Data were collected prospectively as part of a double-blind randomised controlled trial. Clinical assessments and symptom data were recorded at scheduled follow-up visits. Blood samples were assessed using microscopy and quantitative PCR, and for molecular genotyping of Plasmodium falciparum. All data were recorded on standardised case report forms and entered into electronic databases (REDCap, ODK, Excel). Individual-level clinical, parasitological, and laboratory data were cleaned, harmonised, and merged across study visits and data sources using unique participant identifiers. Data preparation included consistency checks, validation of dates and follow-up windows, and linkage of molecular genotyping results to clinical records. R software version 4.3 was used for data processing and cleaning. No identifiable information was included in the final dataset.