Targeted Amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity in Kilifi, KENYA
Wamae, K
; Ndwiga, L; Kharabora, O; Kimenyi, KM; Osoti, V; de Laurent, ZR; Wambua, J; Musyoki, J; Ngetsa, C; Kalume, P; Mwambingu, G; Hamaluba, M; van der Pluijm, RW; Dondorp, AM; Bailey, JA; Juliano, JJ; Bejon, P and Ochola-Oyier, LI
(2022).
Targeted Amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity in Kilifi, KENYA.
[Dataset].
Zenodo.
https://doi.org/10.5281/zenodo.6243928
; Ndwiga, L; Kharabora, O; Kimenyi, KM; Osoti, V; de Laurent, ZR; Wambua, J; Musyoki, J; Ngetsa, C; Kalume, P; Mwambingu, G; Hamaluba, M; van der Pluijm, RW; Dondorp, AM; Bailey, JA; Juliano, JJ; Bejon, P and Ochola-Oyier, LI
(2022).
Targeted Amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity in Kilifi, KENYA.
[Dataset].
Zenodo.
https://doi.org/10.5281/zenodo.6243928
These data were generated from targeted amplicon sequencing of Plasmodium falciparum ama1 and mdr1 genes in samples collected from Kilifi, at the coast of Kenya.
Two objectives were explored:
[1] To determine temporal changes in the genetic diversity of malaria parasites in asymptomatic and febrile infections.
[2] To track within-host parasite diversity, throughout treatment in a clinical drug trial.
Keywords
next generation sequencing; targeted amplicon sequencing; deep sequencing; malaria; asymptomatic infections; antimalarial drug trial| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Unknown |
| Date | 23 February 2022 |
| Language(s) of written materials | English |
| Creator(s) |
Wamae, K; Ndwiga, L; Kharabora, O; Kimenyi, KM; Osoti, V; de Laurent, ZR; Wambua, J; Musyoki, J; Ngetsa, C; Kalume, P; Mwambingu, G; Hamaluba, M; van der Pluijm, RW; Dondorp, AM; Bailey, JA; Juliano, JJ; Bejon, P and Ochola-Oyier, LI
|
| Associated roles | Ochola-Oyier, LI (Supervisor); Bejon, P (Supervisor) and Sutherland, CJ (Supervisor) |
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection (-2019) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Date Deposited | 28 Feb 2022 11:55 |
| Last Modified | 14 Oct 2025 10:04 |
| Publisher | Zenodo |
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