Eosinophilia in returning travellers and migrants from the tropics: Search methodology Search terms After discussion with the project team, four search strategies were compiled in the Ovid Medline database by an experienced information specialist (JF). These search strategies were refined with the project team until the results retrieved reflected the scope of the project. For each search, the agreed Ovid Medline search was adapted for each database to incorporate database-specific syntax and controlled vocabularies. Full details of the search strings used for each database can be found below. Search 1: asymptomatic eosinophilia This search strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to reflect the following concepts: Concept 1: eosinophilia Concept 2: returning travellers, migrants or military personnel Limits: papers published in or with subjects returning to non-Endemic countries The list of non-endemic countries was agreed amongst the project team. Human studies only. Case reports or editorials were removed. English-language only. A previously published search was used as the basis of the search for concept 2. (1) Search 2: diagnosis of relevant pathogens This search strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to search for papers on the following concept: Concept 1: relevant pathogens and clinical conditions. The list of pathogens and conditions was agreed amongst the project team. Limits: Diagnostic studies only. The diagnostic studies search filter published by SIGN was used to limit the results to diagnostic studies only.(2) Human studies only. Comments, editorials, letters or news were removed. English language only. Search 3: treatment based randomised controlled trials of relevant pathogens This search strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to search for papers on the following concept: Concept 1: relevant pathogens and clinical conditions. The list of pathogens and conditions was agreed amongst the project team. Limits: Randomised controlled trials only. The randomised controlled trials search filter published by SIGN was used to limit the results to randomised controlled trials only. (2) Human studies only. Comments, editorials, letters or news were removed. English language only. Search 3a: treatment based randomised controlled trials of eosinophilic meningitis Once screening was complete for search 3, it was realised that relevant RCTs on eosinophilic meningitis were not captured. This search was developed to capture these studies. The strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to search for papers on the following concept: Concept 1: Eosinophilic meningitis Limits: Randomised controlled trials only. The randomised controlled trials search filter published by SIGN was used to limit the results to randomised controlled trials only. (2) Human studies only. Comments, editorials, letters or news were removed. English language only. Search 3b: treatment based randomised controlled trials of cystoisosporiasis Once screening was complete for search 3, it was realised that relevant RCTs on cystoisosporiasis were not captured. This search was developed to capture these studies. The strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to search for papers on the following concept: Concept 1: Cystoisosporiasis Limits: Randomised controlled trials only. The randomised controlled trials search filter published by SIGN was used to limit the results to randomised controlled trials only. (2) Human studies only. Comments, editorials, letters or news were removed. English language only. Search 4: treatment based systematic reviews of relevant pathogens and eosinophilic meningitis Once screening was complete for search 3, it was realised that evidence from systematic reviews was required. This search was developed to capture these studies. The strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to search for papers on the following concept: Concept 1: relevant pathogens and clinical conditions, including eosinophilic meningitis. The list of pathogens and conditions was agreed amongst the project team. Limits: Systematic reviews only. The systematic reviews search filter published by CADTH was used to limit the results to systematic reviews only. (3) Human studies only. English language only. Search 4a: treatment based systematic reviews of cystoisosporiasis Once screening was complete for search 4, it was realised that cystoisosporiasis was not included. This search was developed to capture these studies. The strategy included strings of terms, synonyms and controlled vocabulary terms (where available) to search for papers on the following concept: Concept 1: Cystoisosporiasis Limits: Systematic reviews only. The systematic reviews search filter published by CADTH was used to limit the results to systematic reviews only. (3) Human studies only. English language only. Information Sources Search 1: asymptomatic eosinophilia The following bibliographic databases were searched on 20 December 2021. * Ovid Medline ALL, 1946 to December 17, 2021; * Ovid Embase Classic+Embase, 1947 to December 17, 2021; * Ovid Global Health, 1910 to 2021 week 50; * EBSCOhost CINAHL Complete, complete database to search date; * Wiley Cochrane Central Register of Controlled Trials, Issue 12 of 12, December 2021; * Clarivate Analytics Web of Science Core Collection (all databases searched simultaneously): o Science Citation Index-Expanded, 1970-present; o Social Sciences Citation Index, 1970-present; o Arts & Humanities Citation Index, 1975-present; o Conference Proceedings Citation Index-Science, 1990-present; o Conference Proceedings Citation Index-Social Sciences & Humanities, 1990-present; o Emerging Sources Citation Index, 2015-present; * WHO Global Index Medicus: Western Pacific Region Index Medicus, complete database. The following trials registers were searched on 20 December 2021: * World Health Organization International Clinical Trials Registry Platform, complete database; * ClinicalTrials.gov, complete database. Search 2 and search 3: diagnosis and treatment RCTs of relevant pathogens The following bibliographic databases were searched on 21 December 2021. * Ovid Medline ALL, 1946 to December 20, 2021; * Ovid Embase Classic+Embase, 1947 to December 20, 2021; * Ovid Global Health, 1910 to 2021 week 50; * EBSCOhost CINAHL Complete, complete database to search date; * EBSCOhost Africa-Wide Information, complete database to search date; * Wiley Cochrane Central Register of Controlled Trials, Issue 12 of 12, December 2021; * Clarivate Analytics Web of Science, Science Citation Index Expanded, 1970-present; * Clarivate Analytics Web of Science SciELO, 2002-present; * WHO Global Index Medicus, complete database. The following trials registers were searched on 21 December 2021: * World Health Organization International Clinical Trials Registry Platform, complete database; * ClinicalTrials.gov, complete database. Search 3a: treatment RCTs for eosinophilic meningitis The following bibliographic databases were searched on 05 October 2022. * Ovid Medline ALL, 1946 to October 04, 2022; * Ovid Embase Classic+Embase, 1947 to 2022 October 04; * Ovid Global Health, 1910 to 2022 Week 39; * EBSCOhost CINAHL Complete, complete database to search date; * EBSCOhost Africa-Wide Information, complete database to search date; * Wiley Cochrane Central Register of Controlled Trials, Issue 10 of 12, October 2022; * Clarivate