Supplement to: "Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea" – Data Codebook

Persistent identifier

10.17037/DATA.00000766

Description

Anonymised dataset supporting the Lancet Global Health paper, “Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea".

Codebook

The dataset contains 15 variables.

Variable name Variable description Answer code Answer label Variable type
country Country name     String
    Ghana Ghana  
    PNG Papua New Guinea  
age Participant age Open ended   Numeric
sex Participant sex     String
    Female Female  
    Male Male  
    0 Not recorded  
lesiontype Lesion type     String
    Papillomata Papillomata  
    Ulcer Ulcer  
    0 Not recorded  
arm Trial arm to which participant was assigned     String
    30mg Treatment with 30 mg/kg  
    20mg Treatment with 20 mg/kg  
    Not Randomised Not Randomised  
TPPCR Treponema pallidum Polymerase Chain Reaction (TP-PCR)     Numeric
    0 Negative  
    1 Positive  
HDPCR Haemophilus ducreyi Polymerase Chain Reaction (HD-PCR)     Numeric
    0 Negative  
    1 Positive  
lesion4 Status of skin lesion healing at 4 weeks     String
    Completely healed Completely healed  
    Partially healed Partially healed  
    No improvement No improvement  
    Data at 4wks missing Missing data at 4 weeks  
    Lost Lost to followup  
    0 Not recorded  
rprquan0 Rapid Plasma Reagin (RPR) test - titre 0     Numeric
rprquan6 Rapid Plasma Reagin (RPR) test - titre 6     Numeric
reason_not_rand Reason participant was not randomised     String
    Randomised Participant was randomised  
    T1 neg T1 negative  
    T2 neg T2 negative  
    T1&T2 neg T1 and T2 negative  
    T1 or T2 missing T1 or T2 missing  
    Unwell at sceening Unwell at screening  
    Unable to take blood Unable to take blood  
    Unknown reason Unknown reason  
hd_tp Treponema pallidum (TP) and Haemophilus ducreyi (HD) result     String
    TP- HD- TP Negative, HP negative  
    TP- HD+ TP Negative, HP positive  
    TP+ HD- TP positive, HP negative  
    TP+ HD+ TP positive, HP positive  
    0 Not recorded  
excluded Reason for participant exclusion     String
    4 Week Lesion Data Mission 4 week Lesion data mission  
    Included in Primary Analysis Included in Primary Analysis  
    Missing 6 Month Follow-up RPR Missing 6 Month Follow-up RPR  
    Missing Baseline PCR Missing Baseline PCR  
    Missing Basline RPR Missing Baseline RPR  
    Negative RPR at baseline Negative RPR at baseline  
    Patient did not meet trial inclusion criteria Patient did not meet trial inclusion criteria  
lesion_location Lesion location on body     String
    Arm Arm  
    Back Back  
    Face/Neck Face/Neck  
    Leg Leg  
    Missing Missing  
    Trunk Trunk  
overalloutcome Overall outcome     String
    Clinical Cure & Serological Cure Clinical cure AND Serological Cure  
    Clinical Cure & Non-Significant RPR Change Clinical cure AND non-significant RPR change  
    Clinical Failure & Non-Significant RPR Change Clinical failure AND non-significant RPR change  
    Clinical Failure BUT Serological Cure Clinical failure BUT serological cure  
    Clinical Cure BUT Serological Failure Clinical cure BUT Serological failure  
    Exlcuded from Primary Analysis Excluded from primary analysis