Data for “The TIGHT-K Trial: Prevention of dysrhythmias on the cardiac intensive care unit - does maintenance of high-normal serum potassium levels matter?” – Data Codebook

Persistent identifier

10.17037/DATA.00005309

Description

An anonymised dataset of 1685 coronary artery bypass graft (CABG) surgery patients, who consented for their data to be shared for the TIGHT K Randomised Controlled Trial (RCT). The purpose of this trial was to determine whether supplementing potassium when serum concentration falls below 3.6mEq/l is noninferior to supplementation when serum concentration falls below 4.5mEq/ for the prevention of atrial fibrillation after cardiac surgery (AFACS).

This multi-centre trial includes data on baseline characteristics, procedural data (CABG), and follow-up data.

Data access conditions

The research has been conducted in accordance with the UK Policy Framework for Health and Social Care Research. Fully anonymized data may be shared for use in health and care research, subject to evidence of ethics approval being provided and a data transfer agreement signed.

Data Codebook

This item is comprised of two datasets

TK Archive Corrected Period data

This dataset contains eight (8) variables related to potassium data only. This dataset is structured differently to the primary data, with multiple rows per patient.

Variable Name Variable Label Answer Label Answer Code Variable Type
uid Patient ID Open ended   Numeric
IndicateBloodGasLabOrPointofCare Potassium measurements     String
    Blood Gas (B) Blood Gas (B)  
    Lab (L) Lab (L)  
    Point of Care (P) Point of Care (P)  
Value Potassium measurement value. mmol/L. Number to 1 decimal place Open ended   Numeric
PotassiumGiven Potassium given? Potassium measurements     String
    No No  
    Yes Yes  
IfYesConfirmTypeGivenIvOralFoodO If yes, confirm type given. Potassium measurements     String
    IV IV  
    Food Food  
    Nasogastric feeding Nasogastric feeding  
    Oral Oral  
    Not recorded .  
WasARedBloodCellTransfusionGiven Was a red blood cell transfusion given? Potassium measurements     String
    No No  
    Yes Yes  
k_period K+ period 1-5 (cleaned) Open ended   Numeric
number_k_measure Sequence number of K+ reading Open ended   Numeric

TK Archive dataset

This is the primary dataset produced as part of the trial. It contains a total of 329 variables, outlined below.