Analytics Web of Science, Science Citation Index Expanded, 1970-present; * WHO Global Index Medicus: Western Pacific Region Index Medicus, complete database. * Clarivate Analytics Web of Science SciELO, 2002-present; * WHO Global Index Medicus, complete database. The following trials registers were searched on 05 October 2022: * World Health Organization International Clinical Trials Registry Platform, complete database; * ClinicalTrials.gov, complete database. Search 3b: treatment RCTs for cystoisospora The following bibliographic databases were searched on 03 November 2022: * Ovid Medline ALL, 1946 to November 02, 2022; * Ovid Embase Classic+Embase, 1947 to 2022 November 02; * Ovid Global Health, 1910 to 2022 Week 43; * EBSCOhost CINAHL Complete, complete database to search date; * EBSCOhost Africa-Wide Information, complete database to search date; * Wiley Cochrane Database of Systematic Reviews, Issue 2 of 12, February 2023; * Clarivate Analytics Web of Science, Science Citation Index Expanded, 1970-present; * Clarivate Analytics Web of Science SciELO, 2002-present; * WHO Global Index Medicus, complete database. The following trials registers were searched on 027 February 2023: * World Health Organization International Clinical Trials Registry Platform (ICTRP), complete database; * ClinicalTrials.gov, complete database. Search 4: treatment SRs for relevant pathogens and eosinophilic meningitis The following bibliographic databases were searched on 03 November 2022. * Ovid Medline ALL, 1946 to November 02, 2022; * Ovid Embase Classic+Embase, 1947 to 2022 November 02; * Ovid Global Health, 1910 to 2022 Week 43; * EBSCOhost CINAHL Complete, complete database to search date; * EBSCOhost Africa-Wide Information, complete database to search date; * Wiley Cochrane Database of Systematic Reviews, Issue 11 of 12, October 2022; * Clarivate Analytics Web of Science, Science Citation Index Expanded, 1970-present; * Clarivate Analytics Web of Science SciELO, 2002-present; * WHO Global Index Medicus, complete database. Search 4a: treatment SRs for cystoisospora The following bibliographic databases were searched on 28 March 2023: * Ovid Medline ALL, 1946 to March 27, 2023; * Ovid Embase Classic+Embase, 1947 to 2023 March 28; * Ovid Global Health, 1910 to 2023 week 12; * EBSCOhost CINAHL Complete, complete database to search date; * EBSCOhost Africa-Wide Information, complete database to search date; * Wiley Cochrane Database of Systematic Reviews, Issue 2 of 12, February 2023; * Clarivate Analytics Web of Science, Science Citation Index Expanded, 1970-present; * Clarivate Analytics Web of Science SciELO, 2002-present; * WHO Global Index Medicus, complete database. Information management All results identified by our searches were imported into EndNote 20 software for duplicate removal. Results from search 1 and search 2, were imported into separate EndNote libraries and duplicates within each search results were removed, but duplicates between different searches were retained. Results from search 3, search 3a and search 3b were imported into the same EndNote library and duplicates removed. Results from search 4 and search 4a were imported into the same EndNote library and duplicates removed. Duplicates were identified and removed using the method described on the London School of Hygiene & Tropical Medicine Library & Archives Service blog. (4) Results were exported from the EndNote 20 libraries to .ris format for upload into screening software. Search strategies This document provides full details of all search strings used for bibliographic databases, with dates and number of references returned and notes explaining any unusual search techniques or syntax. The EndNote 20 import order is provided, as the deduplication technique keeps the first uploaded copy of the reference by default. Search 1: Asymptomatic eosinophilia The search published by Buss et al was used as the basis for the returning travellers and migrants section of the search. (1) Ovid Medline ALL Database name: Medline ALL Database platform: Ovid Dates of database coverage: 1946 to December 17, 2021 Date searched: 20 December 2021 Searched by: JF Number of results: 276 EndNote import order: 1 (Medline) and 3 (Medline In Process) Number of results once duplicates removed: 261 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract IN: author institution address KF: author keyword PT: publication type SH: subject heading word TI: title or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. 1 exp Eosinophilia/ 26000 2 (eosinophili* or hypereosinophili*).ti,ab. 51364 3 or/1-2 56310 4 case reports/ or editorial/ 2821988 5 (case reports or editorial).pt. 2821988 6 (editorial* or (case adj1 (histor* or report* or study or studies))).ti,ab,kf. 642100 7 or/4-6 3041341 8 3 not 7 [EOSINOPHILIA NOT CASE REPORTS OF EDITORIALS] 35589 9 exp Travel/ or Travel Medicine/ 30178 10 Military Personnel/ or Military Medicine/ or Military Deployment/ 63696 11 exp "Emigrants and Immigrants"/ or Missionaries/ 14865 12 "Transients and Migrants"/ 13029 13 Communicable Diseases, Imported/ 518 14 (travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or ((army or navy or armed forces or air force) adj1 personnel) or expat* or missionar* or migrant? or immigrant? or emigrant? or refugee* or asylum or (import* adj2 (infect* or diseas*)) or (visit* adj2 (friend* or family or families or relativ* or relation*)) or vfr).ti,ab,kf. 235683 15 or/9-14 [TRAVELLERS ETC] 281827 16 Armenia/ or Armenia.ti,ab,in. 4925 17 "Georgia (Republic)"/ 1913 18 Yugoslavia/ 9076 19 Kosovo.ti,ab,in. 1714 20 Moldova/ or Moldova.ti,ab,in. 1887 21 Ukraine/ or Ukraine.ti,ab,in. 34800 22 Albania/ or Albania.ti,ab,in. 2656 23 Azerbaijan/ or Azerbaijan.ti,ab,in. 3639 24 "Republic of Belarus"/ or (belarus or byelarus or belorussia).ti,ab,in. 6651 25 Bosnia-Herzegovina/ or (bosnia or herzegovia).ti,ab,in. 6948 26 Bulgaria/ or Bulgaria.ti,ab,in. 23000 27 Hungary/ or hungary.ti,ab,in. 84459 28 "Macedonia (Republic)"/ or Macedonia.ti,ab,in. 5287 29 Montenegro/ or Montenegro.ti,ab,in. 4761 30 Romania/ or Romania.ti,ab,in. 46120 31 Serbia/ or serbia.ti,ab,in. 29535 32 Turkey/ or (turkey.ti,ab,in. not animal/) 257270 33 Andorra/ or andorra.ti,ab,in. 263 34 Croatia/ or croatia.ti,ab,in. 35741 35 Cyprus/ or cyprus.ti,ab,in. 11241 36 Liechtenstein/ or liechtenstein.ti,ab,in. 737 37 Malta/ or Malta.ti,ab,in. 5991 38 Monaco/ or monaco.ti,ab,in. 4411 39 San Marino/ or san marino.ti,ab,in. 335 40 Austria/ or austria.ti,ab,in. 183722 41 Belgium/ or belgium.ti,ab,in. 263469 42 Czech Republic/ or (czechoslovakia or czech republic).ti,ab,in. 96361 43 Denmark/ or (denmark or faeroe islands).ti,ab,in. 259849 44 Sweden/ or sweden.ti,ab,in. 402531 45 exp Norway/ or norway.ti,ab,in. 168813 46 Scandinavia/ or scandinavia.ti,ab. 7328 47 exp Baltic States/ or (Baltic or estonia or latvia or lithuania).ti,ab,in. 38653 48 exp Russia/ or USSR/ or (Russia or Russian Federation or USSR or "Union of Soviet Socialist Republics" or Soviet Union).ti,ab,in. 234884 49 Finland/ or finland.ti,ab,in. 170587 50 exp France/ or france.ti,ab,in. 914159 51 exp Germany/ or germany.ti,ab,in. 1248632 52 Greece/ or greece.ti,ab,in. 142751 53 Iceland/ or iceland.ti,ab,in. 13501 54 Ireland/ or (ireland or eire).ti,ab,in. 133615 55 exp Italy/ or italy.ti,ab,in. 926772 56 Luxembourg/ or luxembourg.ti,ab,in. 8654 57 Netherlands/ or (netherlands or holland).ti,ab,in. 579539 58 Poland/ or poland.ti,ab,in. 