Metadata supporting "Understanding the role of gut microbiome in the relationship between environment, S. mansoni infection and Cardiovascular risk" – Data Codebook

Persistent identifier

10.17037/DATA.00004919

Description

This dataset contains participant information supporting research to investigate the role of gut microbiome differences in explaining the link between helminths, environment and cardiovascular risk in Ugandan populations who live in rural (LaVIISWA metabolic survey) and urban settings (Entebbe urban survey).

Variables include participant's blood pressure, cholesterol concentration, insulin concentration (while fasting), insulin concentration (while fasting), circulating anodic antigen (CAA) status for Schistosoma mansoni infection, and other measurements.

The raw sequence data are held in the Zenodo repository at 10.5281/zenodo.18186512.

Data Codebook

Variable Name Variable Label Answer Label Answer Code Variable Type
sample_id Unique pseudonymised study sample identifier used to link participant metadata with microbiome and metabolomics datasets     String
Novogene_ID Sequencing provider (Novogene UK) sample identifier     String
slabno Internal laboratory sample number     String
setting Study setting     String
    Rural Rural  
    Urban Urban  
CAA_result Circulating anodic antigen (CAA) status for Schistosoma mansoni infection     String
    Positive Positive  
    Negative Negative  
    Not applicable NA  
age Participant age at time of survey (years)     Numeric
sex Biological sex of participant     String
    Female female  
    Male male  
arm Trial intervention arm in the LaVIISWA study     String
    Intensive Intensive  
    Standard Standard  
case Binary S. mansoni infection status used in primary analyses     String
    Positive Positive  
    Negative Negative  
agegp Participant age group category used for analysis     Numeric
    0 to 19 years 1  
    20 to 29 years 2  
    30 to 39 years 3  
    40 years or over 4  
occp Primary occupation of participant     String
    bar/restaurant/lodge owner bar/restaurant/lodge owner  
    boat owner boat owner  
    builder builder  
    carpenter carpenter  
    child (not in school) child (not in school)  
    farmer farmer  
    fish processing fish processing  
    fisherman fisherman  
    fishmonger fishmonger  
    health worker/ drug shop owner health worker/ drug shop owner  
    house wife house wife  
    market vendor market vendor  
    mechanic mechanic  
    other other  
    restaurant/ hotel/ lodge attendant restaurant/ hotel/ lodge attendant  
    shopkeeper shopkeeper  
    student student  
    teacher teacher  
    unemployed unemployed  
sbpnew Systolic blood pressure (mmHg)     Numeric
dbpnew Diastolic blood pressure (mmHg)     Numeric
ht Height (metres)     Numeric
wt Weight (kilograms)     Numeric
wc Waist circumference (centimetres)     Numeric
cholesterol2 Total cholesterol concentration (mmol/L)     Numeric
ldl_c Low-density lipoprotein cholesterol concentration (mmol/L)     Numeric
insulin Fasting insulin concentration (assay-specific units)     Numeric
glucose Fasting blood glucose concentration (mmol/L)     Numeric