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      <item>London School of Hygiene &amp; Tropical Medicine, London, United Kingdom</item>
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    <title>Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies</title>
    <divisions>
      <item>ITCR</item>
    </divisions>
    <keywords>
      <item>trachoma</item>
      <item>serology</item>
      <item>serosurveillance</item>
      <item>seroepidimiology</item>
    </keywords>
    <abstract>Data sets from 2700 Uganda, 952 Laotian and 1868 Gambian participants who have informed consent to participate in a cluster-randomised serological study to determine the seroprevalence of antibodies against Chlamydia trachomatis. Specimens were analysed from May 2014-May 2016.
Each data set contains normalised OD values for an anti-Pgp3 specific ELISA, which were used to generate a series of thresholds to define seropositive and seronegative samples.</abstract>
    <date>2016-08</date>
    <date_type>completed</date_type>
    <publisher>London School of Hygiene &amp; Tropical Medicine</publisher>
    <id_number>10.17037/DATA.111</id_number>
    <data_type>Dataset</data_type>
    <copyright_holders>
      <item>London School of Hygiene &amp; Tropical Medicine, London, United Kingdom</item>
    </copyright_holders>
    <collection_mode>
      <item>Experiment.Laboratory</item>
    </collection_mode>
    <full_text_status>public</full_text_status>
    <place_of_pub>London, United Kingdom</place_of_pub>
    <funders>
      <item>Wellcome Trust</item>
    </funders>
    <resourcetype>
      <resourcetypegeneral>Dataset</resourcetypegeneral>
      <resourcetype>Quantitative</resourcetype>
    </resourcetype>
    <collection_method>Dried blood spots were collected onto filter paper from a finger-prick blood sample from consenting participants in Laos, Uganda and The Gambia. Samples were allowed to air-dry, then were stored at -20C before being shipped to LSHTM for testing.
Samples were eluted overnight and assayed using an-Pgp3 specific ELISA.
Data presented are normalised OD values (read at optical density 450)</collection_method>
    <grant>098521/B/12/Z</grant>
    <bounding_box>
      <item>
        <north_edge>13.8073</north_edge>
        <east_edge>-13.7315</east_edge>
        <south_edge>13.1636</south_edge>
        <west_edge>-15.2779</west_edge>
      </item>
      <item>
        <north_edge>3.43366</north_edge>
        <east_edge>34.368</east_edge>
        <south_edge>1.86434</south_edge>
        <west_edge>32.775</west_edge>
      </item>
      <item>
        <north_edge>22.6232</north_edge>
        <east_edge>107.743</east_edge>
        <south_edge>14.1675</south_edge>
        <west_edge>101.415</west_edge>
      </item>
    </bounding_box>
    <language>
      <item>en</item>
    </language>
    <collection_date>
      <date_from>2014-02</date_from>
      <date_to>2014-11</date_to>
    </collection_date>
    <repo_link>
      <item>
        <title>Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies.</title>
        <link>https://researchonline.lshtm.ac.uk/id/eprint/3405247</link>
      </item>
    </repo_link>
    <funders_info>
      <item>
        <funder_name>Wellcome Trust</funder_name>
        <grant>098521/B/12/Z</grant>
        <funder_id>http://dx.doi.org/10.13039/100010269</funder_id>
      </item>
    </funders_info>
    <ukri_date_sub>2016-08</ukri_date_sub>
  </eprint>
</eprints>