Variable Name Variable Label Answer Label Answer Code Variable Type
uid Patient ID Open ended   Numeric
site Site Open ended   Numeric
arm Arm     String
      Tight  
      Relaxed  
withdrew_elapsed_days_rand Day withdrew-elapsed days since randomisation Open ended   Numeric
withdrew_elapsed_days_icu Day withdrew-elapsed days since admitted to ICU Open ended   Numeric
Sex Sex     String
      Female  
      Male  
Weight Weight (kg) Open ended   Numeric
Height Height (cm) Open ended   Numeric
Bmi BMI (kg/m²) Open ended   Numeric
SystolicBloodPressure Systolic blood pressure (mmHg) Open ended   Numeric
DiastolicBloodPressure Diastolic blood pressure (mmHg) Open ended   Numeric
HeartRate Heart rate (bpm) Open ended   Numeric
AnginaStatusCcs Angina status (CCS)     String
    No angina 0  
    No limitation of physical activity 1  
    Slight limitation of ordinary activity 2  
    Marked limitation of ordinary physical activity 3  
    Symptoms at rest or minimal activity 4  
    Not Known Not Known  
NyhaClass NYHA class     String
    No limitation of physical activity I  
    Slight limitation of physical activity II  
    Marked limitation of physical activity III  
    Symptoms of heart failure at rest IV  
    Not Known Not Known  
SmokingHistory Smoking history     String
    Current smoker Current  
    Ex smoker Ex  
    Never smoked Never  
AlcoholConsumption Alcohol consumption (units per week) Open ended   Numeric
EuroscoreIiValue euroSCORE (%) Open ended   Numeric
Hypertension Hypertension     String
    Yes Yes  
    No No  
    Not documented Not documented  
Hypercholesterolemia Hypercholesterolemia     String
    Yes Yes  
    No No  
    Not documented Not documented  
VascularDisease Vascular disease (other than CAD)     String
    Yes Yes  
    No No  
    Not documented Not documented  
ChronicKidneyDisease Chronic kidney disease     String
    Yes Yes  
    No No  
    Not documented Not documented  
DiabetesMellitus Diabetes mellitus     String
    Yes Yes  
    No No  
    Not documented Not documented  
TypeOfDiabetes If Yes, type of Diabetes     String
    Type I Type I  
    Type II Type II  
    Not documented Not documented  
ImmediateFamilyHistoryOfAF Immediate family history of atrial fibrillation, atrial flutter or atrial tachyc     String
    Yes Yes  
    No No  
    Not documented Not documented  
PreviousCerebrovascularEvent Previous cerebrovascular event     String
    Yes Yes  
    No No  
    Not documented Not documented  
Tia If Yes: TIA (transient ischaemic attack)     String
    Yes Yes  
    No No  
    Not documented Not documented  
Stroke If Yes: Stroke     String
    Yes Yes  
    No No  
    Not documented Not documented  
PreviousMyocardialInfarction Previous Myocardial Infarction     String
    Yes Yes  
    No No  
    Not documented Not documented  
PreviousPci Previous Percutaneous Coronary Intervention (PCI)     String
    Yes Yes  
    No No  
    Not documented Not documented  
CongestiveCardiacFailure Congestive Cardiac Failure     String
    Yes Yes  
    No No  
    Not documented Not documented  
LVMethodUsed LV function Method used     String
    Echocardiogram Echocardiogram  
    MRI MRI  
    Other Other  
RightVentricularImpairment Right ventricular impairment     String
    Yes Yes  
    No No  
    Not documented Not documented  
MitralValveDisease Mitral Valve disease (moderate/severe)     String
    Yes Yes  
    No No  
    Not documented Not documented  
TricuspidValveDisease Tricuspid Valve disease (moderate/severe)     String
    Yes Yes  
    No No  
    Not documented Not documented  
LeftAtrialSize Left atrial size     String
    Yes Yes  
    No No  
    Not documented Not documented  
Copd Chronic Obstructive Pulmonary Disease (COPD)     String
    Yes Yes  
    No No  
    Not documented Not documented  
Asthma Asthma     String
    Yes Yes  
    No No  
    Not documented Not documented  
Hypothyroid Hypothyroid     String
    Yes Yes  
    No No  
    Not documented Not documented  
CirrhosisLiverDisease Cirrhosis / liver disease     String
    Yes Yes  
    No No  
    Not documented Not documented  
HasThePatientHadCovid19 Patient had COVID-19     String
    Yes - positive test result Yes - positive test result  
    Yes - based on symptoms alone Yes - based on symptoms alone  
    No No  
    Not sure Not sure  
PotassiumValue Potassium (mmol/L) Open ended   Numeric
HbValue Haemoglobin (g/L) Open ended   Numeric
CrValue Creatinine(µmol/L) Open ended   Numeric
EGFRValue Estimated GFR (ml/min/1.73m2) Open ended   Numeric
EGRFValue_non_numeric EGRF Non Numeric value     String
    More than 90 >90  
INRValue International Normalised Ratio (INR) blood test Open ended   Numeric
CrpValue C-Reactive Protein (mg/L) Open ended   Numeric
CrpValue_non_numeric C-Reactive Protein     String
    Less than 0.5 <0.5  
    Less than 5 <5  
Antiplatelets Antiplatelets     String
    Yes Yes  
    No No  
    Not Known Not Known  
Bblocker Beta Blockers     String
    Yes Yes  
    No No  
    Not Known Not Known  
AceInhibitors ACE Inhibitors     String
    Yes Yes  
    No No  
    Not Known Not Known  
AngiotensinReceptorBlockers Angiotensin Receptor Blockers     String
    Yes Yes  
    No No  
    Not Known Not Known  
CalciumChannelBlockers Calcium Channel Blockers     String
    Yes Yes  
    No No  
    Not Known Not Known  
Insulin Insulin - Anti-Diabetic Drugs     String
    Yes Yes  
    No No  
    Not Known Not Known  
Tablets Tablets - Anti-Diabetic Drugs     String
    Yes Yes  
    No No  
    Not Known Not Known  
DietControlled Diet controlled - Anti-Diabetic Drugs     String
    Yes Yes  
    No No  
