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documentation indefinite Codebook for CoHost study data archive 559 disk0/00/00/50/44 2026-03-02 15:32:07 2026-03-03 13:37:49 2026-03-02 15:32:07 data_collection show Zirimenya Ludoviko TRUE dfdf64063b138a70603f7d21a2b992fb Nkurunungi Gyaviira 0000-0003-4062-9105 TRUE a48ee0eddf888813b8e342fdb4b32087 Natukunda Agnes 0000-0003-1156-201X TRUE e8f9d6363d29c2ef6e98e7ac6b81948a Nassuna Jacent TRUE 47ada070bc38419b4613df6f2808262b Nakyesige Racheal TRUE b14308647d1e8c2256230fa86ae4d47e Nayebare Doreen TRUE 1402f6914913e11d16243a4716557775 Baine Claire FALSE e73516835b447351401058dd6b3ea990 Elliott Alison M. 0000-0003-2818-9549 TRUE d9d54503b6d617709b2d9f1aaf480651 Webb Emily 0000-0002-4019-7456 TRUE 37be87b3e3571ab56ac10ff692e63cd3 London School of Hygiene & Tropical Medicine, London, United Kingdom MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda Uganda Virus Research Institute, Entebbe, Uganda ITCR MRCUVRI Malaria SARS-CoV-2 Longitudinal data Research data made available upon request, subject to agreement to a 'light touch' licence to store data securely at all times. This data was collected from a longitudinal study nested within the Entebbe Mother and Baby Study birth cohort in Uganda. Adolescents were enrolled and followed up 6 and 12 months later. Blood samples were collected at each visit for SARS-CoV-2 serology. Malaria exposure was defined using prospectively collected data on clinical malaria (from birth to 10 years), asymptomatic parasitaemia at annual visits, and antibody responses to Plasmodium falciparum merozoite surface protein 2 (PfMSP-2) and apical membrane antigen 1 (PfAMA-1). The primary outcome was SARS-CoV-2 seropositivity, based on spike and nucleocapsid IgG responses, with seropositivity cut-offs derived from pre-pandemic samples. Secondary outcomes, including antibody concentrations and symptomatic PCR-confirmed disease, were explored. 2026-02-25 completed London School of Hygiene & Tropical Medicine 10.17037/DATA.00005044 Dataset MRC/UVRI & LSHTM Uganda Research Unit, Entebbe, Uganda London School of Hygiene & Tropical Medicine, London, United Kingdom XMAL Immunomodulation and Vaccines Group Observation.Field.Participant Observation.Laboratory.Participant restricted London, United Kingdom Science for Africa Foundation National Institute for Health Research (NIHR) Medical Research Council CoHost Project VAnguard POPVAC programme Dataset Quantitative GCA/SARSCov2-2-20-002 en 2011-04-30 2022-12-31 CoHost Project Science for Africa Foundation GCA/SARSCov2-2-20-002 https://doi.org/10.13039/100031746 VAnguard National Institute for Health Research (NIHR) NIHR134531 http://dx.doi.org/10.13039/501100000272 POPVAC programme Medical Research Council MR/R02118X/1 https://doi.org/10.13039/501100000265