10.17037/DATA.264
This dataset contains the details of the input secondary data sources, methods and results for the global estimates of the birth prevalence of neural tube defects at a global and regional level.
The NTD_input dataset contains the following variables.
| inclusion | To include in final dataset | Numeric | ||
| Yes | 1 | |||
| Null | . | |||
| imputation | Pre-input imputations undertaken | Numeric | ||
| no | 0 | |||
| yes | 1 | |||
| source | Source from which data located | Numeric | ||
| new lit review | 1 | |||
| Atta | 2 | |||
| Zaganjor | 3 | |||
| Lo | 4 | |||
| snowball | 5 | |||
| registry umbrella | 6 | |||
| use_reported | Country data to use as reported | Numeric | ||
| No | 0 | |||
| Yes | 1 | |||
| author | Author or umbrella registry | Open ended | String | |
| prog_name | Name of individual registry if relevant | Open ended | String | |
| year | Year of publication | Open ended | Numeric | |
| study_yr | Year(s) of data collection | Open ended | String | |
| country | Country | Open ended | String | |
| iso3 | Country ISO3 code | Open ended | String | |
| pop_based | Hospital or population based | Numeric | ||
| population based | 1 | |||
| hospital based | 2 | |||
| unclear | 3 | |||
| country_place | Location of study in country | Open ended | String | |
| pct_nat_births | Percentage of national births covered by the study/registry | Open ended | Numeric | |
| birth_ntd | Reports number of affected babies or number of defects | Numeric | ||
| Births - using EUROCAT hierachy for multiple NTDs | 1 | |||
| Births using ICBDSR hierachy for multiple NTDs | 2 | |||
| not clear | 3 | |||
| NTDs - not births | 4 | |||
| Births - unclear hierachy | 5 | |||
| pop_included | Population included from eTOPFA, stillbirths and livebirths | Numeric | ||
| Livebirths only | 1 | |||
| Livebirths and stillbirths | 2 | |||
| Livebirths, stillbirths and eTOPFA at any gestation | 3 | |||
| Livebirths, stillbirths and eTOPFA after 28 weeks) | 4 | |||
| stillbirths only | 5 | |||
| sb_def | Definition used for stillbirth | Open ended | String | |
| cond_included | Range of NTDs included | Numeric | ||
| spina bifida, encephalocoele, anencephaly | 1 | |||
| Spina Bifida only | 2 | |||
| Anencephaly only | 3 | |||
| Spina bifida and anencephaly | 4 | |||
| ffa_mandatory | Status and year of mandatory folic fortification | String | ||
| Not mandated | No | |||
| Year of mandate | YYYY | |||
| report_cov_pnd | Reported coverage of PND in data source | Open ended | String | |
| top_legal | Reported stats of eTOPFA in data source | Open ended | String | |
| asc_method | Method used for ascertainment of cases where stated | Open ended | String | |
| pop_top | Total number of eTOPFA in population | Open ended | Numeric | |
| pop_sb | Total number of stillbirths in population | Open ended | Numeric | |
| pop_lb | Total number of livebirths in population | Open ended | Numeric | |
| pop_tb | Total number of total births (Live and stillbirths) in population | Open ended | Numeric | |
| sp_top | Number of eTOPFA for spina bifida | Open ended | Numeric | |
| sp_sb | Number of stillbirths with spina bifida | Open ended | Numeric | |
| sp_lb | Number of livebirths with spina bifida | Open ended | Numeric | |
| sp_tot | Total number of eTOPFA, stillbirths and livebirths with spina bifida | Open ended | Numeric | |
| enc_top | Number of eTOPFA for encephalocoele | Open ended | Numeric | |
| enc_sb | Number of stillbirths with encephalocoele | Open ended | Numeric | |
| enc_lb | Number of livebirths with encephalocoele | Open ended | Numeric | |
| enc_tot | Total number of eTOPFA, stillbirths and livebirths with encephalocoele | Open ended | Numeric | |
| an_top | Number of eTOPFA for anencephaly | Open ended | Numeric | |
| an_sb | Number of stillbirths with anencephaly | Open ended | Numeric | |
| an_lb | Number of livebirths with anencephaly | Open ended | Numeric | |
| an_tot | Total number of eTOPFA, stillbirths and livebirths with anencephaly | Open ended | Numeric | |
| all_top | Number of eTOPFA for NTDs | Open ended | Numeric | |
| all_sb | Number of stillbirths with NTDs | Open ended | Numeric | |
| all_lb | Number of livebirths with NTDs | Open ended | Numeric | |