    Not Known Not Known  
FchannelInhibitors f-channel inhibitors - f-channel inhibitors     String
    Yes Yes  
    No No  
    Not Known Not Known  
SGLT2Inhibitors SGLT-2 inhibitors - SGLT-2 inhibitors     String
    Yes Yes  
    No No  
    Not Known Not Known  
NoacsDoacsNotNsaids NOACs/DOACs (not NSAIDS) - Oral Anticoagulants     String
    Yes Yes  
    No No  
    Not Known Not Known  
Warfarin Warfarin - Oral Anticoagulants     String
    Yes Yes  
    No No  
    Not Known Not Known  
ThiazideDiuretics Thiazide Diuretics - Diuretics     String
    Yes Yes  
    No No  
    Not Known Not Known  
AldosteroneAntagonist Aldosterone Antagonist - Diuretics     String
    Yes Yes  
    No No  
    Not Known Not Known  
LoopDiuretics Loop Diuretics - Diuretics     String
    Yes Yes  
    No No  
    Not Known Not Known  
OtherDiuretics Other - Diuretics     String
    Yes Yes  
    No No  
    Not Known Not Known  
AntianginalDrugs Antianginal drugs     String
    Yes Yes  
    No No  
    Not Known Not Known  
Statins Statins     String
    Yes Yes  
    No No  
    Not Known Not Known  
Mobility_baseline Please select ONE option that best describes your health TODAY - Mobility     String
    I have no problems in walking about I have no problems in walking about  
    I have slight problems in walking about I have slight problems in walking about  
    I have moderate problems in walking about I have moderate problems in walking about  
    I have severe problems in walking about I have severe problems in walking about  
    I am unable to walk about I am unable to walk about  
Selfcare_baseline Please select ONE option that best describes your health TODAY - Self-care     String
    I have no problems washing or dressing myself I have no problems washing or dressing myself  
    I have slight problems washing or dressing myself I have slight problems washing or dressing myself  
    I have moderate problems washing or dressing myself I have moderate problems washing or dressing myself  
    I have severe problems washing or dressing myself I have severe problems washing or dressing myself  
    I am unable to wash or dress myself I am unable to wash or dress myself  
UsualActivities_baseline Please select ONE option that best describes your health TODAY - Usual Activitie     String
    I have no problems doing my usual activities I have no problems doing my usual activities  
    I have slight problems doing my usual activities I have slight problems doing my usual activities  
    I have moderate problems doing my usual activities I have moderate problems doing my usual activities  
    I have severe problems doing my usual activities I have severe problems doing my usual activities  
    I am unable to do my usual activities I am unable to do my usual activities  
PainDiscomfort_baseline Please select ONE option that best describes your health TODAY - Pain/Discomfort     String
    I have no pain or discomfort I have no pain or discomfort  
    I have slight pain or discomfort I have slight pain or discomfort  
    I have moderate pain or discomfort I have moderate pain or discomfort  
    I have severe pain or discomfort I have severe pain or discomfort  
    I have extreme pain or discomfort I have extreme pain or discomfort  
AnxietyDepression_baseline Please select ONE option that best describes your health TODAY - Anxiety/Depress     String
    I am not anxious or depressed I am not anxious or depressed  
    I am slightly anxious or depressed I am slightly anxious or depressed  
    I am moderately anxious or depressed I am moderately anxious or depressed  
    I am extremely anxious or depressed I am extremely anxious or depressed  
    I am severely anxious or depressed I am severely anxious or depressed  
YourHealthToday_baseline Your health today - Health score. Number (up to 3 digits) Open ended   Numeric
adm_hospital_elapsed_days_rand Day admitted to hospital-elapsed days since randomisation Open ended   Numeric
adm_hospital_elapsed_days_icu Day admitted to hospital-elapsed days since admitted to ICU Open ended   Numeric
surgery_elapsed_days_rand Day of surgery-elapsed days since randomisation Open ended   Numeric
surgery_elapsed_days_icu Day of surgery-elapsed days since admitted to ICU Open ended   Numeric
WasIsolatedCabgSurgeryPerformed Was isolated CABG surgery performed as planned? - CABG     String
    No No  
    Yes Yes  
Ima Internal Mammary Artery (IMA) - Coronary Artery Bypass Graft (CABG)     String
    No No  
    Yes Yes  
NumberOfGrafts Number of grafts - CABG (up to 2 digits) Open ended   Numeric
PumpStatus Pump status - CABG     String
      On pump  
      Off pump  
BypassDurationInMinutes Bypass duration in minutes - CABG (Number up to 3 digits) Open ended   Numeric
CrossclampDurationInMinutes Cross-clamp duration in minutes - CABG. mins. Number (up to 3 digits) Open ended   Numeric
FurtherBypassRuns Further bypass runs - CABG     String
    No No  
    Yes Yes  
MoreThan30SecondsAtrialFibrilla More than 30 seconds Atrial Fibrillation (during surgery)     String
    No No  
    Yes Yes  
OtherComplications Other complications - Atrial Fibrillation/other complications     String
    No No  
    Yes Yes  
OtherComplicationsWoundInfectio Other complications - Wound infection? - Atrial Fibrillation/other complications     String
    No No  
    Yes Yes  
OtherComplicationsBleeding Other complications - Bleeding? - Atrial Fibrillation/other complications     String
    No No  
    Yes Yes  
OtherComplicationsStroke Other complications - Stroke? - Atrial Fibrillation/other complications     String
    No No  
    Yes Yes  
