10.17037/DATA.00004583
An anonymised dataset of 1,955 paediatric and adult patients with febrile illness in southern Mozambique, who gave informed consent to participate in the prospective observational FIEBRE study between December 2018 and February 2021. Dataset contains variables on biomarker levels in plasma, demographic data, results of basic diagnostic tests and health status data, calculated clinical severity scores, and mortality and other adverse outcomes by day 28 follow-up.
The following variables are contained within the dataset.
| Variable Name | Variable Label | Answer Label | Answer Code | Variable Type |
| id_external | Unlinked patient ID value | Open ended | Numeric | |
| patient_group | Patient group (inpatient/outpatient/adult/child) | Numeric | ||
| Adult inpatient | adult_inpatient | |||
| Adult outpatient | adult_outpatient | |||
| Child inpatient | child_inpatient | |||
| Child outpatient | child_outpatient | |||
| health_centre | Recruiting hospital | String | ||
| Geral José Macamo Hospital | Geral José Macamo Hospital | |||
| Manhiça District Hospital | Manhiça District Hospital | |||
| sex | Sex | String | ||
| Female | female | |||
| Male | male | |||
| age | Age (in years) | Numeric | ||
| fever_days | Fever duration before enrolment | Numeric | ||
| hiv | HIV status | String | ||
| Negative | negative | |||
| Positive | positive | |||
| Not recorded | . | |||
| hiv_group | HIV group | String | ||
| HIV negative | negative | |||
| HIV positive and taking antiretroviral therapy (ART) | positive+ART | |||
| HIV positive - new infection | positive+new_infection | |||
| HIV positive - no antiretroviral therapy (ART) | positive+no_ART | |||
| HIV positive - no information | positive+no_info | |||
| Not recorded | ||||
| mrdt | Result of malaria RDT | String | ||
| Negative | negative | |||
| Positive | positive | |||
| Not recorded | . | |||
| LODS | Lambaréné Organ Dysfunction Score (LODS) at enrolment | Open ended | Numeric | |
| LqSOFA | Liverpool quick Sequential Organ Failure Assessment (LqSOFA) score at enrolment | Open ended | Numeric | |
| EDPEWS | Emergency Department Paediatric Early Warning Score (ED-PEWS) at enrolment | Open ended | Numeric | |
| MEWS | Modified Early Warning Score (MEWS) at enrolment | Open ended | Numeric | |
| qSOFA | Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) at enrolment | Open ended | Numeric | |
| UVA | Universal Vital Assessment (UVA) at enrolment | Open ended | Numeric | |
| length_hosp_stay | Length os hospital stay for inpatients | Open ended | Numeric | |
| hospital_outcome | Hospital outcome for inpatients | String | ||
| Has left hospital | absconded | |||
| Death | death | |||
| Discharged to home | discharge | |||
| Transferred to other health facility | transfer | |||
| Not applicable | NA | |||
| Not recorded | . | |||
| days_to_death | Number of days from day 0 visit to death | Open ended | Numeric | |
| death7 | Did patient die within seven days? (7-day mortality) | String | ||
| No | no | |||
| Yes | yes | |||
| Not completed | . | |||
| death28 | Did patient die within 28 days? (28-day mortality) | String | ||
| No | no | |||
| Yes | yes | |||
| Not completed | . | |||
| revisit28 | For outpatients, seeking further care for the same illness since the patient left the hospital | String | ||
| No | no | |||
| Yes | yes | |||
| Not completed | . | |||
| readmission28 | For outpatients, being readmitted for the same illness since the patient left the hospital | String | ||
| No | no | |||
| Yes | yes | |||
| Not completed | . | |||
| IL6 | Interleukine-6 (IL-6) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| IL8 | Interleukine-8 (IL-8) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| Angpt2 | Angiopoietin-2 (Angpt-2) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| sFlt1 | Soluble fms-like tyrosine kinase-1 (sFlt-1) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| sTREM1 | Soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| sTNFR1 | Soluble tumor necrosis factor receptor (sTNFR1) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| suPAR | Soluble urokinase-type plasminogen activator receptor (suPAR) levels at enrolment (in ng/mL) | Open ended | Numeric | |
| CHI3L1 | Chitinase-3-like protein 1 (CHI3L1) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| PCT | Procalcitonin (PCT) levels at enrolment (in µg/mL) | Open ended | Numeric | |
| CRP | C-reactive protein (CRP) levels at enrolment (in pg/mL) | Open ended | Numeric | |
| lactate | Lactate levels at enrolment (in mmol/L) | Open ended | Numeric |