5150 49 18937 4 111378 document 18937 CRP_dataset_open.csv text/csv a7239e94f0b87132dee938a158b4121ec2892a71f746cec8e8e0b9d73e28dba7 SHA256 1088476 2026-04-15 10:40:10 https://datacompass.lshtm.ac.uk/id/eprint/5150/2/CRP_dataset_open.csv 5150 2 1 text/csv Dataset en public cc_by_4

CRP_dataset_open.csv

data indefinite Dataset underpinning research on the performance of CRP as a screening tool for TB analysis 18938 4 111384 document 18938 CRP_dataset_controlled.zip application/zip f25c1ab17d395c94a9ee3b226d659894770f1762c9221a1ede82f47cf9499c25 SHA256 241 2026-04-15 10:42:46 https://datacompass.lshtm.ac.uk/id/eprint/5150/3/CRP_dataset_controlled.zip 5150 3 2 application/zip Dataset en staffonly datasharingagreement

CRP_dataset_controlled.zip

data indefinite Controlled access dataset - consult codebook for details 18939 2 111401 document 18939 CRP_dataset_codebook.html text/html 4d4851406677137da759b7d56bc9b29d11934508873e17a64ec572c49ea8276e SHA256 27409 2026-04-15 11:44:38 https://datacompass.lshtm.ac.uk/id/eprint/5150/4/CRP_dataset_codebook.html 5150 4 4 text/html Text en public cc_by_4

CRP_dataset_codebook.html

documentation indefinite Codebook for data collected to assess performance of CRP as a screening tool for TB analysis archive 421 disk0/00/00/51/50 2026-04-15 11:07:21 2026-04-15 11:44:49 2026-04-15 11:07:21 data_collection show Ruperez Larrea Maria 0000-0001-8322-7881 TRUE 996cb20c16e3d9c2b4d00323e407a30a PrincipalInvestigator Ayles Helen TRUE b24353655384120d5cae05b93c8f7f58 CoInvestigator Floyd Sian 0000-0002-8615-7601 TRUE cadcaff32828ae5ed3c2311ae02e690b CoInvestigator Hayes Richard 0000-0002-1729-9892 TRUE 8de72a395621a783176e16a6bd70c710 CoInvestigator Schaap Ab 0000-0002-5959-526X TRUE a80b19225f306d0ed5552865b0d638b7 CoInvestigator Klinkenberg Eveline FALSE CoInvestigator Gachie Thomas TRUE 62f2a5895bfd4a8127a96abb8c2e949f CoInvestigator Kosloff Barry TRUE 80728146aa764cf365401e2611a745d7 CoInvestigator Shanaube Kwame FALSE e7a9df617c02c6b5c387181a7bf9010c Researcher de Haas Petra FALSE Researcher Fidler Sarah FALSE Researcher Mureithi Linda FALSE Researcher Wapamesa Chali FALSE Researcher Burnett James M FALSE London School of Hygiene & Tropical Medicine, London, United Kingdom Zambart, University of Zambia, Lusaka, Zambia Health Systems Trust KNCV Tuberculosis Foundation, The Hague, Netherlands Imperial College, London, United Kingdom London School of Economics, London, United Kingdom University of Sheffield, Sheffield, United Kingdom Delft Imaging QIAGEN The Union EPID ITCR Tuberculosis C-reactive Protein. Screening Community Data is made available in two forms: (1) an open access data that has been processed to broaden participant demographics, and a (2) controlled access dataset that contains additional information. Consult codebook for information. Dataset containing results of an investigation to determine the prevalence of tuberculosis (TB) among enrolled participants of the TREATS study between February 19 and August 11, 2019. Participants were aged 15 years and over and located in one of 3 communities in Zambia or 1 community in South Africa. TB was detected using point-of-care C-reactive protein testing, alone and combined with symptom screening, that covered self-reported symptoms for cough, fever, chest pain, night sweats, and weight loss. This is the minimal dataset required to conduct the analysis presented in the published paper: Ruperez M, Shanaube K, Mureithi L, Wapamesa C, Burnett MJ, Kosloff B, de Haas P, Hayes R, Fidler S, Gachie T, Schaap A, Floyd S, Klinkenberg E, Ayles H; TREATS study team. Use of point-of-care C-reactive protein testing for screening of tuberculosis in the community in high-burden settings: a prospective, cross-sectional study in Zambia and South Africa. Lancet Glob Health. 2023 May;11(5):e704-e714. doi: 10.1016/S2214-109X(23)00113-4. Erratum in: Lancet Glob Health. 2023 Jul;11(7):e1011. doi: 10.1016/S2214-109X(23)00222-X. PMID: 37061309. The study protocol and ICF were approved by LSHTM Ethics Committee (ref: 14905) as well as the University of Zambia Biomedical Research Ethics Committee (ref: 005–02–18) and Pharma-Ethics Ltd in South Africa (ref: 180219727). 2026-04-15 completed London School of Hygiene & Tropical Medicine 10.17037/DATA.00005150 Dataset London School of Hygiene & Tropical Medicine, London, United Kingdom Zambart, University of Zambia, Lusaka, Zambia Health Sytems Trust EDCTP XTBC TREATS project SelfAdministeredQuestionnaire Observation.Laboratory.Participant MeasurementsAndTests.Physical restricted London, United Kingdom European and Developing Countries Clinical Trials Partnership TREATS Dataset Quantitative Data was captured at the TREATS TB prevalence survey in the community at time of participant's enrolment and next day visit through electronic data capturing (EDC) tools designed for that purpose. Socio-demographic and clinical characteristics were collected through a standardized questionnaire. Point-of-care CRP and HIV test results were also captured at the time of enrolment in the EDC tool, as well as the CAD score from the Chest-X ray. Results from Xpert tests and culture were captured by the laboratory information and management system in place in each of the sites and merged to rest of the data through study-id number. Informed consent and questionnaires were also translated in to local languages such as Nyanja and Bemba in Zambia and Xhosa in South Africa. RIA2016S-1632 en 2019-02-19 2019-08-11 https://researchonline.lshtm.ac.uk/id/eprint/4666926 https://researchonline.lshtm.ac.uk/id/eprint/4677290 https://researchonline.lshtm.ac.uk/id/eprint/4680487 TREATS European and Developing Countries Clinical Trials Partnership RIA2016S-1632 https://doi.org/10.13039/501100001713