Validation of the Recording of Acute Exacerbations of COPD in UK Primary Care Electronic Healthcare Records

196 42 1841 2 6357 document 1841 S1_TablesA-L.docx application/vnd.openxmlformats-officedocument.wordprocessingml.document 391df2344778c8865ff1aab13fe674575302fceef418c57a98a50f068bfe1013 SHA256 42775 2016-04-15 10:05:07 https://datacompass.lshtm.ac.uk/id/eprint/196/1/S1_TablesA-L.docx 196 1 1 application/vnd.openxmlformats-officedocument.wordprocessingml.document Dataset en public cc_by

S1_TablesA-L.docx

data indefinite Tables A-L: Comparison of responders and non-responders and PPV for various algorithms stratified by patient characteristics 1842 2 6359 document 1842 S2_AECOPD_Codes.docx application/vnd.openxmlformats-officedocument.wordprocessingml.document b6dcad731361d973af378ddc3524ebe9b20a28c78a0f68bb2d55caa83926d4e5 SHA256 44635 2016-04-15 10:05:10 https://datacompass.lshtm.ac.uk/id/eprint/196/2/S2_AECOPD_Codes.docx 196 2 2 application/vnd.openxmlformats-officedocument.wordprocessingml.document Text en public cc_by

S2_AECOPD_Codes.docx

documentation indefinite Codes to construct AECOPD algorithms 1850 2 6388 document 1850 Fig1.tif image/tiff a87d1069c69a53ef89a7904e0d53a84b58e84112389932ad13f9e71778a89083 SHA256 279330 2016-04-15 10:15:23 https://datacompass.lshtm.ac.uk/id/eprint/196/3/Fig1.tif 196 3 3 image/tiff Slideshow en public cc_by

Fig1.tif

documentation indefinite Patient flow through the study 1851 2 6390 document 1851 Table1.xls application/msword 591d4c7cdd9574a09417f3adb43c472c1d675adcea71691e7a0939e50df84253 SHA256 5632 2016-04-15 10:15:25 https://datacompass.lshtm.ac.uk/id/eprint/196/4/Table1.xls 196 4 4 application/msword Dataset en public cc_by

Table1.xls

data indefinite Description of the algorithms tested 1852 2 6392 document 1852 Table2.xls application/msword fa552a0cd4025161d4e8a928c01b149dace68188dce5ac7d0c7704545bb47ec0 SHA256 9728 2016-04-15 10:15:27 https://datacompass.lshtm.ac.uk/id/eprint/196/5/Table2.xls 196 5 5 application/msword Dataset en public cc_by

Table2.xls

data indefinite Characteristics of the 988 patients included in the analysis 1853 2 6394 document 1853 Table3.xls application/msword 7530e62ede6743a59865d85623c45d060600c39a26933882fa12f96dfa2ae037 SHA256 9728 2016-04-15 10:15:29 https://datacompass.lshtm.ac.uk/id/eprint/196/6/Table3.xls 196 6 6 application/msword Dataset en public cc_by

Table3.xls

data indefinite Flow of events through the study 1854 2 6396 document 1854 Table4.xls application/msword 9e71bd522acfa7d229963960962f338c168167fb35f886951c9d89fdbd6aa4e6 SHA256 9728 2016-04-15 10:15:31 https://datacompass.lshtm.ac.uk/id/eprint/196/7/Table4.xls 196 7 7 application/msword Dataset en public cc_by

Table4.xls

data indefinite PPV and sensitivity for the algorithms 1855 2 6398 document 1855 Table5.xls application/msword d33604a89edf2629f61ba0ffadca4ac166257596a5b2073139a06bcdbcf277f7 SHA256 9728 2016-04-15 10:15:33 https://datacompass.lshtm.ac.uk/id/eprint/196/8/Table5.xls 196 8 8 application/msword Dataset en public cc_by

Table5.xls

data indefinite PPV and sensitivity of the algorithms to identify AECOPD including only patients for whom additional information was available from their GP questionnaire 1856 2 6400 document 1856 Table6.xls application/msword 314b97bdbb56df01ea0906baf5d65561db997bcef095aeccdca44d3b3c0ec803 SHA256 5632 2016-04-15 10:15:35 https://datacompass.lshtm.ac.uk/id/eprint/196/9/Table6.xls 196 9 9 application/msword Dataset en public cc_by