OtherComplicationsOther Other complications - Other - Atrial Fibrillation/other complications     String
    No No  
    Yes Yes  
Cardioplegia Cardioplegia     String
    No No  
    Yes Yes  
IfYesWhatTypeOfCardioplegia If yes, what type of cardioplegia? - Cardioplegia     String
    Cold blood Cold blood  
    Warm blood Warm blood  
    Crystalloid Crystalloid  
IsPotassiumConcentrationAvailabl Is the potassium concentration coming off bypass data available? - Cardioplegia     String
    No No  
    Yes Yes  
IfYesPotassiumConcentration If yes, what was the potassium concentration coming off bypass - Cardioplegia     Numeric
    No No  
    Yes Yes  
Alive_post_surgery Is the patient alive? - Post surgery     String
    No No  
    Yes Yes  
randomised_elapsed_days_icu Day admitted to ICU-elapsed days since randomisation Open ended   Numeric
startP1_elapsed_days_rand Start day Period 1 - elapsed days since randomisation Open ended   Numeric
startP1_elapsed_days_icu Start day Period 1 - elapsed days since admitted to ICU Open ended   Numeric
StartTimeOfPeriod1 Start time of period 1 - Start and End times for Period 1. 24 hour clock hh:mm Open ended   String
CardiacPacingWiresInPlace_p1 Cardiac pacing - wire(s) in place? - Cardiac pacing     String
    No No  
    Yes Yes  
IfYesIsPacingBoxSwitchedOn_p1 If yes, is pacing box switched on? - Cardiac pacing     String
    No No  
    Yes Yes  
Resternotomy_p1 Resternotomy - Cardiac pacing     String
    No No  
    Yes Yes  
CardioversionChemical_p1 Cardioversion - Chemical - Cardiac pacing     String
    No No  
    Yes Yes  
TakeBackToSurgery_p1 Take-back to surgery? - Cardiac pacing     String
    No No  
    Yes Yes  
IfYesGiveReasonsBleeding_p1 If yes, give reason(s) - bleeding? - Cardiac pacing     String
    No No  
    Yes Yes  
WerePotassiumLoweringOrSpar_p1 Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsIv_p1 Potassium lowering agents (IV) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsNebul_p1 Potassium lowering agents (nebuliser) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsOral_p1 Potassium lowering agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumSparingAgentsOralMed_p1 Potassium sparing agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
BetaBlockersPrescribedThisPer_p1 Beta blockers prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
AmiodaronePrescribThisPeriod_p1 Amiodarone prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
MagnesiumPrescribThisPeriod_p1 Magnesium prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
SteroidsPrescribedThisPeriod_p1 Steroids prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
CrpValue_p1 CRP value - C-Reactive Protein. mg/L. Number to 1 decimal place     Numeric
    Less than 0.5 <0.5  
    Less than 1 <1  
    Less than 5 <5  
CrpValue_non_numeric_p1 Non Numeric value Open ended   String
startP2_elapsed_days_rand Start day Period 2 - elapsed days since randomisation Open ended   Numeric
startP2_elapsed_days_icu Start day Period 2 - elapsed days since admitted to ICU Open ended   Numeric
StartTimeOfPeriod2 Start time of period 2 - Start and End times for Period 2. 24 hour clock hh:mm Open ended   String
CardiacPacingWiresInPlace_p2 Cardiac pacing - wire(s) in place? Cardiac pacing     String
    No No  
    Yes Yes  
IfYesIsPacingBoxSwitchedOn_p2 If yes, is pacing box switched on? - Cardiac pacing     String
    No No  
    Yes Yes  
Resternotomy_p2 Resternotomy - Cardiac pacing     String
    No No  
    Yes Yes  
CardioversionChemical_p2 Cardioversion - Chemical - Cardiac pacing     String
    No No  
    Yes Yes  
WerePotassiumLoweringOrSpar_p2 Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsIv_p2 Potassium lowering agents (IV) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsNebul_p2 Potassium lowering agents (nebuliser) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsOral_p2 Potassium lowering agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumSparingAgentsOralMed_p2 Potassium sparing agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
BetaBlockersPrescribedThisPer_p2 Beta-blockers prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
AmiodaronePrescribThisPeriod_p2 Amiodarone prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
MagnesiumPrescribThisPeriod_p2 Magnesium prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
SteroidsPrescribedThisPeriod_p2 Steroids prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
CrpValue_p2 CRP value - C-Reactive Protein. mg/L. Number to 1 decimal place Open ended   Numeric
startP3_elapsed_days_rand Start day Period 3 - elapsed days since randomisation Open ended   Numeric
startP3_elapsed_days_icu Start day Period 3 - elapsed days since admitted to ICU Open ended   Numeric
StartTimeOfPeriod3 Start time of period 3 - Start and End times for Period 3. 24 hour clock hh:mm Open ended   String
RenalReplacement_p3 Renal replacement therapy post surgery - Renal replacement therapy     String
    No No  
    Yes Yes  
CardiacPacingWiresInPlace_p3 Cardiac pacing - wire(s) in place? - Cardiac pacing     String
    No No  
    Yes Yes  
IfYesIsPacingBoxSwitchedOn_p3 If yes, is pacing box switched on? - Cardiac pacing     String
    No No  
    Yes Yes  
CardioversionChemical_p3 Cardioversion - Chemical - Cardiac pacing     String
    No No  
    Yes Yes  
WerePotassiumLoweringOrSpar_p3 Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsIv_p3 Potassium lowering agents (IV) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsNebul_p3 Potassium lowering agents (nebuliser) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsOral_p3 Potassium lowering agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumSparingAgentsOralMed_p3 Potassium sparing agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
