VITALITY: Vitamin D for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology

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VITALITY_baseline_data.txt

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3868_UserGuide.html

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indexcodes.txt

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VITALITY_baseline_data_codebook.html

documentation indefinite Codebook for VITALITY trial baseline dataset 17162 1 95488 document 17162 indexcodes.txt text/plain a9273850b8af19252da3008568fd6d9361b7531257d18255dea717690d5073c4 SHA256 1853 2025-02-07 10:23:29 https://datacompass.lshtm.ac.uk/id/eprint/3868/6/indexcodes.txt 3868 6 6 text/plain en public

indexcodes.txt

http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/16413 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/16413 http://eprints.org/relation/isIndexCodesVersionOf https://datacompass.lshtm.ac.uk/id/document/16413 indefinite Generate index codes conversion from Text to indexcodes 17163 1 95489 document 17163 indexcodes.txt text/plain fd499d2fb69bb2e36c7a45545a32519ec5359311d3fa7bb99bf5941a123c9306 SHA256 10429 2025-02-07 10:23:29 https://datacompass.lshtm.ac.uk/id/eprint/3868/7/indexcodes.txt 3868 7 7 text/plain en public

indexcodes.txt

http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/16415 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/16415 http://eprints.org/relation/isIndexCodesVersionOf https://datacompass.lshtm.ac.uk/id/document/16415 indefinite Generate index codes conversion from Text to indexcodes archive 29 disk0/00/00/38/68 2024-08-20 16:08:29 2026-01-29 10:41:16 2024-08-20 16:08:29 data_collection show Simms Vicky 0000-0002-4897-458X TRUE 7187062ef751bd3fcc09dd9a13d6211c Ferrand Rashida 0000-0002-7660-9176 TRUE e972b46de858cfdb22ba9444cafbd0b4 DataManager Bandason Tsitsi 0000-0003-0066-8345 TRUE fb4132a4a6f62e97e660fae80f9a2e47 Researcher Filteau Suzanne 0000-0002-1119-6825 TRUE 203ecc92f71b732f9b692e8b55b74b91 London School of Hygiene & Tropical Medicine, London, United Kingdom Biomedical Research and Training Institute, Zimbabwe University Teaching Hospital Lusaka, Lusaka, Zambia VITALITY: Vitamin D for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology - Baseline Data EPIH ITCR HIV Bone and mineral metabolism Adolescence Puberty Zimbabwe Applications require approval by representatives from the country where data was collected. To apply for access, complete the application form, outlining the data variables in which you are interested. If approved, applicants will need to sign a data transfer agreement outlining permitted use and security conditions. Consult codebook for further information. The VITamin D for AdoLescents with HIV to reduce musculoskeletal morbidity and ImmunopaThologY (VITALITY) trial is a phase III two-site, individually randomised, double-blinded, placebo-controlled trial. Participants were randomised 1:1 to receive weekly vitamin D and daily 500mg calcium carbonate supplementation or placebo for 48 weeks. Participants were followed for a further 48 weeks to investigate the sustainability of intervention effect. 842 children aged 11-19 years with perinatally-acquired HIV resident in greater Harare (Zimbabwe site) or within Lusaka (Zambia site) were recruited. The baseline dataset contains information on the participants' living environment, health status, received treatments, exercise levels, and other information. 2024-06-11 completed London School of Hygiene & Tropical Medicine 10.17037/DATA.00003868 Dataset London School of Hygiene & Tropical Medicine, London, United Kingdom The Health Research Unit Zimbabwe (THRUZIM) Interview.FaceToFace Observation.Laboratory MeasurementsAndTests.Physical 171 KM BEV restricted London, United Kingdom European and Developing Countries Clinical Trials Partnership VITamin D for AdoLescents with HIV to reduce musculoskeletal morbidity and ImmunopaThologY (VITALITY): an individually randomised, double-blinded placebo-controlled triaL Dataset Quantitative Participants completed a researcher-administered questionnaire on demographic and social characteristics and medical history, and a dietary assessment. They gave a blood sample for CD4 and HIV viral load tests (full blood count in Zambia). They had anthropometric measurements (height, sitting height and weight in both countries; waits, hip, calf, triceps circumfererence, skinfold thickness, Tanita bioimedance assessment Bodpod in Zambia). They had a total body and lumbar spine DXA scan. Those in Zimbabwe had a pQCT scan and a hand X-ray using the iDXA. A blood sample was taken for measurements of vitamin D pathway metabolites, bone turnover markers and iPTH, and for additional immunology studies in Zambia. 123 participants in each country had a rectal swab. RIA2018CO-2512 en sn 2021-02-04 2021-11-23 VITALITY trial website https://www.vitality-trial.co.uk/ project Patterns of linear growth among children and adolescents living with HIV on antiretroviral therapy in Zimbabwe and Zambia https://doi.org/10.1186/s12879-025-10669-0 paper Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial. https://researchonline.lshtm.ac.uk/id/eprint/4664773 Patterns of linear growth among children and adolescents living with HIV on antiretroviral therapy in Zimbabwe and Zambia https://researchonline.lshtm.ac.uk/id/eprint/4675231 Methods for measuring body composition in Zambian adolescents living with HIV. https://researchonline.lshtm.ac.uk/id/eprint/4678862 VITamin D for AdoLescents with HIV to reduce musculoskeletal morbidity and ImmunopaThologY (VITALITY): an individually randomised, double-blinded placebo-controlled triaL European and Developing Countries Clinical Trials Partnership RIA2018CO-2512 http://dx.doi.org/10.13039/501100001713 2024-06-11