Table6.xls

data indefinite PPV and sensitivity of composite strategies to identify AECOPD including only patients for whom additional information was available from their GP questionnaire 1857 1 6403 document 1857 indexcodes.txt text/plain 88f32df09ded496cb5563e25c05d337628ad2b900498237dd43f3effc1f3b23b SHA256 2199 2016-04-15 10:25:17 https://datacompass.lshtm.ac.uk/id/eprint/196/10/indexcodes.txt 196 10 10 text/plain other en public

indexcodes.txt

http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/1841 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/1841 http://eprints.org/relation/isIndexCodesVersionOf https://datacompass.lshtm.ac.uk/id/document/1841 indefinite Generate index codes conversion from Dataset to indexcodes 1858 1 6404 document 1858 indexcodes.txt text/plain 255c6b0cf4275dcdcded2049d9f442533fc347bdd1f9d7eac5e513fd3e676e10 SHA256 10183 2016-04-15 10:25:19 https://datacompass.lshtm.ac.uk/id/eprint/196/11/indexcodes.txt 196 11 11 text/plain other en public

indexcodes.txt

http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/1842 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/1842 http://eprints.org/relation/isIndexCodesVersionOf https://datacompass.lshtm.ac.uk/id/document/1842 indefinite Generate index codes conversion from Text to indexcodes 1859 2 6405 document 1859 lightbox.jpg image/png 13e15da59a9012d3051f55c833ed3fc916602ec2538f4dc71dbf16bdb3031d6f SHA256 37235 2016-04-15 10:25:59 https://datacompass.lshtm.ac.uk/id/eprint/196/12/lightbox.jpg 196 12 12 image/png other en public

lightbox.jpg

preview.jpg

medium.jpg

small.jpg

http://eprints.org/relation/isVersionOf https://datacompass.lshtm.ac.uk/id/document/1850 http://eprints.org/relation/isVolatileVersionOf https://datacompass.lshtm.ac.uk/id/document/1850 http://eprints.org/relation/issmallThumbnailVersionOf https://datacompass.lshtm.ac.uk/id/document/1850 indefinite Thumbnails conversion from Slideshow to thumbnail_small archive 3 disk0/00/00/01/96 2016-04-15 10:06:28 2021-08-24 09:25:45 2016-04-15 10:06:28 data_collection show Chotirmall Sanjay Haresh FALSE Rothnie Kieran TRUE bd6411d9f0ae4cff4620d4929d9761a2 Müllerová Hana FALSE Hurst John R. FALSE Smeeth Liam 0000-0002-9168-6022 TRUE b77507afb7742dd51f5b8bd6bc2dc017 Davis Kourtney FALSE Thomas Sara L TRUE 973ff40bc71f766955c077ef81f0071d Quint Jennifer 0000-0003-0149-4869 TRUE d381a7b204ea3f72cb5a9618fa938d75 London School of Hygiene & Tropical Medicine, London, United Kingdom Validation of the Recording of Acute Exacerbations of COPD in UK Primary Care Electronic Healthcare Records EPNC Antibiotics Chronic obstructive pulmonary disease Physicians Primary care Health services research Algorithms Diagnostic medicine Public and occupational health Acute Exacerbations of COPD (AECOPD) identified from electronic healthcare records (EHR) are important for research, public health and to inform healthcare utilisation and service provision. However, there is no standardised method of identifying AECOPD in UK EHR. We aimed to validate the recording of AECOPD in UK EHR. We randomly selected 1385 patients with COPD from the Clinical Practice Research Datalink. We selected dates of possible AECOPD based on 15 different algorithms between January 2004 and August 2013. Questionnaires were sent to GPs asking for confirmation of their patients’ AECOPD on the dates identified and for any additional relevant information. Responses were reviewed independently by two respiratory physicians. Positive predictive value (PPV) and sensitivity were calculated. 2016-03-09 published PLOS One Dataset Study consortium Other public 11 3 GlaxoSmithKline Medical Research Council Dataset Quantitative en Data record - Figshare https://figshare.com/collections/Validation_of_the_Recording_of_Acute_Exacerbations_of_COPD_in_UK_Primary_Care_Electronic_Healthcare_Records/2855311 data Publication - PLOS One https://doi.org/10.1371/journal.pone.0151357 dataresource GlaxoSmithKline http://dx.doi.org/10.13039/100004330 Medical Research Council http://dx.doi.org/10.13039/501100000265 2016-03-09