246287 59 Portugal/ or portugal.ti,ab,in. 125678 60 Slovakia/ or (slovakia or slovak republic).ti,ab,in. 26469 61 Slovenia/ or slovenia.ti,ab,in. 29275 62 Spain/ or (spain or balearic islands or canary islands).ti,ab,in. 602967 63 Switzerland/ or switzerland.ti,ab,in. 366721 64 exp United Kingdom/ or (great britain or GBR or united kingdom or UK or northern ireland or scotland or channel islands or isle of man or (wales not new south wales) or (england not new england)).ti,ab,in. 1879507 65 europe/ or balkan peninsula/ or europe, eastern/ or gibraltar/ or mediterranean region/ or mediterranean islands/ or vatican city/ 119760 66 (europe or balkans or mediterranean or vatican or gibraltar).ti,ab,in. 171139 67 Israel/ or israel.ti,ab,in. 265840 68 north america/ or north america.ti,ab,in. 53852 69 exp canada/ or canada.ti,ab,in. 948173 70 exp United States/ or (united states or USA).ti,ab,in. 6183456 71 australasia/ or australasia.ti,ab,in. 2940 72 exp australia/ or Australia.ti,ab,in. 740116 73 New Zealand/ or New Zealand.ti,ab,in. 157373 74 Singapore/ or Singapore.ti,ab,in. 118945 75 Taiwan/ or taiwan.ti,ab,in. 259963 76 non-endemic.ti,ab. 3597 77 or/16-76 [NON-ENDEMIC COUNTRIES] 15869794 78 8 and 15 and 77 [EOSINOPHILIA AND TRAVELLERS AND NON-ENDEMIC COUNTRIES] 328 79 exp animals/ not humans.sh. 4932172 80 78 not 79 318 81 limit 80 to english language 276 82 remove duplicates from 81 276 Ovid Embase Classic+Embase Database name: Embase Classic + Embase Database platform: Ovid Dates of database coverage: 1947 to 2021 December 17 Date searched: 20 December 2021 Searched by: JF Number of results: 736 EndNote import order: 2 Number of results once duplicates removed: 515 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract IN: author institution address KW: author keyword PT: publication type TI: title or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. 1 exp eosinophilia/ 47585 2 (eosinophili* or hypereosinophili*).ti,ab. 79870 3 or/1-2 94948 4 travel/ or travel related disease/ or emporiatrics/ 58476 5 exp military personnel/ or military deployment/ or military service/ or military medicine/ 35486 6 clergy/ 6023 7 exp migrant/ or undocumented immigrant/ 44088 8 (travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or ((army or navy or armed forces or air force) adj1 personnel) or expat* or missionar* or migrant? or immigrant? or emigrant? or refugee* or asylum or (import* adj2 (infect* or diseas*)) or (visit* adj2 (friend* or family or families or relativ* or relation*)) or vfr).ti,ab,kw. 288056 9 or/4-8 332702 10 europe/ or eastern europe/ or southern europe/ or western europe/ or europe.ti,ab,in. 272620 11 vatican city state/ or Gibraltar/ or (mediterranean or vatican or gibraltar).ti,ab,in. 57732 12 Andorra/ or Andorra.ti,ab,in. 452 13 Austria/ or Austria.ti,ab,in. 330095 14 Baltic States/ or balkan peninsula/ or ((Baltic or Balkan) adj1 (state? or countr* or region or peninsula)).ti,ab,in. 2412 15 exp Belgium/ or Belgium.ti,ab,in. 455568 16 benelux/ or Benelux.ti,ab,in. 509 17 Croatia/ or croatia.ti,ab,in. 63864 18 Czech Republic/ or Czechoslovalia/ or (Czech Republic or Czechia or Czechoslovakia).ti,ab,in. 213736 19 Cyprus/ or Cyprus.ti,ab,in. 15526 20 Denmark/ or Denmark.ti,ab,in. 399824 21 Estonia/ or Estonia.ti,ab,in. 20501 22 faroe islands/ or Faroe Islands.ti,ab,in. 1040 23 exp Finland/ or Finland.ti,ab,in. 249383 24 exp France/ or (France or French Republic).ti,ab,in. 1656769 25 exp Germany/ or Germany.ti,ab,in. 2401095 26 Greece/ or (Greece or Hellenic Republic).ti,ab,in. 221972 27 Greenland/ or Greenland.ti,ab,in. 7169 28 Hungary/ or Hungary.ti,ab,in. 171878 29 Iceland/ or Iceland.ti,ab,in. 19204 30 Ireland/ or (Ireland or Eire).ti,ab,in. 337758 31 exp Italy/ or (Italy or Italian Republic).ti,ab,in. 1542178 32 Latvia/ or Latvia.ti,ab,in. 10202 33 Liechtenstein/ or Liechtenstein.ti,ab,in. 1669 34 Lithuania/ or Lithuania.ti,ab,in. 22526 35 Luxembourg/ or Luxembourg.ti,ab,in. 13696 36 Malta/ or Malta.ti,ab,in. 9354 37 monaco/ or Monaco.ti,ab,in. 10731 38 Netherlands/ or (Netherlands or Holland).ti,ab,in. 919850 39 exp Norway/ or Norway.ti,ab,in. 249823 40 Poland/ or Poland.ti,ab,in. 423696 41 exp Portugal/ or (Portugal or Portuguese Republic).ti,ab,in. 197590 42 San Marino/ or San Marino.ti,ab,in. 588 43 Scandinavia/ or (((Scandinavian or Nordic) adj1 (countr* or state? or region)) or Scandinavia).ti,ab,in. 12254 44 Slovakia/ or (Slovakia or Slovak Republic).ti,ab,in. 46669 45 Slovenia/ or Slovenia.ti,ab,in. 45769 46 exp Spain/ or (Spain or Balearic Islands or Canary Islands).ti,ab,in. 1013660 47 Sweden/ or Sweden.ti,ab,in. 616383 48 Switzerland/ or (Switzerland or Swiss Confederation).ti,ab,in. 652139 49 exp United Kingdom/ or channel islands/ or "isle of man"/ or (United Kingdom or UK or Great Britain or GBR or Northern Ireland or Scotland or Channel Islands or Isle of Man or Wales or England).ti,ab,in. 3270732 50 Moldova/ or Moldova.ti,ab,in. 3915 51 exp Ukraine/ or Ukraine.ti,ab,in. 66892 52 Albania/ or Albania.ti,ab,in. 5190 53 Armenia/ or Armenia.ti,ab,in. 7882 54 exp Azerbaijan/ or Azerbaijan.ti,ab,in. 7042 55 Belarus/ or (Belarus or Byelarus or Byelorussia or Belorussia).ti,ab,in. 13955 56 exp "Bosnia and Herzegovina"/ or (Bosnia or Herzegovina).ti,ab,in. 10616 57 Bulgaria/ or Bulgaria.ti,ab,in. 59437 58 exp "Georgia (republic)"/ or Georgia.ti,ab,in. 146112 59 Kosovo/ or Kosovo.ti,ab,in. 2244 60 "Montenegro (republic)"/ or Montenegro.ti,ab,in. 7722 61 "republic of north macedonia"/ or North Macedonia.ti,ab,in. 5196 62 Romania/ or Romania.ti,ab,in. 96274 63 exp Russian Federation/ or USSR/ or (Russia or Russian Federation or USSR or Union of Soviet Socialist Republics or Soviet Union).ti,ab,in. 494296 64 exp Serbia/ or Serbia.ti,ab,in. 53754 65 "Turkey (republic)"/ or (Turkey.ti,ab,in. not "Turkey (bird)"/) or (Anatolia or Asia Minor).ti,ab,in. 463127 66 Israel/ or Israel.ti,ab,in. 402146 67 north america/ or North America.ti,ab,in. 71944 68 exp United States/ or (united states or USA).ti,ab,in. 11316406 69 exp Canada/ or Canada.ti,ab,in. 1450881 70 exp "Australia and New Zealand"/ or (Australia or New Zealand).ti,ab,in. 1262285 71 Singapore/ or Singapore.ti,ab,in. 166843 72 Taiwan/ or Taiwan.ti,ab,in. 337928 73 non-endemic.ti,ab. 4865 74 or/10-73 26380063 75 3 and 9 and 74 1520 76 case report/ or exp case study/ or editorial/ or editorial.pt. or (editorial* or (case adj1 (histor* or report* or study or studies))).ti,ab,kw. 3865172 77 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1131393 78 Animal experiment/ not (human experiment/ or human/) 2378548 79 or/76-78 6292855 80 75 not 79 835 81 limit 80 to english language 743 82 remove duplicates from 81 736 Ovid Global Health Database name: Global Health Database platform: Ovid Dates of database coverage: 1910 to 2021 week 50 Date searched: 20 December 2021 Searched by: JF Number of results: 269 EndNote import order: 4 Number of results once duplicates removed: 127 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract IN: author institution address PT: publication type TI: title or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. 