BetaBlockersPrescribedThisPer_p3 Beta-blockers prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
AmiodaronePrescribThisPeriod_p3 Amiodarone prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
MagnesiumPrescribThisPeriod_p3 Magnesium prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
SteroidsPrescribedThisPeriod_p3 Digoxin prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
CrpValue_p3 CRP value - C-Reactive Protein. mg/L. Number to 1 decimal place Open ended   Numeric
startP4_elapsed_days_rand Start day Period 4 - elapsed days since randomisation Open ended   Numeric
startP4_elapsed_days_icu Start day Period 4 - elapsed days since admitted to ICU Open ended   Numeric
StartTimeOfPeriod4 Start time of period 4 - Start and End times for Period 4. 24 hour clock hh:mm Open ended   String
CardiacPacingWiresInPlace_p4 Cardiac pacing - wire(s) in place? - Cardiac pacing     String
    No No  
    Yes Yes  
IfYesIsPacingBoxSwitchedOn_p4 If yes, is pacing box switched on? - Cardiac pacing     String
    No No  
    Yes Yes  
CardioversionChemical_p4 Cardioversion - DC - Cardiac pacing     String
    No No  
    Yes Yes  
WerePotassiumLoweringOrSpar_p4 Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsIv_p4 Potassium lowering agents (IV) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsNebul_p4 Potassium lowering agents (nebuliser) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsOral_p4 Potassium lowering agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumSparingAgentsOralMed_p4 Potassium sparing agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
BetaBlockersPrescribedThisPer_p4 Beta-blockers prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
AmiodaronePrescribThisPeriod_p4 Amiodarone prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
MagnesiumPrescribThisPeriod_p4 Magnesium prescribed this period? - Medications prescribed this period?     String
    No No  
    Yes Yes  
CrpValue_p4 CRP value - C-Reactive Protein. mg/L. Number to 1 decimal place Open ended   Numeric
startP5_elapsed_days_rand Start day Period 5 - elapsed days since randomisation Open ended   Numeric
startP5_elapsed_days_icu Start day Period 5 - elapsed days since admitted to ICU Open ended   Numeric
StartTimeOfPeriod5 Start time of period 5 - Start and End times for Period 5. 24 hour clock hh:mm Open ended   String
RenalReplacement_p5 Renal replacement therapy post surgery - Renal replacement therapy     String
    No No  
    Yes Yes  
CardiacPacingWiresInPlace_p5 Cardiac pacing - wire(s) in place? - Cardiac pacing     String
    No No  
    Yes Yes  
IfYesIsPacingBoxSwitchedOn_p5 If yes, is pacing box switched on? - Cardiac pacing     String
    No No  
    Yes Yes  
Resternotomy_p5 Resternotomy - Cardiac pacing     String
    No No  
    Yes Yes  
CardioversionChemical_p5 Cardioversion - Chemical - Cardiac pacing     String
    No No  
    Yes Yes  
WerePotassiumLoweringOrSpar_p5 Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsIv_p5 Potassium lowering agents (IV) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsNebul_p5 Potassium lowering agents (nebuliser) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumLoweringAgentsOral_p5 Potassium lowering agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
PotassiumSparingAgentsOralMed_p5 Potassium sparing agents (oral medication) - Were any potassium lowering or sparing agents given during this period?     String
    No No  
    Yes Yes  
BetaBlockersPrescribedThisPer_p5 Beta-blocker prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
AmiodaronePrescribThisPeriod_p5 Amiodarone prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
MagnesiumPrescribThisPeriod_p5 Magnesium prescribed this period? - Medications prescribed this period     String
    No No  
    Yes Yes  
CrpValue_p5 CRP value - C-Reactive Protein. mg/L. Number to 1 decimal place Open ended   Numeric
LastRecordedLocationOfPatient_p5 Location of patient at end of period 5 - Status end period 5     String
    Critical Care Unit CCU  
    Home Home  
    Intensive Therapy Unit/Intensive Care Unit ITU/ICU  
    Ward Ward  
    Other Other  
DuringPeriods15CVA During periods 1-5 did the patient have central venous access? - During periods     String
    No No  
    Yes Yes  
inserted_elapsed_days_rand Day inserted - elapsed days since randomisation Open ended   Numeric
inserted_elapsed_days_icu Day inserted - elapsed days since admitted to ICU Open ended   Numeric
IfKnownWhatTimeWasThisInserted And, if known, what time was this inserted? - During periods 1-5 did the patient Open ended   String
WasTheCentralVenousAccessRemoved Was the central venous access removed during periods 1-5?     String
    No No  
    Yes Yes  
removed_elapsed_days_rand Day removed - elapsed days since randomisation Open ended   Numeric
removed_elapsed_days_icu Day removed - elapsed days since admitted to ICU Open ended   Numeric
AndIfKnownWhatTimeWasThisRemoved And, if known, what time was this removed? - During periods 1-5 did the patient Open ended   String
WasCVAReinsertedDuringPeriods15 Was central venous access reinserted during periods 1-5?     String
    No No  
    Yes Yes  
inserted1_elapsed_days_rand Day reinserted - elapsed days since randomisation Open ended   Numeric
inserted1_elapsed_days_icu Day reinserted - elapsed days since admitted to ICU Open ended   Numeric
IfKnownWhatTimeWasThisInserted1 And, if known, what time was this inserted? - Was central venous access reinsert Open ended   String
WasTheCentralVenousAccessRemove1 Was the central venous access removed during periods 1-5? (first time)     String
