg, A, McGee, L, Breiman, RF and Bentley, SD.
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact
[Internet].
EBio Medicine;
2019.
Available from:
https://doi.org/10.1016/j.ebiom.2019.04.021
Gladstone, RA, Lo, SW, Lees, JA, Croucher, NJ, van Tonder, AJ, Corander, J, Page, AJ, Marttinen, P, Bentley, LJ, Ochoa, TJ, Leung Ho, P, du Plessis, M, Cornick, JE, Kwambana-Adams, B, Benisty, R, Nzenze, SA, Madhi, SA, Hawkins, PA, Everett, DB, Antonio, M, Dagan, R, Klugman, KP, von Gottberg, A, McGee, L, Breiman, RF and Bentley, SD
(2019).
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
[Data Collection].
EBio Medicine.
https://doi.org/10.1016/j.ebiom.2019.04.021
Description
Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of genetic background.