Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa: Lesedi Kamoso study data

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http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/16456 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/16456 http://eprints.org/relation/isIndexCodesVersionOf https://datacompass.lshtm.ac.uk/id/document/16456 indefinite Generate index codes conversion from Text to indexcodes archive 59 disk0/00/00/02/43 2016-10-21 13:53:40 2024-09-11 15:33:58 2016-10-21 13:53:40 data_collection show Karat Aaron S. 0000-0001-9643-664X TRUE 089a4d053d67a6b24ca5ec236bbc5777 Omar Tanvier FALSE von Gottberg Anne FALSE Tlali Mpho FALSE Chihota Violet N. FALSE Churchyard Gavin J. TRUE 285da50b2e6269d09abfbeb49da9092d Fielding Katherine L. 0000-0002-6524-3754 TRUE 0aa3885fd6201076535210a253a38f98 Johnson Suzanne FALSE Martinson Neil A. FALSE McCarthy Kerrigan FALSE Wolter Nicole FALSE 288d7641c18f28679b149e6c9c7e4e1f Wong Emily B. FALSE Charalambous Salome FALSE Grant Alison D. 0000-0002-2437-5195 TRUE b0df4f9b5b9ba10639ecece0cb30bd4f London School of Hygiene & Tropical Medicine, London, United Kingdom The Aurum Institute, Johannesburg, South Africa Foundation for Professional Development, Pretoria, South Africa The University of the Witwatersrand, Johannesburg, South Africa National Health Laboratory Services, South Africa Perinatal HIV Research Unit, Soweto, Johannesburg, South Africa Johns Hopkins Center for TB Research Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa: Lesedi Kamoso study data EPID ITCR Tuberculosis HIV Autopsy Mortality Disease prevalence Minimally invasive autopsy Cause of death Opportunistic infections Infectious Diseases HIV diagnosis and management Tuberculosis diagnosis and management tuberculosis treatment Cryptococcal meningitis Pneumonia Bacterial and viral diseases Documentation converted from text to HTML on 11 Sep 2024. Early mortality among HIV-positive adults starting antiretroviral therapy (ART) remains high in resource-limited settings, with tuberculosis (TB) the leading cause of death. However, current methods to estimate TB-related deaths are inadequate and most autopsy studies do not adequately represent those attending primary health clinics (PHCs). The TB Fast Track study aimed to determine the autopsy prevalence of TB and other infections in adults enrolled at South African PHCs in the context of a pragmatic trial of empiric TB treatment. This dataset contains basic demographic information and lab investigation results of 34 HIV-positive individuals who died after study enrolment. This includes MGIT culture and Xpert MTB/RIF; aerobic and fungal cultures; and histological findings 2016-05-06 completed London School of Hygiene & Tropical Medicine 10.17037/DATA.122 Dataset London School of Hygiene & Tropical Medicine, London, United Kingdom XTBC Other restricted London, United Kingdom Bill and Melinda Gates Foundation Dataset Quantitative Adults with CD4 150 cells/L, not on ART or TB treatment, were enrolled to TB Fast Track and followed up for at least six months. Minimally-invasive autopsy (MIA) was conducted as soon as possible after death. Lungs, liver, and spleen were biopsied; blood, CSF, and urine aspirated; and bronchoalveolar lavage fluid obtained. Samples underwent mycobacterial, bacterial, and fungal culture; molecular testing (including Xpert MTB/RIF); and histological examination. OPP1083118 -23.7159 30.7727 -26.3042 27.2791 en 2013-10-10 2015-06-03 Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa. https://researchonline.lshtm.ac.uk/id/eprint/3071548 Bill and Melinda Gates Foundation OPP1083118 http://dx.doi.org/10.13039/100000865 2016-05-06