    No No  
    Yes Yes  
removed1_elapsed_days_rand Day removed - elapsed days since randomisation Open ended   Numeric
removed1_elapsed_days_icu Day removed - elapsed days since admitted to ICU Open ended   Numeric
AndIfKnownWhatTimeWasThisRemove1 And, if known, what time was this removed? Open ended   String
WasCVAReinsertedAgainDuring Was central venous access reinserted again during periods 1-5?     String
    No No  
    Yes Yes  
discharge_elapsed_days_rand Day of discharge - elapsed days since randomisation Open ended   Numeric
discharge_elapsed_days_icu Day of discharge - elapsed days since admitted to ICU Open ended   Numeric
IfYesWhereDischargedTo If Yes, where discharged to - Is the patient alive?     String
    Home Home  
    Another hospital Another hospital  
    Other Other  
StrokeDuringIndexHospitalisatio Stroke during index hospitalisation - Is the patient alive?     String
    No No  
    Yes Yes  
HeartRate_discharge Heart rate - Heart rate & pulse. bpm. Number (up to 3 digits) Open ended   Numeric
PulseRegular_discharge Pulse regular - Heart rate & pulse     String
    No No  
    Yes Yes  
BetweenEndOfP5AndDischargeAF Between end of period 5 and discharge has the patient experienced AFACS?     String
    No No  
    Yes Yes  
SinusRhythm_discharge Sinus rhythm - Incidence of other clinically significant arrhythmias (Between end of period 5 and discharge has the patient experienced AFACS?)     String
    No No  
    Yes Yes  
    Not known Not known  
NonAFSupraventriTachy_discharge Non-AF supraventricular tachycardia (≥30 seconds)     String
    No No  
    Yes Yes  
    Not known Not known  
VentricularTachyFibr_discharge Ventricular tachycardia/fibrillation (more than 3 beats at >100 bpm) - Incidence     String
    No No  
    Yes Yes  
    Not known Not known  
CompleteHeartBlock_discharge Complete heart block - Incidence of other clinically significant arrhythmias     String
    No No  
    Yes Yes  
    Not known Not known  
AnyUnexpectedAdverseEventsSinceS Have any UNEXPECTED adverse events occurred since surgery?     String
    No No  
    Yes Yes  
Hyperkalaemia_dis Hyperkalaemia (K+ >= 5.5mEq/L) - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
Nausea_dis Nausea - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
LineSiteComplications_dis Line site complications (phlebitis, infection etc) - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
Stroke_dis Stroke - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
ProlongedMechanicalSupport_dis Prolonged mechanical support - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
PostOpDelirium_dis Post-op delirium - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
BloodTransfusion_dis Transfusion of Blood or Blood Products (RBC, FFP or Platelets)     String
    No No  
    Yes Yes  
Pericarditis_dis Pericarditis - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
IntraAorticBalloonPumpInsert_dis Intra-aortic balloon pump insertion - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
UrinaryTractInfection_dis Urinary tract infection - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
UrinaryRetention_dis Urinary retention - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
Constipation_dis Constipation - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
Vomiting_dis Vomiting - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
WoundInfection_dis Wound infection (sternum or donor site) - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
ReturnToTheatreForBleeding_dis Return to theatre for bleeding - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
HeartFailure_dis Heart failure - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
MyocardialInfarction_dis Myocardial infarction - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
NoncardiacChestPain_dis Non-cardiac chest pain - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
PericardialEffusion_dis Pericardial effusion - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
PleuralEffusion_dis Pleural effusion - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
ChestDrainInsertion_dis Chest drain insertion - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
ChestInfectionPneumonia_dis Chest infection (pneumonia) - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
LungAtelectasis_dis Lung atelectasis - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
Pneumothorax_dis Pneumothorax - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
RenalImpairmentNoDialysis_dis Renal impairment not requiring dialysis - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
ShortnessOfBreath_dis Shortness of breath caused by any of the above - Expected Adverse Events (from randomisation till discharge)     String
    No No  
    Yes Yes  
Antiplatelets_dis Antiplatelets - Antiplatelets     String
    No No  
    Yes Yes  
    Not known Not known  
Bblocker_dis B-Blockers     String
    No No  
    Yes Yes  
    Not known Not known  
AceInhibitors_dis ACE Inhibitors     String
    No No  
    Yes Yes  
    Not known Not known  
AngiotensinReceptorBlockers_dis Angiotensin Receptor Blockers     String
    No No  
    Yes Yes  
    Not known Not known  
CalciumChannelBlockers_dis Calcium Channel Blockers     String
    No No  
    Yes Yes  
    Not known Not known  
Insulin_dis Insulin - Anti-Diabetic Drugs     String
    No No  
    Yes Yes  
    Not known Not known  
Tablets_dis Tablets - Anti-Diabetic Drugs     String
    No No  
    Yes Yes  
    Not known Not known  
DietControlled_dis Diet controlled - Anti-Diabetic Drugs     String
    No No  
    Yes Yes  
    Not known Not known  