1 exp eosinophilia/ 5481 2 (eosinophilia or hypereosinophili*).ti,ab. 8061 3 or/1-2 8436 4 editorial.pt. 3035 5 case reports/ or case studies/ 116268 6 (editorial* or (case adj1 (histor* or report* or study or studies))).ti,ab. 70149 7 or/4-6 149108 8 3 not 7 6913 9 travel/ or international travel/ 5745 10 travel associated diseases/ 587 11 travel medicine/ 2406 12 exp tourism/ 4704 13 exp military personnel/ 12996 14 military medicine/ 368 15 migrants/ or visitors/ 5099 16 immigrants/ or immigration/ 9394 17 refugees/ 4775 18 imported infections/ 8832 19 (travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or ((army or navy or armed forces or air force) adj1 personnel) or expat* or missionar* or migrant? or immigrant? or emigrant? or refugee* or asylum or (import* adj2 (infect* or diseas*)) or (visit* adj2 (friend* or family or families or relativ* or relation*)) or vfr).ti,ab. 88475 20 or/9-19 98223 21 Armenia/ or Armenia.ti,ab,in. 1325 22 "republic of georgia"/ or georgia.ti,ab,in. 27897 23 Yugoslavia/ or yugoslavia.ti,ab,in. 5469 24 Kosovo/ or Kosovo.ti,ab,in. 777 25 Moldova/ or Moldova.ti,ab,in. 990 26 Ukraine/ or Ukraine.ti,ab,in. 6331 27 Albania/ or Albania.ti,ab,in. 1554 28 Azerbaijan/ or Azerbaijan.ti,ab,in. 2042 29 Belarus/ or (belarus or byelarus or belorussia).ti,ab,in. 1585 30 bosnia-hercegovina/ or (bosnia or herzegovina or hercegovina).ti,ab,in. 2688 31 Bulgaria/ or Bulgaria.ti,ab,in. 9984 32 Hungary/ or hungary.ti,ab,in. 14416 33 "republic of north macedonia"/ or macedonia.ti,ab,in. 2272 34 montenegro/ or montenegro.ti,ab,in. 1632 35 Romania/ or romania.ti,ab,in. 18639 36 serbia/ or "serbia and montenegro"/ 4444 37 serbia/ or "serbia and montenegro"/ or serbia.ti,ab,in. 9580 38 turkey/ or (turkey.ti,ab,in. not (turkeys/ or animals/)) 48592 39 Andorra/ or Andorra.ti,ab,in. 42 40 Croatia/ or croatia.ti,ab,in. 9255 41 Cyprus/ or Cyprus.ti,ab,in. 2438 42 Liechtenstein/ or Liechtenstein.ti,ab,in. 107 43 Malta/ or Malta.ti,ab,in. 2100 44 Monaco/ or Monaco.ti,ab,in. 312 45 San Marino/ or San Marino.ti,ab,in. 71 46 Austria/ or Austria.ti,ab,in. 21142 47 Belgium/ or Belgium.ti,ab,in. 35400 48 Czech Republic/ or (czechoslovakia or czech republic).ti,ab,in. 21848 49 exp Denmark/ or (denmark or faeroe islands).ti,ab,in. 40083 50 Sweden/ or Sweden.ti,ab,in. 55613 51 exp Norway/ or norway.ti,ab,in. 26229 52 Scandinavia/ or scandinavia.ti,ab,in. 56286 53 exp baltic states/ or (baltic or estonia or latvia or lithuania).ti,ab,in. 8970 54 exp Russia/ or exp USSR/ or (Russia or Russian Federation or USSR or "Union of Soviet Socialist Republics" or Soviet Union).ti,ab,in. 51581 55 exp Finland/ or finland.ti,ab,in. 27033 56 exp France/ or france.ti,ab,in. 133036 57 exp Germany/ or Germany.ti,ab,in. 129386 58 exp Greece/ or greece.ti,ab,in. 23883 59 iceland/ or iceland.ti,ab,in. 2627 60 Irish Republic/ or (ireland or irish republic or eire).ti,ab,in. 20386 61 exp Italy/ or italy.ti,ab,in. 132372 62 Luxembourg/ or Benelux/ or (luxembourg or benelux).ti,ab,in. 41663 63 Netherlands/ or (netherlands or holland).ti,ab,in. 75250 64 Poland/ or poland.ti,ab,in. 54628 65 exp portugal/ or portugal.ti,ab,in. 20953 66 slovakia/ or (slovakia or slovak republic).ti,ab,in. 8156 67 slovenia/ or slovenia.ti,ab,in. 6833 68 exp spain/ or (spain or balearic islands or canary islands).ti,ab,in. 104755 69 Switzerland/ or (Switzerland or Swiss Confederation).ti,ab,in. 48693 70 exp UK/ or (great britain or GBR or united kingdom or UK or scotland or channel islands or isle of man or wales or england).ti,ab,in. 280614 71 europe/ or central europe/ or northern europe/ or southern europe/ or western europe/ or europe.ti,ab,in. 558098 72 balkans/ or (balkan or balkans).ti,ab,in. 46766 73 mediterranean region/ or mediterranean.ti,ab,in. 287082 74 Gibraltar/ or gibraltar.ti,ab,in. 110 75 vatican/ or vatican.ti,ab,in. 26 76 Israel/ or israel.ti,ab,in. 27068 77 North America/ or North America.ti,ab,in. 430154 78 exp Canada/ or canada.ti,ab,in. 122008 79 exp USA/ or (united states or usa).ti,ab,in. 859005 80 Australasia/ or Australasia.ti,ab,in. 87680 81 exp Australia/ or Australia.ti,ab,in. 125491 82 New Zealand/ or New Zealand.ti,ab,in. 30016 83 Singapore/ or singapore.ti,ab,in. 14234 84 Taiwan/ or Taiwan.ti,ab,in. 47914 85 non-endemic.ti,ab. 3228 86 or/21-85 2458408 87 8 and 20 and 86 397 88 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 533996 89 87 not 88 391 90 limit 89 to english language 270 91 remove duplicates from 90 269 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 20 December 2021 Searched by: JF Number of results: 84 EndNote import order: 5 Number of results once duplicates removed: 18 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract AF: Author address MH: thesaurus terms TI: title Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. S1 (MH "Eosinophilia+") 3,482 S2 (TI (eosinophili* or hypereosinophili*)) or (AB (eosinophili* or hypereosinophili*)) 6,342 S3 S1 OR S2 7,082 S4 (MH "Travel+") OR (MH "Vacations") 16,759 S5 (MH "Travel Health") 3,947 S6 (MH "Military Personnel+") 17,857 S7 (MH "Military Deployment+") 1,292 S8 (MH "Military Medicine") 4,980 S9 (MH "Transients and Migrants") OR (MH "Immigrants+") OR (MH "Refugees+") OR (MH "Emigration and Immigration") 33,750 S10 (MH "Communicable Diseases, Imported") 70 S11 (TI (travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or ((army or navy or armed forces or "air force") N1 personnel) or expat* or missionar* or migrant or immigrant or emigrant or refugee* or asylum or (import* N2 (infect* or diseas*)) or (visit* N2 (friend* or family or families or relativ* or relation*)) or vfr)) or (AB (travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or ((army or navy or armed forces or "air force") N1 personnel) or expat* or missionar* or migrant or immigrant or emigrant or refugee* or asylum or (import* N2 (infect* or diseas*)) or (visit* N2 (friend* or family or families or relativ* or relation*)) or vfr)) 87,845 S12 S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 119,442 S13 (MH "Armenia") or (TI Armenia) or (AB Armenia) or (AF Armenia) 654 S14 (MH "Georgia (Republic)") or (TI Georgia) OR (AB Georgia) or (AF Georgia) 42,613 S15 (MH "Yugoslavia") or (TI Yugoslavia) or (AB Yugoslavia) or (AF Yugoslavia) 783 S16 (TI Kosovo) or (AB Kosovo) or (AF Kosovo) 507 S17 (MH "Moldova") or (TI Moldova) or (AB Moldova) or (AF Moldova) 387 S18 (MH "Ukraine") or (TI Ukraine) or (AB Ukraine) or (AF Ukraine) 2,339 S19 (MH "Albania") or (TI Albania) or (AB Albania) or (AF Albania) 677 S20 (MH "Azerbaijan") or (TI Azerbaijan) or (AB Azerbaijan) or (AF Azerbaijan) 631 S21 (MH "Byelarus") or (TI (belarus or byelarus or belorussia)) or (AB (belarus or byelarus or belorussia)) or (AF (belarus or byelarus or belorussia)) 634 S22 (MH "Bosnia-Herzegovina") or (TI (bosnia or herzegovina or hercegovina)) or (AB (bosnia or herzegovina or hercegovina)) or (AF (bosnia or herzegovina or hercegovina)) 1,169 S23 (MH "Bulgaria") or (TI Bulgaria) or (AB Bulgaria) or (AF Bulgaria) 2,582 S24 (MH "Hungary") or (TI Hungary) or (AB Hungary) or (AF Hungary) 9,495 S25 (MH "Macedonia (Republic)") or (TI Macedonia) or (AB Macedonia) or (AF Macedonia) 885 S26 (TI Montenegro) or (AB Montenegro) or (AF Montenegro) 415 S27 (MH "Romania") or (TI Romania) or (AB Romania) or (AF Romania) 6,812 S28 (MH "Serbia") or (TI Serbia) or (AB Serbia) or (AF Serbia) 5,945 S29 (MH "Turkey") or (((TI Turkey) or (AB Turkey) or (AF Turkey)) not (MH Poultry)) 82,943 S30 (MH "Andorra") or (TI Andorra) or (AB Andorra) or (AF Andorra) 75 S31 (MH "Croatia") or (TI Croatia) or (AB Croatia) or (AF Croatia) 5,472 S32 (MH "Mediterranean Islands") 1,266 S33 (TI Cyprus) or (AB Cyprus) or (AF Cyprus) 3,366 S34 (MH "Liechtenstein") or (TI Liechtenstein) or (AB Liechtenstein) or (AF Liechtenstein) 175 S35 (TI Malta) or (AB Malta) or (AF Malta) 1,915 S36 (MH "Monaco") or (TI Monaco) or (AB Monaco) or (AF Monaco) 380 S37 (MH "San Marino") or (TI "San Marino") or (AB "San Marino") OR (AF "San Marino") 211 S38 (MH "Austria") or (TI Austria) or (AB Austria) or (AF Austria) 30,439 S39 (MH "Belgium") or (TI Belgium) or (AB Belgium) or (AF Belgium) 53,491 S40 (MH "Czech Republic") or (TI (czechoslovakia or "czech republic")) or (AB (czechoslovakia or "czech republic")) or (AF (czechoslovakia or "czech republic")) 11,941 S41 (MH "Denmark") or (TI (denmark or "faeroe islands")) or (AB (denmark or "faeroe islands")) or (AF (denmark or "faeroe islands")) 57,855 S42 (MH "Sweden") or (TI Sweden) or (AB Sweden) or (AF Sweden) 90,696 S43 (MH "Norway") or (TI Norway) or (AB Norway) or (AF Norway) 44,655 S44 (MH "Scandinavia") or (TI Scandinavia) or (AB Scandinavia) or (AF Scandinavia) 1,686 S45 (MH "Baltic States+") or (TI (Baltic or Estonia or Latvia or Lithuania)) or (AB (Baltic or Estonia or Latvia or Lithuania)) or (AF (Baltic or Estonia or Latvia or Lithuania)) 6,340 S46 (MH "Russia") OR (MH "USSR") or (TI (Russia or "Russian Federation" or USSR or "Union of Soviet Socialist Republics" or "Soviet Union")) or (AB (Russia or "Russian Federation" or USSR or "Union of Soviet Socialist Republics" or "Soviet Union")) or (AF (Russia or "Russian Federation" or USSR or "Union of Soviet Socialist Republics" or "Soviet Union")) 13,877 S47 (MH "Finland") or (TI Finland) or (AB Finland) or (AF Finland) 37,757 S48 (MH "France") or (TI France) or (AB France) or (AF France) 122,628 S49 (MH "Germany+") or (TI Germany) or (AB Germany) or (AF Germany) 176,489 S50 (MH "Greece") or (TI Greece) or (AB Greece) or (AF Greece) 32,800 S51 (MH "Iceland") or (TI Iceland) or (AB Iceland) or (AF Iceland) 3,646 S52 (MH "Ireland") or (TI (ireland or eire or "irish republic")) or (AB (ireland or eire or "irish republic")) or (AF (ireland or eire or "irish republic")) 52,391 S53 (MH "Italy") or (TI Italy) or (AB Italy) or (AF Italy) 162,914 S54 (MH "Luxembourg") or (TI Luxembourg) or (AB Luxembourg) or (AF Luxembourg) 1,772 S55 (MH "Netherlands") or (TI (Netherlands or Holland)) or (AB (Netherlands or Holland)) or (AF (Netherlands or Holland)) 141,658 S56 (MH "Poland") or (TI Poland) or (AB Poland) or (AF Poland) 31,196 S57 (MH "Portugal") or (TI Portugal) or (AB Portugal) or (AF Portugal) 24,630 S58 (MH "Slovakia") or (TI (Slovakia or "Slovak Republic")) or (AB (Slovakia or "Slovak Republic")) or (AF (Slovakia or "Slovak Republic")) 3,167 S59 (MH "Slovenia") or (TI Slovenia) or (AB Slovenia) or (AF Slovenia) 5,906 S60 (MH "Spain") or (TI (spain or "balearic islands" or "canary islands")) or (AB (spain or "balearic islands" or "canary islands")) or (AF (spain or "balearic islands" or "canary islands")) 101,151 S61 (MH "Switzerland") or (TI Switzerland) or (AB Switzerland) or (AF Switzerland) 68,066 S62 (MH "United Kingdom+") or (TI ("great britain" or GBR or "united kingdom" or UK or scotland or "channel islands" or "isle of man" or wales or england)) or (AB ("great britain" or GBR or "united kingdom" or UK or scotland or "channel islands" or "isle of man" or wales or england)) or (AF ("great britain" or GBR or "united kingdom" or UK or scotland or "channel islands" or "isle of man" or wales or england)) 761,855 S63 (MH "Europe") OR (MH "Europe, Eastern") or (TI Europe) or (AB Europe) or (AF Europe) 52,874 S64 (TI (Balkan or balkans)) or (AB (Balkan or balkans)) or (AF (Balkan or balkans)) 396 S65 (MH "Gibraltar") or (TI Gibraltar) or (AB Gibraltar) or (AE Gibraltar) 83 S66 (MH "Mediterranean Region") or (TI Mediterranean) or (AB Mediterranean) or (AF Mediterranean) 9,222 S67 (TI Vatican) or (AB Vatican) or (AF Vatican) 118 S68 (MH "Israel") or (TI Israel) or (AB Israel) or (AF Israel) 61,303 S69 (MH "North America") or (TI "North America" or (AB "North America" or (AF "North America") 10,999 S70 (MH "Canada+") or (TI Canada) or (AB Canada) or (AF Canada) 293,657 S71 (MH "United States+") or (TI ("United States" or USA)) or (AB ("United States" or USA)) or (AF ("United States" or USA)) 1,564,061 S72 (TI Australasia) or (AB Australasia) or (AF Australasia) 990 S73 (MH "Australia+") or (TI Australia) or (AB Australia) or (AF Australia) 297,154 S74 (MH "New Zealand") or (TI "New Zealand") or (AB "New Zealand") or (AF "New Zealand") 65,395 S75 (MH "Singapore") or (TI Singapore) or (AB Singapore) or (AF Singapore) 24,871 S76 (MH "Taiwan") or (TI Taiwan) or (AB Taiwan) or (AF Taiwan) 57,978 S77 (TI "non-endemic") or (AB "non-endemic") 423 S78 S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45 OR S46 OR S47 OR S48 OR S49 OR S50 OR S51 OR S52 OR S53 OR S54 OR S55 OR S56 OR S57 OR S58 OR S59 OR S60 OR S61 OR S62 OR S63 OR S64 OR S65 OR S66 OR S67 OR S68 OR S69 OR S70 OR S71 OR S72 OR S73 OR S74 OR S75 OR S76 OR S77 3,851,983 S79 S3 AND S12 AND S78 139 S80 S79 Limiters - Publication Type: Case Study, Editorial 54 S81 S79 not S80 85 S82 S81 Limiters - Language: English 84 Wiley Cochrane Central Register of Controlled Trials Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 12 of 12, December 2021 Date searched: 20 December 2021 Searched by: JF Number of results: 15 EndNote import order: 7 Number of results once duplicates removed: 11 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. # Search terms Results #1 MeSH descriptor: [Eosinophilia] explode all trees 421 #2 (eosinophili* or hypereosinophili*):ti,ab,kw 2477 #3 #1 or #2 2477 #4 MeSH descriptor: [Travel] explode all trees 322 #5 MeSH descriptor: [Travel Medicine] this term only 4 #6 MeSH descriptor: [Military Personnel] this term only 1019 #7 MeSH descriptor: [Military Medicine] this term only 169 #8 MeSH descriptor: [Military Deployment] this term only 2 #9 MeSH descriptor: [Emigrants and Immigrants] explode all trees 195 #10 MeSH descriptor: [Missionaries] this term only 0 #11 MeSH descriptor: [Transients and Migrants] this term only 73 #12 MeSH descriptor: [Communicable Diseases, Imported] this term only 1 #13 (travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or ((army or navy or "armed forces" or "air force") NEXT personnel) or expat* or missionar* or migrant* or immigrant* or emigrant* or refugee* or asylum or (import* NEAR/2 (infect* or diseas*)) or (visit* NEAR/2 (friend* or family or families or relativ* or relation*)) or vfr):ti,ab,kw 11560 #14 #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 11574 #15 #3 and #14 16 Clarivate Analytics Web of Science Core Collection Database name: Web of Science Core Collection which contains the following databases: Science Citation Index Expanded (Sci-Expanded) Social Sciences Citation Index (SSCI) Arts & Humanities Citation Index (AHCI) Conference Proceedings Citation Index-Science (SPCI-S) Conference Proceedings Citation Index-Social Science & Humanities (CPCI-SSH) Emerging Sources Citation Index (ESCI) All databases are searched simultaneously. Database platform: Clarivate Analytics Web of Science Dates of database coverage: Sci-Expanded 1970-present SSCI-1970-present AHCI-1975-present CPCI-S 1990-present CPCI-SSH 1990-present ESCI 2015-present Date searched: 20 December 2021 Searched by: JF Number of results: 273 EndNote import order: 6 Number of results once duplicates removed: 114 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract CU: country TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results #10 #9 and English (Languages) 