Search strategy L for: "UK malaria treatment guidelines"


Please refer to the Methods file for details of search methodology and deduplication.

Topic L was simply defined as: Severe falciparum malaria AND (intravenous quinine OR intravenous artesunate) NOT case reports


Embase Classic+Embase

Database name:	Embase Classic + Embase
Database platform:	Ovid
Dates of database coverage:	1947 to 2025 February 03
Date searched:	2025-02-04
Searched by:	JF
Number of hits:	304
EndNote import number:	2
Number of results after deduplication:	141

1	exp Plasmodium falciparum/ or exp malaria falciparum/ or exp cerebral malaria/	62324
2	(falciparum or (severe adj2 malaria*)).ti,ab.	55515
3	or/1-2 [falciparum]	71091
4	artemisinin derivative/	3408
5	artesunate/	7787
6	quinine/ or quinine derivative/	21319
7	(artemisinin* or artesunate or quinine).ti,ab,rn.	40652
8	or/4-7	41594
9	exp intravenous drug administration/	437935
10	(intravenous or drip).ti,ab.	507708
11	or/9-10	814966
12	3 and 8 and 11	1042
13	case report/	3170195
14	12 not 13	758
15	limit 14 to yr="2010 -Current"	311
16	remove duplicates from 15	304


Global Health

Database name:	Global Health
Database platform:	Ovid
Dates of database coverage:	1910 to 2025 Week 05
Date searched:	2025-02-04
Searched by:	JF
Number of hits:	163
EndNote import number:	3
Number of results after deduplication: 29

1	plasmodium falciparum/ or blackwater fever/ or cerebral malaria/ or falciparum malaria/	50123
2	falciparum.ti,ab.	47103
3	(severe adj2 malaria*).ti,ab.	4491
4	or/1-3 [falciparum]	53339
5	artemisinin/	4983
6	artesunate/	2386
7	quinine/	8485
8	(artemisinin* or artesunate or quinine).ti,ab.	17723
9	or/5-8	18068
10	intravenous injection/	10648
11	(intravenous or drip).ti,ab.	56210
12	or/10-11	56621
13	4 and 9 and 12	769
14	case reports/	108278
15	13 not 14	602
16	limit 15 to yr="2010 -Current"	163
17	remove duplicates from 16	163


Medline ALL

Database name:	Medline ALL
Database platform:	Ovid
Dates of database coverage:	1946 to February 03, 2025
Date searched:	2025-02-04
Searched by:	JF
Number of hits:	192
EndNote import number:	1
Number of results after deduplication:	182

1	Plasmodium falciparum/ or exp Malaria, Falciparum/ or malaria, cerebral/	43551
2	falciparum.ti,ab.	43268
3	(severe adj2 malaria*).ti,ab.	5014
4	or/1-3	54522
5	Quinine/ or Artesunate/	8862
6	(quinine or artemisinin* or artesunate).ti,ab.	19494
7	or/5-6	21884
8	exp Administration, Intravenous/	150644
9	(intravenous or drip).ti,ab.	343295
10	or/8-9	419621
11	4 and 7 and 10	599
12	case reports/	2461440
13	case report*.pt.	2461440
14	or/12-13	2461440
15	11 not 14	423
16	limit 15 to yr="2010 -Current"	192
17	remove duplicates from 16	192


Web of Science Core Content

Database name:	Web of Science Core Content
This contains the following databases which were searched simultaneously:
	• Science Citation Index Expanded (SCI-EXPANDED)
	• Social Sciences Citation Index (SSCI)
	• Arts & Humanities Citation Index (AHCI)
	• Conference Proceedings Citation Index - Science (CPCI-S)
	• Conference Proceedings Citation Index - Social Science & Humanities (CPCI-SSH)
	• Emerging Sources Citation Index (ESCI)
Database platform:	Clarivate Analytics Web of Science
Dates of database coverage:
	• SCI-EXPANDED 1970-present
	• SSCI 1970-present
	• AHCI 1975-present
	• CPCI-S 1990-present
	• CPCI-SSH 1990-present
	• ESCI 2019-present
	Data updated 2025-02-02
Date searched:	2025-02-04
Searched by:	JF
Number of hits:	209
EndNote import number:	4
Number of results after deduplication:	40

1: TI=("falciparum" or ("severe" near/2 malaria*)) or AB=("falciparum" or ("severe" near/2 malaria*))				Results: 45992

2: TI=(artemisinin* or "artesunate" or "quinine") or AB=(artemisinin* or "artesunate" or "quinine")				Results: 20575

3: TI=("intravenous" or "drip") or AB=("intravenous" or "drip")				Results: 302014

4: #3 AND #2 AND #1				Results: 392

5: TS=("case report*")				Results: 435739

6: #4 NOT #5				Results: 350

7: #6		Timespan: 2010-01-01 to 2025-12-31		Results: 209

11: #10		Timespan: 2021-01-01 to 2025-12-31		Results: 78