Vasileva, H, Butcher, RMR and Roberts, C. 2018. Conjunctival transcriptome profiling of Solomon Islanders with active trachoma but without ocular Chlamydia trachomatis infection. [Online]. NCBI Gene Expression Omnibus. Available from: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106961
Vasileva, H, Butcher, RMR and Roberts, C. Conjunctival transcriptome profiling of Solomon Islanders with active trachoma but without ocular Chlamydia trachomatis infection [Internet]. NCBI Gene Expression Omnibus; 2018. Available from: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106961
Vasileva, H, Butcher, RMR and Roberts, C (2018). Conjunctival transcriptome profiling of Solomon Islanders with active trachoma but without ocular Chlamydia trachomatis infection. [Data Collection]. NCBI Gene Expression Omnibus. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE106961
Description
The prevalence of trachomatous inflammation–follicular (TF) in Solomon Island children aged 1–9 years is high enough to warrant, among other interventions, mass distribution of azithromycin. However, over 90% of those with TF did not have concurrent Chlamydia trachomatis infection.
We analysed the transcriptome of children with TF and Ct infection, children diagnosed with TF but no Ct infection and children with neither TF nor Ct infection to better understand host responses during an episode of TF, and investigate whether it can provide any clues about the aetiology of TF in this context.
Keywords
| Data capture method | Experiment |
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| Date (Date published in a 3rd party system) | 1 March 2018 |
| Language(s) of written materials | English |
| Data Creators | Vasileva, H, Butcher, RMR and Roberts, C |
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| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
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| Date Deposited | 22 Mar 2018 14:21 |
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| Last Modified | 09 Jul 2021 11:22 |
| Publisher | NCBI Gene Expression Omnibus |