273 #9 #7 not #8 and Editorial Materials or Letters (Exclude – Document Types) 341 #8 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 2,415,770 #7 #1 and #2 and #6 369 #6 #3 or #4 or #5 32,433,024 #5 CU=("Armenia" or "Georgia" or "Yugoslavia" or "Kosovo" or "Moldova" or "Ukraine" or "Albania" or "Azerbaijan" or "Belarus" or "Byelarus" or "Belorussia" or "Bosnia" or "Herzegovina" or "Hercegovina" or "Bulgaria" or "Hungary" or "Macedonia" or "Montenegro" or "Romania" or "Serbia" or ("Turkey" not "turkeys") or "Androrra" or "Croatia" or "Cyprus" or "Liechtenstein" or "Malta" or "Monaco" or "San Marino" or "Austria" or "Belgium" or "Czechoslovakia" or "Czech Republic" or "Denmark" or "Faroe Islands" or "Sweden" or "Norway" or "Scandinavia" or "Baltic" or "Estonia" or "Latvia" or "Lithuania" or "Russia" or "Russian Federation" or "USSR" or "Union of Soviet Socialist Republics" or "Soviet Union" or "Finland" or "France" or "Germany" or "Greece" or "Iceland" or "Ireland" or "Eire" or "Irish Republic" or "Italy" or "Luxembourg" or "Netherlands" or "Holland" or "Poland" or "Portugal" or "Slovakia" or "Slovak Republic" or "Slovenia" or "Spain" or "Balearic Islands" or "Canary Islands" or "Switzerland" or "Great Britain" or "GBR" or "United Kingdom" or "UK" or "Scotland" or "Wales" or "Channel Islands" or "Isle of Man" or "England" or "Europe" or "Balkan" or "Balkans" or "Mediterranean" or "Vatican" or "Gibraltar" or "Israel" or "North America" or "Canada" or "United States" or "Australasia" or "Australia" or "New Zealand" or "Singapore" or "Taiwan" ) 31,291,370 #4 AB=("Armenia" or "Georgia" or "Yugoslavia" or "Kosovo" or "Moldova" or "Ukraine" or "Albania" or "Azerbaijan" or "Belarus" or "Byelarus" or "Belorussia" or "Bosnia" or "Herzegovina" or "Hercegovina" or "Bulgaria" or "Hungary" or "Macedonia" or "Montenegro" or "Romania" or "Serbia" or ("Turkey" not "turkeys") or "Androrra" or "Croatia" or "Cyprus" or "Liechtenstein" or "Malta" or "Monaco" or "San Marino" or "Austria" or "Belgium" or "Czechoslovakia" or "Czech Republic" or "Denmark" or "Faroe Islands" or "Sweden" or "Norway" or "Scandinavia" or "Baltic" or "Estonia" or "Latvia" or "Lithuania" or "Russia" or "Russian Federation" or "USSR" or "Union of Soviet Socialist Republics" or "Soviet Union" or "Finland" or "France" or "Germany" or "Greece" or "Iceland" or "Ireland" or "Eire" or "Irish Republic" or "Italy" or "Luxembourg" or "Netherlands" or "Holland" or "Poland" or "Portugal" or "Slovakia" or "Slovak Republic" or "Slovenia" or "Spain" or "Balearic Islands" or "Canary Islands" or "Switzerland" or "Great Britain" or "GBR" or "United Kingdom" or "UK" or "Scotland" or "Wales" or "Channel Islands" or "Isle of Man" or "England" or "Europe" or "Balkan" or "Balkans" or "Mediterranean" or "Vatican" or "Gibraltar" or "Israel" or "North America" or "Canada" or "United States" or "Australasia" or "Australia" or "New Zealand" or "Singapore" or "Taiwan" or "non-endemic") 2,823,516 #3 TI=("Armenia" or "Georgia" or "Yugoslavia" or "Kosovo" or "Moldova" or "Ukraine" or "Albania" or "Azerbaijan" or "Belarus" or "Byelarus" or "Belorussia" or "Bosnia" or "Herzegovina" or "Hercegovina" or "Bulgaria" or "Hungary" or "Macedonia" or "Montenegro" or "Romania" or "Serbia" or ("Turkey" not "turkeys") or "Androrra" or "Croatia" or "Cyprus" or "Liechtenstein" or "Malta" or "Monaco" or "San Marino" or "Austria" or "Belgium" or "Czechoslovakia" or "Czech Republic" or "Denmark" or "Faroe Islands" or "Sweden" or "Norway" or "Scandinavia" or "Baltic" or "Estonia" or "Latvia" or "Lithuania" or "Russia" or "Russian Federation" or "USSR" or "Union of Soviet Socialist Republics" or "Soviet Union" or "Finland" or "France" or "Germany" or "Greece" or "Iceland" or "Ireland" or "Eire" or "Irish Republic" or "Italy" or "Luxembourg" or "Netherlands" or "Holland" or "Poland" or "Portugal" or "Slovakia" or "Slovak Republic" or "Slovenia" or "Spain" or "Balearic Islands" or "Canary Islands" or "Switzerland" or "Great Britain" or "GBR" or "United Kingdom" or "UK" or "Scotland" or "Wales" or "Channel Islands" or "Isle of Man" or "England" or "Europe" or "Balkan" or "Balkans" or "Mediterranean" or "Vatican" or "Gibraltar" or "Israel" or "North America" or "Canada" or "United States" or "Australasia" or "Australia" or "New Zealand" or "Singapore" or "Taiwan" or "non-endemic") 1,876,285 #2 TI=(travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or (("army" or "navy" or "armed forces" or "air force") near/1 "personnel") or expat* or missionar* or "migrant" or "immigrant" or "emigrant" or refugee* or "asylum" or (import* near/2 (infect* or diseas*)) or (visit* near/2 (friend* or "family" or "families" or relativ* or relation*)) or "vfr") or AB=(travel* or emporiatric* or touris* or militar* or soldier* or troop* or sailor* or (("army" or "navy" or "armed forces" or "air force") near/1 "personnel") or expat* or missionar* or "migrant" or "immigrant" or "emigrant" or refugee* or "asylum" or (import* near/2 (infect* or diseas*)) or (visit* near/2 (friend* or "family" or "families" or relativ* or relation*)) or "vfr") 674,791 #1 TI=(eosinophili* or hypereosinophili*) or AB=(eosinophili* or hypereosinophili*) 45,957 WHO Global Index Medicus: Western Pacific Region Index Medicus Database name: Western Pacific Region Index Medicus Database platform: World Health Organization Global Index Medicus Dates of database coverage: Complete database to search date Date searched: 20 December 2021 Searched by: JF Number of results: 21 EndNote import order: 8 Number of results once duplicates removed: 18 Search strategy notes: N/A (eosinophili* OR hypereosinophili*) AND (travel* OR emporiatric* OR touris* OR militar* OR soldier* OR troop* OR sailor* OR expat* OR missionar* OR migrant* OR immigrant* OR emigrant* OR refugee* OR asylum OR "imported disease" OR "imported infection" OR "imported diseases" OR "imported infections" OR (visit* AND (friend* OR family OR families OR relativ* OR relation*)) OR vfr) AND db:("WPRIM") AND NOT ( type_of_study:("case_reports")) AND ( la:("en")) WHO International Clinical Trials Registry Platform Database name: International Clinical Trials Registry Platform Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 20 December 2021 Searched by: JF Number of results: 219 EndNote import order: 9 Number of results once duplicates removed: 134 Search strategy notes: N/A Condition: (eosinophilic OR eosinophilia OR hypereosinophilia OR hypereosinophilic) Countries of recruitment: Albania, Andorra, Armenia, Australia, Austria, Azerbaijan, Belarus, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Georgia, Germany, Greece, Hungary, Iceland, Ireland, Israel, Italy, Kazakhstan, Latvia, Lithuania, Luxembourg, Malta, Monaco, Montenegro, Morocco, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Serbia, Singapore, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, United Kingdom, United States of America, Taiwan ClinicalTrials.gov Database name: ClinicalTrials.gov Database platform: Clinicaltrials.gov Dates of database coverage: Complete database to search date Date searched: 20 December 2021 Searched by: JF Number of results: 12 EndNote import order: 10 Number of results once duplicates removed: 10 Search strategy notes: N/A Condition: (eosinophilic OR eosinophilia OR hypereosinophilia OR hypereosinophilic) Other terms: (travel OR TRAVELLER OR EMPORIATRIC OR TOURIST OR TOURISM OR MILITARY OR SOLDIER OR SOLDIERS OR TROOPS