| all_tot | Total number of eTOPFA, stillbirths and livebirths with NTDs | Open ended | Numeric | |
| ffa_effect | Folic fortification at effective levels and coverage at time of study | Numeric | ||
| No | 0 | |||
| Yes | 1 | |||
| all_tot_unadj | All Total Unadjusted | Open ended | Numeric | |
| sbr | Estimated stillbirth rate | Open ended | Numeric | |
| whoname | Country WHO name | Open ended | String | |
| UN_subregion | UN subregion coordinates | Open ended | String | |
| UNICEF | UNICEF office | String | ||
| Central & Eastern Europe (CEE) and the Commonwealth of Independent States (CIS) | CEECIS | |||
| East Asia and Pacific Regional Office | EAPRO | |||
| Energy Automation Products & Research Organization | ESARO | |||
| Industrialized | Industrialized | |||
| Middle East and North Africa | MENA | |||
| Regional Office for South Asia | ROSA | |||
| Latin America and the Caribbean Regional Office | TACRO | |||
| West and Central Africa Office | WCARO | |||
| WHO | World Health Organization regions | String | ||
| African Region | AFRO | |||
| Regions of the Americas | AMRO | |||
| Eastern Mediterranean Region | EMRO | |||
| European Region | EURO | |||
| South-East Asian Region | SEARO | |||
| Western Pacific Region | WPRO | |||
| MDG | MDG | String | ||
| Caucasus and Central Asia | Caucasus and Central Asia | |||
| Developed regions | Developed regions | |||
| Eastern Asia | Eastern Asia | |||
| Latin America & the Caribbean | Latin America & the Caribbean | |||
| Northern Africa | Northern Africa | |||
| Oceania | Oceania | |||
| South-eastern Asia | South-eastern Asia | |||
| Southern Asia | Southern Asia | |||
| Sub-Saharan Africa | Sub-Saharan Africa | |||
| Western Asia | Western Asia | |||
| WB | WB | String | ||
| East Asia & Pacific | ||||
| Europe & Central Asia | ||||
| Latin America & Caribbean | ||||
| Middle East & North Africa | ||||
| North America | ||||
| South Asia | ||||
| Sub-Saharan Africa | ||||
| wb_income | WB income range | String | ||
| Low income | ||||
| Lower middle income | ||||
| Upper middle income | ||||
| High income | ||||
| prev_ntd | prev_ntd (Neural tube defects) | Open ended | Numeric | |
| low_prev | low_prev | Open ended | Numeric | |
| up_prev | up_prev | Open ended | Numeric | |
| region | Region ID | Open ended | Numeric | |
| region2 | UN sub-regions combined | Numeric | ||
| Australasia and Oceania | 1 | |||
| Latin America and the Caribbean | 2 | |||
| Eastern Europe and Central Asia | 3 | |||
| sub_Saharan Africa | 4 | |||
| East Asia | 5 | |||
| Northern Africa and Western Asia | 6 | |||
| Europe | 7 | |||
| SE Asia | 8 | |||
| North America | 9 | |||
| Southern Asia | 10 | |||
| imr | Infant Mortality Rate (IMR) | Open ended | double | |
| nlb | Number of livebirths nationally in 2015 | Open ended | long | |
| pop_f | Population F - coefficient of consanguinity | Open ended | double | |
| prop_access | Estimated proportion of the population with access, adjusted IMR-2 (consangX2 an | Open ended | double | |
| u5mr | Number of NTD-related under-5 child mortality (u5mr) | Open ended | double | |
| nmr | Neonatal Mortality Rate (NMR) | Open ended | double | |
| ffa_2015 | Folic acid fortification status in 2015 | String | ||
| No data | ||||
| No fortification | ||||
| Voluntary | ||||
| No FA fortification | ||||
| Planned not implemented 2015 | ||||
| Mandatory not implemented | ||||
| Mandatory | ||||
| ffa_start | Year of introduction of mandatory fortification | Open ended | Integer | |
| Wheat | Wheat | Open ended | String | |
| Maize | Maize | Open ended | String | |
| ffa_mgday | Estimated FA consumption from fortification mg/day | Open ended | double | |
| ffa_cov | Estimated coverage of ffa programme | Open ended | double | |
| est_red_ntd | Estimated % reduction in FA sensitive malformations | Open ended | double | |
| near_neighbour | Basis for near neighbour assumption | Open ended | String | |
| etopfa | Legal status/ practice for eTOPFA | Numeric | ||
| Not legal. No evidence of widespread practice | 0 | |||
| Legal | 1 | |||
| No data | 2 | |||
| Not legal, but evidence of widespread practice | 3 | |||
| Legal for maternal mental health but not eTOPFA directly | 4 |