Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth
Fletcher, HA
; Keyser, A; Bowmaker, M; Sayles, P; Kaplan, G; Hussey, G; Hill, A and Hanekom, W
(2009).
Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth.
[Dataset].
NCBI Gene Expression Omnibus.
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE14408
; Keyser, A; Bowmaker, M; Sayles, P; Kaplan, G; Hussey, G; Hill, A and Hanekom, W
(2009).
Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth.
[Dataset].
NCBI Gene Expression Omnibus.
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE14408
Transcpripts upregulated by both BCG and PPD were identified in 5 infants and pathway analysis and gene ontology were performed using differentially expressed genes. In this study the frozen PBMC of 5 infants were thawed and stimulated for 12 hours with either BCG or PPD or rested in media alone for 12 hours. The transcripts from the unstimulated PBMC were compared to the PPD and BCG induced transcripts.
Keywords
Response to antigen stimulation| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Experiment: Field Intervention |
| Date | 24 February 2009 |
| Language(s) of written materials | English |
| Creator(s) |
Fletcher, HA; Keyser, A; Bowmaker, M; Sayles, P; Kaplan, G; Hussey, G; Hill, A and Hanekom, W
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection (-2019) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Date Deposited | 11 Jan 2019 10:01 |
| Last Modified | 08 Jul 2021 12:49 |
| Publisher | NCBI Gene Expression Omnibus |
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