FchannelInhibitors_dis f-channel inhibitors - f-channel inhibitors     String
    No No  
    Yes Yes  
    Not known Not known  
SGLT2Inhibitors_dis SGLT-2 inhibitors - SGLT-2 inhibitors     String
    No No  
    Yes Yes  
    Not known Not known  
NoacsDoacsNotNsaids_dis NOACs/DOACs (not NSAIDS) - Long-term Oral Anticoagulants     String
    No No  
    Yes Yes  
    Not known Not known  
NoacDoacPrescribedSpecifAF_dis If yes, NOAC/DOAC, was it prescribed specifically because of atrial fibrillation     String
    No No  
    Yes Yes  
    Not known Not known  
Warfarin_dis Warfarin - Long-term Oral Anticoagulants     String
    No No  
    Yes Yes  
    Not known Not known  
ThiazideDiuretics_dis Thiazide Diuretics - Diuretics     String
    No No  
    Yes Yes  
    Not known Not known  
AldosteroneAntagonist_dis Aldosterone Antagonist - Diuretics     String
    No No  
    Yes Yes  
    Not known Not known  
LoopDiuretics_dis Loop Diuretics - Diuretics     String
    No No  
    Yes Yes  
    Not known Not known  
OtherDiuretics_dis Other - Diuretics     String
    No No  
    Yes Yes  
    Not known Not known  
AntianginalDrugs_dis Antianginal drugs     String
    No No  
    Yes Yes  
    Not known Not known  
Amiodarone_dis Amiodarone     String
    No No  
    Yes Yes  
    Not known Not known  
AmiodaronPrescribedSpecifAF_dis If yes, was it prescribed specifically because of atrial fibrillation, atrial flutter or atrial tachycardia?     String
    No No  
    Yes Yes  
    Not known Not known  
PotassiumSupplements_dis Potassium supplements     String
    No No  
    Yes Yes  
    Not known Not known  
Statins_dis Statins     String
    No No  
    Yes Yes  
    Not known Not known  
Critical_care_los Critical care length of stay Open ended   Numeric
Hospital_los Hospital length of stay Open ended   Numeric
IsThePatientAlive_fu6m Patient alive at 6 month follow-up     String
    No No  
    Yes Yes  
collect_fu6m_elapsed_days_rand Day of interview - elapsed days since randomisation Open ended   Numeric
collect_fu6m_elapsed_days_icu Day of interview - elapsed days since admitted to ICU Open ended   Numeric
loc_fu6m Location of patient at 6 months     String
    Home Home  
    Other Other  
    Location unknown Location unknown  
SinceDischargePatientExpAF_fu6m Patient experienced AFACS since discharge     String
    No No  
    Yes Yes  
af_fu6m_elapsed_days_rand Day of AF - elapsed days since randomisation Open ended   Numeric
af_fu6m_elapsed_days_icu Day of AF - elapsed days since admitted to ICU Open ended   Numeric
IfYesStartTime_AF_fu6m If yes, start time - Since discharge has the patient experienced atrial fibrilla Open ended   String
SinusRhythm_fu6m Sinus rhythm     String
    No No  
    Yes Yes  
Doac_fu6m DOAC (treatment commenced since discharge)     String
    No No  
    Yes Yes  
    Not Known Not Known  
meds_AtrialFibSinceCardSurg_fu6m Anticoagulation given for Atrial fibrillation since cardiac surgery     String
    No No  
    Yes Yes  
IfYesIsTheAF_fu6m If yes, was AF     String
    Single episode Single episode  
    Paroxysmal AF (intermittent and recurring) or Persistent Paroxysmal AF (intermittent and recurring) or Persistent  
AnyUnexpectedAdvEvtsSinceD_fu6m Unexpected AE since discharge     String
    No No  
    Yes Yes  
any_exp_ae_fu6m Expected AE since discharge     String
    No No  
    Yes Yes  
Hyperkalaemia_fu6m Hyperkalaemia (K+ >= 5.5mEq/L) - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
Nausea_fu6m Nausea - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
BloodTransfusion_fu6m Transfusion of Blood or Blood Products (RBC, FFP or Platelets) - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
UlnarNerveParaesthesia_fu6m Ulnar nerve paraesthesia - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
HeartBlockRequirPacemaker_fu6m Heart block requiring pacemaker - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
IntraAorticBalloonPumpIns_fu6m Intra-aortic balloon pump insertion - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
UrinaryTractInfection_fu6m Urinary tract infection - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
UrinaryRetention_fu6m Urinary retention - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
Constipation_fu6m Constipation - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
Vomiting_fu6m Vomiting - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
WoundInfection_fu6m Wound infection (sternum or donor site)* - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
HeartFailure_fu6m Heart failure - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
MyocardialInfarction_fu6m Myocardial infarction - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
NoncardiacChestPain_fu6m Non-cardiac chest pain - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
PericardialEffusion_fu6m Pericardial effusion - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
PleuralEffusion_fu6m Pleural effusion - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
ChestDrainInsertion_fu6m Chest drain insertion - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
ChestInfectionPneumonia_fu6m Chest infection (pneumonia) - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
LungAtelectasis_fu6m Lung atelectasis - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
RenalImpairmentNoDialysis_fu6m Renal impairment not requiring dialysis - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
ShortnessOfBreath_fu6m Shortness of breath caused by any of the above - Expected Adverse Events (from discharge till 6 months)     String
    No No  
    Yes Yes  
PatientHaveRecollection_fu6m Patient recalls receiving potassium supplementation during admission     String