OR SAILOR OR SAILORS OR ARMED FORCES OR EXPAT OR MISSIONARY OR MISSIONARIES OR MIGRANT OR MIGRANTS OR IMMIGRANT OR IMMIGRANTS OR EMIGRANT OR EMIGRANTS OR REFUGEE OR REFUGEES OR ASYLUM OR "IMPORTED INFECTION" OR "IMPORTED INFECTIONS" OR "IMPORTED DISEASE" OR "IMPORTED DISEASES" OR "VISIT FAMILY" OR "VISIT FRIENDS" OR "VISIT FAMILIES" OR "VISIT RELATIVES" OR "VISIT RELATIONS" OR VFR) Search 2: diagnosis of relevant pathogens For all searches the list of pathogens and resulting clinical conditions was agreed with the project team. The diagnosis filter was derived from the filter published by SIGN. [2] OvidSP Medline ALL Database name: Medline ALL Database platform: OvidSP Dates of database coverage: 1946 to December 20, 2021 Date searched: 21 December 2021 Searched by: JF Number of results: 5696 EndNote import order: 1 (Medline) and 3 (Medline In Process) Number of results once duplicates removed: 5354 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type SH: subject heading word TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp Schistosomiasis/ 24379 2 exp Schistosoma/ 18038 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 29661 4 exp Ancylostomatoidea/ 2644 5 exp Hookworm Infections/ 4307 6 exp Ascaris/ 5465 7 Ascariasis/ 5728 8 exp Strongyloides/ 2681 9 Strongyloidiasis/ 3875 10 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 19212 11 exp Larva Migrans/ 1601 12 exp Toxocara/ 2319 13 Toxocariasis/ 1997 14 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 4918 15 Wuchereria bancrofti/ 2360 16 Brugia/ or Brugia malayi/ 2151 17 filariasis/ or elephantiasis, filarial/ 8466 18 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 9694 19 exp echinococcosis/ 20122 20 exp Echinococcus/ 6119 21 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 20568 22 Paragonimiasis/ 1157 23 exp Paragonimus/ 935 24 (paragonimiasis or paragonimus or p westermani).ti,ab. 1815 25 coccidioidomycosis/ or paracoccidioidomycosis/ 5007 26 blastomyces/ or coccidioides/ or paracoccidioides/ 3998 27 Blastomycosis/ 2671 28 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 8400 29 exp Taenia/ 4296 30 cestode infections/ or exp taeniasis/ 11487 31 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 14412 32 hymenolepis/ or hymenolepis nana/ 1086 33 Hymenolepiasis/ 1106 34 (hymenolepi* or h nana).ti,ab. 2847 35 exp enoplida infections/ 7632 36 trichuroidea/ or Trichuris/ or exp trichinella/ 5485 37 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 4180 38 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 6310 39 Enterobius/ 955 40 Enterobiasis/ 778 41 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 2054 42 Anisakiasis/ 760 43 Anisakis/ 889 44 Ascaridoidea/ 825 45 Ascaridida Infections/ 549 46 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 1659 47 Angiostrongylus/ 670 48 Strongylida Infections/ 2557 49 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 1900 50 exp Fasciola/ 4415 51 Fascioliasis/ 4039 52 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 6151 53 exp Opisthorchidae/ 1938 54 clonorchiasis/ or opisthorchiasis/ 2536 55 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 5217 56 Gnathostomiasis/ 126 57 Gnathostoma/ 446 58 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 622 59 exp Onchocerca/ 2345 60 Onchocerciasis/ 3879 61 (onchocercias* or onchocerca or o volvulus).ti,ab. 5169 62 Loiasis/ 620 63 Loa/ 529 64 (loias* or loa loa).ti,ab. 902 65 Trichinellosis/ 4998 66 exp Trichinella/ 3773 67 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 5083 68 (swimmer* itch or cercarial dermatitis).ti,ab. 268 69 Sarcocystis/ 1630 70 Sarcocystosis/ 1575 71 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 240 72 Sparganosis/ 493 73 Sparganum/ 252 74 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 982 75 Histoplasmosis/ or Histoplasma/ or (histoplasm* or h capsulatum).ti,ab. 9142 76 Talaromyces/ or Penicillium/ or (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 16303 77 or/1-76 182357 78 gold standard.ti,ab. 76542 79 exp "Sensitivity and Specificity"/ 626062 80 (sensitivity or specificity).tw. 1133052 81 ((pre-test or pretest) adj probability).tw. 2546 82 post-test probability.tw. 664 83 predictive value*.tw. 121312 84 likelihood ratio*.tw. 17491 85 or/78-84 1651561 86 77 and 85 8880 87 exp animals/ not humans.sh. 4932653 88 (comment or editorial or letter or news).pt. 2217165 89 87 or 88 7067818 90 86 not 89 6303 91 limit 90 to english language 5703 92 remove duplicates from 91 5696 OvidSP Embase Classic+Embase Database name: Embase Classic+Embase Database platform: OvidSP Dates of database coverage: 1947 to 2021 December 20 Date searched: 21 December 2021 Searched by: JF Number of results: 9089 EndNote import order: 2 Number of results once duplicates removed: 4732 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp schistosomiasis/ 28590 2 schistosoma/ or schistosoma haematobium/ or schistosoma japonicum/ or schistosoma mansoni/ 24637 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 34972 4 hookworm/ or exp ancylostoma/ or exp necator/ 6685 5 exp hookworm infection/ 5277 6 exp Ascaris/ or Ascaris lumbricoides/ 10473 7 ascariasis/ 6825 8 strongyloides/ or strongyloides stercoralis/ 5150 9 exp strongyloidiasis/ 5286 10 Loeffler pneumonia/ 5209 11 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 23989 12 exp larva migrans/ 2350 13 exp Toxocara/ 4182 14 toxocariasis/ 2849 15 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 5977 16 Wuchereria bancrofti/ 3392 17 brugia/ or brugia malayi/ or brugia timori/ 2714 18 filariasis/ 10070 19 Brugian filariasis/ 206 20 Bancroftian filariasis/ 219 21 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 11765 22 exp echinococcosis/ 24945 23 exp Echinococcus/ 10208 24 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 25373 25 paragonimiasis/ 1600 26 paragonimus/ or paragonimus westermani/ 1445 27 (paragonimiasis or paragonimus or p westermani).ti,ab. 2206 28 coccidioidomycosis/ 5449 29 South American blastomycosis/ 2538 30 exp Blastomyces/ 1155 31 exp Coccidioides/ 2838 32 paracoccidioides/ or paracoccidioides brasiliensis/ 2441 33 blastomycosis/ 4064 34 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 10812 35 taenia/ or taenia saginata/ or taenia solium/ 5858 36 cestodiasis/ or exp taeniasis/ 13021 37 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 16563 38 hymenolepis/ or hymenolepis nana/ 2056 39 hymenolepiasis/ 305 40 (hymenolepi* or h nana).ti,ab. 3329 41 trichuris/ or trichuris trichiura/ 4649 42 enoplid infection/ or trichinosis/ or trichuriasis/ 7598 43 trichinella/ or trichinella spiralis/ 5223 44 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 5260 45 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 7189 46 exp Enterobius/ 2657 47 enterobiasis/ 2385 48 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 2719 49 ascarid infection/ or anisakiasis/ 1197 50 anisakis/ 1471 51 Ascaridoidea/ 913 52 pseudoterranova decipiens/ 45 53 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 2179 54 angiostrongylus/ or angiostrongylus costaricensis/ 883 55 strongyle infection/ 680 56 angiostrongyliasis/ 629 57 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 2178 58 exp Fasciola/ 6624 59 fascioliasis/ 4732 60 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 7031 61 exp opisthorchiidae/ 2964 62 clonorchiasis/ 1172 63 opisthorchiasis/ 1817 64 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 5899 65 gnathostomiasis/ 