206 26 1974 2 6704 document 1974 S1_Additional_Actives_Table.XLSX application/vnd.openxmlformats-officedocument.spreadsheetml.sheet fcb95d90f9bb6d70d05990527f5b089c3310eb0e512f8a6a557a8dafabdedf68 SHA256 105406 2016-05-04 10:42:58 https://datacompass.lshtm.ac.uk/id/eprint/206/1/S1_Additional_Actives_Table.XLSX 206 1 1 application/vnd.openxmlformats-officedocument.spreadsheetml.sheet Dataset en public cc_by

S1_Additional_Actives_Table.XLSX

data indefinite Table of additional actives obtained during the screening. These structures were deprioritised relative to those in the body of the paper for the reasons given in the comment column. The assays are those described in the paper. ND = No data obtained. 1975 2 6706 document 1975 S2_StructuresTable.XLSX application/vnd.openxmlformats-officedocument.spreadsheetml.sheet 55e55779e90e36b5f40360f6ddb514a6ef9f1b66830abfa00460eea65a6357bb SHA256 248269 2016-05-04 10:43:00 https://datacompass.lshtm.ac.uk/id/eprint/206/2/S2_StructuresTable.XLSX 206 2 2 application/vnd.openxmlformats-officedocument.spreadsheetml.sheet Dataset en public cc_by

S2_StructuresTable.XLSX

data indefinite A list of structures described in the paper and a summary of findings obtained using the KNIME workflow ‘Know Your Molecule’ to access and present ChemBl data. The structures shown are those similar to the compound number listed in column 1 of the table archive 3 disk0/00/00/02/06 2016-05-04 10:47:15 2024-10-07 10:37:01 2016-05-04 10:47:15 data_collection show 1 Mansour Nuha R. TRUE d6d5ef73a1f8d42b2abd3afe35a7f8a0 Paveley Ross TRUE 7ab688be75fc5062997dcad7819f407a Gardner J. Mark F. FALSE Bell Andrew S. FALSE Parkinson Tanya FALSE Bickle Quentin TRUE ee3033271209bcd32f09c411773a926b Study consortium ITIM Library screening High throughput screening Cytotoxicity Optimization Schistosoma mansoni Schistosomiasis Drug discovery Data made to support the manuscript, "High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni". The table contains additional actives obtained during the screening. These structures were deprioritised relative to those in the body of the paper for the reasons given in the comment column. The assays are those described in the paper. ND = No data obtained. 2016-04-29 published PLOS Neglected Tropical Diseases Dataset London School of Hygiene & Tropical Medicine, London, United Kingdom Experiment public Medical Research Council Dataset Quantitative MR/K025430/1 en https://figshare.com/articles/High_Throughput_Screening_Identifies_Novel_Lead_Compounds_with_Activity_against_Larval_Juvenile_and_Adult_i_Schistosoma_mansoni_i_/3209953 data https://doi.org/10.1371/journal.pntd.0004659.s001 dataresource https://web.archive.org/web/20150912211631/http://www.wipo.int/research/en/details.jsp?id=464 data http://researchonline.lshtm.ac.uk/id/eprint/2548526 Medical Research Council MR/K025430/1 http://dx.doi.org/10.13039/501100000265 2016-04-29