10.17037/DATA.00004435
A compiled pseudo-anonymised quantitative dataset collected as part of the PrEPVacc registration cohort and trial. The registration cohort was set up to prepare a population of HIV negative individuals at risk of acquiring HIV for possible participation in the PrEPVacc phase IIB HIV prophylactic vaccine and pre-exposure prophylaxis trial. There are two components to this dataset, firstly the cohort dataset that was used to develop a regression model predicting HIV incidence. Secondly, a trial dataset with the participant characteristics that could be entered in the model and utilised for prediction of HIV incidence that could have occurred if participants in the active-controlled PrEP trial component had never been dispensed PrEP. The PrEPVacc trial was conducted at four study sites in Tanzania (2 sites), South Africa, and Uganda. This dataset is as of 31 Jan 2024.
This dataset may be requested for the purpose of research verification and use in academic research, subject to evidence of ethics approval being provided. Data applications are handled by the MRC / UVRI and LSHTM Uganda Research Unit, taking advice from the Research Ethics Committee as needed.
| Variable Name | Variable Label | Answer Label | Answer Code | Variable Type |
| trial | Trial or cohort | Numeric | ||
| Registration cohort | 0 | |||
| Trial | 1 | |||
| Coded_ID | Coded ID | Open ended | String | |
| Coded_Cohort_ID | Registration cohort study number | Open ended | String | |
| site | Study site | Numeric | ||
| Masaka | 1 | |||
| Durban | 2 | |||
| Mbeya | 3 | |||
| Dar es Salaam | 4 | |||
| Verulam | 6 | |||
| enrdate | Enrolment date | Open ended | Numeric | |
| vdate | Last assessment date | Open ended | Numeric | |
| personyears | Person age | Open ended | Numeric | |
| hivrr | Last HIV rapid test result - Regn cohort | Numeric | ||
| Negative | 0 | |||
| Positive | 1 | |||
| Negative | 2 | |||
| Discordant/Indeterminate | 3 | |||
| gender | Gender | Numeric | ||
| Male | 1 | |||
| Female | 2 | |||
| Other | 3 | |||
| Categorised_age | Categorised age (years) at baseline | Numeric | ||
| less than 25 | 1 | |||
| Greater or equal to 25 | 2 | |||
| mstat | Marital status | Numeric | ||
| Single | 1 | |||
| Married | 2 | |||
| Cohabiting | 3 | |||
| In a relationship but not living together | 4 | |||
| Widowed | 5 | |||
| Divorced/separated | 6 | |||
| educ | Highest level of education attained | Numeric | ||
| No formal education | 1 | |||
| Incomplete primary | 2 | |||
| Complete primary | 3 | |||
| Incomplete secondary | 4 | |||
| Complete secondary | 5 | |||
| Technical/vocational school | 6 | |||
| Complete University/College | 7 | |||
| Incomplete University/College | 8 | |||
| rel | Religion | Numeric | ||
| Christian | 1 | |||
| Muslim | 2 | |||
| None | 3 | |||
| Other | 4 | |||
| occcombined | Occupation | Numeric | ||
| Other | 1 | |||
| Sex worker | 2 | |||
| Saloon, bar and lodge_not sex worker | 3 | |||
| Subsistence fisheries | 4 | |||
| drusx2 | Sex after recreational drug use | Numeric | ||
| No | 0 | |||
| Yes | 1 | |||
| stis | In the last 3 months, have you been diagnosed with or received treatment for a an STI | Numeric | ||
| No | 1 | |||
| Yes | 2 | |||
| Don't know/Not sure | 3 | |||
| npart2 | How many persons have you had sex with in the last 3 months | Numeric | ||
| 5 or lower | 1 | |||
| 6 or higher | 2 |