Data supporting "Helminth-driven gut inflammation and microbial translocation are linked to altered vaccine responses in rural Uganda"

4505 28 16903 2 94702 document 16903 MTmarkers_data.csv text/plain 83973ae86ee8d7f47d9fb4b184e98fb184580d940da9d94544567395ccb6819e SHA256 48 2025-01-20 16:40:45 https://datacompass.lshtm.ac.uk/id/eprint/4505/1/MTmarkers_data.csv 4505 1 1 text/plain Dataset en staffonly datasharingagreement

MTmarkers_data.csv

data indefinite Data on helminth infections, vaccine responses and gut microbial translocation, from the POPVAC A trial 16904 2 94704 document 16904 MTmarkers_data_codebook.html text/html 3dd388e3b7bc650cf41314b14a465b57dcabd4bed243e8aef855dd4ce5211a79 SHA256 14333 2025-01-20 16:41:05 https://datacompass.lshtm.ac.uk/id/eprint/4505/2/MTmarkers_data_codebook.html 4505 2 2 text/html Text en public cc_by_4

MTmarkers_data_codebook.html

documentation indefinite Codebook for MT Markers dataset 17348 1 95674 document 17348 indexcodes.txt text/plain 413229d40dfe3606683cc463bdc725708ca85ddf84494184e1a004d2a6324230 SHA256 2186 2025-02-07 10:27:02 https://datacompass.lshtm.ac.uk/id/eprint/4505/3/indexcodes.txt 4505 3 3 text/plain en public

indexcodes.txt

http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/16904 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/16904 http://eprints.org/relation/isIndexCodesVersionOf https://datacompass.lshtm.ac.uk/id/document/16904 indefinite Generate index codes conversion from Text to indexcodes archive 241 disk0/00/00/45/05 2025-01-20 16:44:34 2025-04-03 09:28:27 2025-01-20 16:44:34 data_collection show Nkurunungi Gyaviira 0000-0003-4062-9105 TRUE a48ee0eddf888813b8e342fdb4b32087 Nassuuna Jacent TRUE Researcher Sterk Joas FALSE Researcher Webb Emily 0000-0002-4019-7456 TRUE 37be87b3e3571ab56ac10ff692e63cd3 Researcher Elliott Alison M. 0000-0003-2818-9549 TRUE d9d54503b6d617709b2d9f1aaf480651 Researcher Zirimenya Ludoviko TRUE dfdf64063b138a70603f7d21a2b992fb Researcher Natukunda Agnes 0000-0003-1156-201X TRUE e8f9d6363d29c2ef6e98e7ac6b81948a Researcher Nkangi Ronald TRUE Researcher Walusimbi Bridgious TRUE 90fc9313c83545a558f099441943bf78 Researcher Amongin Rebecca TRUE 7e2dfca4ba584437b21260b025ba7353 London School of Hygiene & Tropical Medicine, London, United Kingdom MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda Leiden University Medical Center, Leiden, Netherlands Data supporting "Helminth-driven gut inflammation and microbial translocation are linked to altered vaccine responses in rural Uganda" ITIB ITCR UGUCI Vaccine responses Schistosoma mansoni Gut inflammation Gut microbial translocation Helminth infections To access the data, requests must be made to the POPVAC A trial PI (Professor Alison Elliott). The request will be reviewed by the PI together with the POPVAC A investigator team. The request will be reviewed based on scientific value and to ensure there is no overlap with existing work. If the request is approved, before data is shared, ethics approval will need to be obtained in your host institution and a Data Transfer Agreement with the MRC/UVRI and LSHTM Uganda Research Unit must be completed. This dataset comprises individual-level data from participants in the POPVAC A randomised controlled trial. POPVAC A was conducted among schoolchildren from Koome islands, Uganda (a schistosomiasis-endemic setting). Variables include data on socio-demographic characteristics, helminth infections, vaccine-specific responses, and stool and plasma markers of gut inflammation and microbial translocation. 2025-01-20 completed London School of Hygiene & Tropical Medicine 10.17037/DATA.00004505 Dataset MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda London School of Hygiene & Tropical Medicine, London, United Kingdom Immunomodulation and Vaccines group SelfAdministeredQuestionnaire.FixedForm Observation.Laboratory MeasurementsAndTests restricted London, United Kingdom Medical Research Council Wellcome Trust POPVAC The impact of differential parasite exposure on immunological and metabolic predictors of vaccine response in the tropics Dataset Quantitative MR/R02118X/1 and MC_PC_21034 en 2019-07-01 2024-06-30 Helminth driven gut inflammation and microbial translocation associate with altered vaccine responses in rural Uganda. https://researchonline.lshtm.ac.uk/id/eprint/4675736 POPVAC Medical Research Council MR/R02118X/1 and MC_PC_21034 http://dx.doi.org/10.13039/501100000265 The impact of differential parasite exposure on immunological and metabolic predictors of vaccine response in the tropics Wellcome Trust 224263/Z/21/Z http://dx.doi.org/10.13039/100010269 2025-01-20