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    <title>UK prevalence of risk factors for severe COVID-19 disease, by age and region: point prevalence estimates in 2019 and 2014, using electronic health records</title>
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      <item>EPAA</item>
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      <item>Prevalence</item>
      <item>Electronic health records</item>
      <item>COVID-19</item>
      <item>Risk factors</item>
      <item>United Kingdom</item>
      <item>Coronavirus</item>
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    <note>This study is based in part on data from the Clinical Practice Research Datalink obtained under licence from the UK Medicines and Healthcare products Regulatory Agency. The data is provided by patients and collected by the NHS as part of their care and support. The interpretation and conclusions contained in this study are those of the author/s alone.</note>
    <abstract>This dataset presents prevalence estimates for the population at higher risk of severe COVID-19 and each underlying health condition, for each of the four nations in the United Kingdom.

Conditions are those included in June 2020 UK guidance (https://web.archive.org/web/20200716054208/https://www.nhs.uk/conditions/coronavirus-covid-19/people-at-higher-risk/whos-at-higher-risk-from-coronavirus/), and, separately survivors of cancer.

Estimates are presented as prevalence /100,000 population with 95% confidence intervals, stratified by age and region (separately and in combination) on each of 5 March 2019 and 5 March 2014.

The point prevalence of pregnancy is additionally provided for 5 March 2014, stratified by age and region.

Main estimates are based on primary care records for  2.7 million eligible individuals in 2019 and 4.7 million in 2014, from the Clinical Practice Research Datalink https://www.cprd.com/ 

For England, prevalence estimates supplemented with secondary care record data are also provided for 2014 and 2019, stratified by age and region.

Please note the 2019 estimates do not include any individuals from the North East or East Midlands regions of England. Estimates for 2014 cover all regions across England.

Values smaller than five are suppressed for confidentiality.

Approval was received from the Independent Scientific Advisory Committee of the Medicines and Healthcare Products Regulatory Agency (ISAC number: 20_062A) and the Ethics Committee of the London School of Hygiene and Tropical Medicine (reference number: 21851).</abstract>
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    <place_of_pub>London, United Kingdom</place_of_pub>
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    <collection_method>Analysis of electronic health records from the Clinical Practice Research Datalink https://www.cprd.com/</collection_method>
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