    No No  
    Yes Yes  
Mobility_fu6m Please select ONE option that best describes your health TODAY - Mobility     String
    I have no problems in walking about I have no problems in walking about  
    I have slight problems in walking about I have slight problems in walking about  
    I have moderate problems in walking about I have moderate problems in walking about  
    I have severe problems in walking about I have severe problems in walking about  
    I am unable to walk about I am unable to walk about  
Selfcare_fu6m Please select ONE option that best describes your health TODAY - Self-care     String
    I have no problems washing or dressing myself I have no problems washing or dressing myself  
    I have slight problems washing or dressing myself I have slight problems washing or dressing myself  
    I have moderate problems washing or dressing myself I have moderate problems washing or dressing myself  
    I have severe problems washing or dressing myself I have severe problems washing or dressing myself  
    I am unable to wash or dress myself I am unable to wash or dress myself  
UsualActivities_fu6m Please select ONE option that best describes your health TODAY - Usual Activities     String
    I have no problems doing my usual activities I have no problems doing my usual activities  
    I have slight problems doing my usual activities I have slight problems doing my usual activities  
    I have moderate problems doing my usual activities I have moderate problems doing my usual activities  
    I have severe problems doing my usual activities I have severe problems doing my usual activities  
    I am unable to do my usual activities I am unable to do my usual activities  
PainDiscomfort_fu6m Please select ONE option that best describes your health TODAY - Pain/Discomfort     String
    I have no pain or discomfort I have no pain or discomfort  
    I have slight pain or discomfort I have slight pain or discomfort  
    I have moderate pain or discomfort I have moderate pain or discomfort  
    I have severe pain or discomfort I have severe pain or discomfort  
    I have extreme pain or discomfort I have extreme pain or discomfort  
AnxietyDepression_fu6m Please select ONE option that best describes your health TODAY - Anxiety/Depression     String
    I am not anxious or depressed I am not anxious or depressed  
    I am slightly anxious or depressed I am slightly anxious or depressed  
    I am moderately anxious or depressed I am moderately anxious or depressed  
    I am extremely anxious or depressed I am extremely anxious or depressed  
    I am severely anxious or depressed I am severely anxious or depressed  
YourHealthToday_fu6m Your health today - Health score. Number (up to 3 digits) Open ended   Numeric
eq5d_fu6m ed5d completed at six month follow up     Numeric
    No 0  
    Yes 1  
BrainImaging1 Brain imaging performed     String
    No 0  
    Yes Brain imaging performed  
StrokeDiagnosis1 1 StrokeDiagnosis     String
  Is the question 'has a stroke been diagnosed?' (it seems to relate to p52) No 0  
    Yes Stroke  
StrokeDiagnosedDuringIndexHos1 Was stroke diagnosed during the index hospitalisation?     String
      Yes  
stroke_elapsed_days_rand Day of stroke - elapsed days since randomisation Open ended   Numeric
stroke_elapsed_days_icu Day of stroke - elapsed days since admitted to ICU Open ended   Numeric
WasPrimaryCauseOfDeath Primary cause of death     String
    Cardiovascular death Cardiovascular death  
    Other/unknown Other/unknown  
death_elapsed_days_rand Day of death - elapsed days since randomisation Open ended   Numeric
death_elapsed_days_icu Day of death - elapsed days since admitted to ICU Open ended   Numeric
euros_cat euroscore as category     String
      Low risk  
      Medium risk  
      High risk  
age_cat Age as category     String
    Under 62 <62  
    62 to 75 62-75  
    Over 75 >75  
LVEF_cat LVEF as category Open ended   String
    Poor/Severe Poor/Severe  
    Moderate Moderate  
    Good/Normal Good/Normal  
ethnicity_group Ethnicity as category     String
    Asian/Asian British Asian/Asian British  
    Black/Black British Black/Black British  
    White White  
    Other Other  
    Not stated Not stated  
Alive_disharge_yn Alive at discharge     String
    No No  
    Yes Yes  
period_af AFAC period 1-5 cleaned Open ended   Numeric
af_elapsed_days_rand Day of AFAC - elapsed days since randomisation Open ended   Numeric
af_elapsed_days_icu Day of AFAC - elapsed days since admitted to ICU Open ended   Numeric
AFAC_EVC AFAC evaluation     String
    No AFACS No AFACS  
    Probable AFACS Probable AFACS  
    Confirmed AFACS Confirmed AFACS  
afacs Primary outcome - new-onset AFACS in the first 120 hours after CABG     Numeric
    No 0  
    Yes 1  
missing_partial_holter Missing or partial holter data (gaps, inadequate)     Numeric
    No 0  
    Yes 1  
holter_afac_yn AFACs identified on AHRM     String
    No no  
    Yes yes  
non_af_ever Any Non-AF dysrhythmia detected on AHRM     String
    No no  
    Yes yes  
ITT Intention to treat population     String
    Yes Yes  
    No .  
EA Efficacy analysis population (The efficacy analysis reported in the published paper included all participants assigned a randomization number who underwent isolated CABG surgery)     String
    Yes Yes  
PP Per protocol population (The per-protocol analysis in the published paper comprised the efficacy analysis population with the exclusion of participants not completing a protocol-adherent course of treatment)     String
    Yes Yes  
country Country     String
    Germany Germany  
    United Kingdom UK