329 66 exp gnathostoma/ 221 67 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 713 68 onchocerca/ or onchocerca volvulus/ 3197 69 exp onchocerciasis/ 6092 70 (onchocercias* or onchocerca or o volvulus).ti,ab. 5992 71 loiasis/ 457 72 exp Loa/ 1138 73 (loias* or loa loa).ti,ab. 1219 74 trichinosis/ 5003 75 trichinella/ or trichinella spiralis/ 5223 76 cercarial dermatitis/ 73 77 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 5925 78 (swimmer* itch or cercarial dermatitis).ti,ab. 344 79 exp Sarcocystis/ 1964 80 sarcocystosis/ 415 81 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 271 82 sparganosis/ 396 83 sparganum/ 249 84 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1089 85 exp histoplasmosis/ 10797 86 exp Histoplasma/ 5535 87 (histoplasm* or h capsulatum).ti,ab. 10975 88 talaromyces/ or talaromyces marneffei/ 1030 89 Penicillium/ 12384 90 penicilliosis/ 337 91 (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 17507 92 or/1-91 233276 93 gold standard/ 61513 94 gold standard.ti,ab. 124937 95 exp "SENSITIVITY AND SPECIFICITY"/ 415987 96 sensitivity.tw. 1176437 97 specificity.tw. 668306 98 ((pre-test or pretest) adj probability).tw. 4498 99 post-test probability.tw. 944 100 predictive value$.tw. 181722 101 likelihood ratio$.tw. 23819 102 *Diagnostic Accuracy/ 15413 103 or/93-102 1840157 104 92 and 103 11109 105 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1131801 106 Animal experiment/ not (human experiment/ or human/) 2379156 107 (editorial or letter).pt. 1912316 108 or/105-107 4341722 109 104 not 108 10047 110 limit 109 to english language 9089 OvidSP Global Health Database name: Global Health Database platform: OvidSP Dates of database coverage: 1910 to 2021 Week 50 Date searched: 21 December 2021 Searched by: JF Number of results: 5340 EndNote import order: 4 Number of results once duplicates removed: 1468 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp schistosomiasis/ 47979 2 schistosoma/ or schistosoma haematobium/ or schistosoma japonicum/ or schistosoma mansoni/ 51569 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 48480 4 hookworms/ 10934 5 ascaris/ or ascaris lumbricoides/ 17420 6 ascariasis/ 6669 7 strongyloides/ or strongyloides stercoralis/ 8523 8 strongyloidiasis/ 6089 9 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 34335 10 larva migrans/ 1673 11 toxocara/ or toxocara canis/ or toxocara cati/ 6694 12 toxocariasis/ 2691 13 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 7320 14 exp wuchereria bancrofti/ 7785 15 brugia/ or brugia malayi/ or brugia timori/ 5364 16 filariasis/ or bancroftian filariasis/ or brugian filariasis/ 21430 17 elephantiasis/ 2041 18 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 16691 19 exp echinococcosis/ 14560 20 echinococcus/ or echinococcus granulosus/ or echinococcus multilocularis/ 20269 21 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 18793 22 paragonimus/ or paragonimiasis/ or paragonimus westermani/ 4122 23 (paragonimiasis or paragonimus or p westermani).ti,ab. 4068 24 coccidioidomycosis/ 3144 25 paracoccidioidomycosis/ 1921 26 exp blastomyces/ 3846 27 exp coccidioides/ 4610 28 exp paracoccidioides/ 3464 29 blastomycosis/ 2119 30 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 10294 31 taenia/ or taenia saginata/ or taenia solium/ 16494 32 cestode infections/ or taeniasis/ 47612 33 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 18466 34 "hymenolepis (cestoda)"/ or hymenolepis nana/ 6758 35 (hymenolepi* or h nana).ti,ab. 6957 36 trichuris/ or trichuridae/ or trichuriasis/ 11666 37 trichinella/ or trichinella spiralis/ 12428 38 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 10474 39 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 11982 40 enterobius/ or enterobius vermicularis/ 5723 41 enterobiasis/ 2246 42 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 5716 43 anisakiasis/ 1107 44 exp anisakis/ 1826 45 ascaridiosis/ 567 46 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 1838 47 angiostrongylus/ or angiostrongylus costaricensis/ 2503 48 angiostrongyliasis/ 903 49 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 2516 50 exp fasciola/ 8521 51 fascioliasis/ 6350 52 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 8205 53 opisthorchiidae/ or exp clonorchis/ or exp opisthorchis/ 6402 54 clonorchiasis/ 1829 55 opisthorchiasis/ 1831 56 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 8088 57 gnathostoma/ or gnathostoma spinigerum/ or gnathostomiasis/ 914 58 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 909 59 onchocerca/ or onchocerca volvulus/ 9448 60 onchocerciasis/ 7260 61 (onchocercias* or onchocerca or o volvulus).ti,ab. 9152 62 exp loa/ 2065 63 (loias* or loa loa).ti,ab. 1724 64 trichinosis/ 7853 65 trichinella/ or trichinella spiralis/ 12428 66 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 10669 67 cercarial dermatitis/ 574 68 (swimmer* itch or cercarial dermatitis).ti,ab. 455 69 exp sarcocystis/ 1500 70 sarcocystosis/ 515 71 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 248 72 sparganosis/ 591 73 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1247 74 exp histoplasmosis/ 5301 75 histoplasma/ or histoplasma capsulatum/ 8434 76 (histoplasm* or h capsulatum).ti,ab. 9119 77 talaromyces/ or talaromyces marneffei/ 1071 78 (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 11853 79 or/1-78 222425 80 gold standard.ti,ab. 10511 81 sensitivity.tw. 150152 82 specificity.tw. 74904 83 ((pre-test or pretest) adj probability).tw. 219 84 post-test probability.tw. 106 85 predictive value$.tw. 18602 86 likelihood ratio$.tw. 2712 87 or/80-86 191624 88 79 and 87 8114 89 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 533996 90 editorial.pt. 3035 91 89 or 90 536964 92 88 not 91 7037 93 limit 92 to english language 5502 94 remove duplicates from 93 5340 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: 178 EndNote import order: 5 Number of results once duplicates removed: 31 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract MH: thesaurus terms TI: title TW: textword Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. # Query Results S1 (MH "Schistosomiasis") 1,178 S2 (TI (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) or (AB (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) 1,320 S3 (MH "Hookworm Infections") OR (MH "Strongylida Infections") 334 S4 (TI (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) or (AB (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) 1,229 S5 (MH "Larva Migrans") 110 S6 (MH "Toxocariasis") OR (MH "Ascariasis") OR (MH "Ascaridida Infections") 484 S7 (TI ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) or (AB ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) 331 S8 (MH "Elephantiasis, Filarial") OR (MH "Filariasis") 606 S9 (TI ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) or (AB ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) 636 S10 (MH "Echinococcosis+") 1,468 S11 (TI (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) or (AB (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) 1,643 S12 (MH "Paragonimiasis") 47 S13 (TI (paragonimiasis or paragonimus or "p westermani" )) or (AB (paragonimiasis or paragonimus or "p westermani" )) 72 S14 (MH "Coccidioidomycosis") 448 S15 (MH "Blastomycosis") 182 S16 (TI (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) or (AB (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) 801 S17 (MH "Taeniasis") 92 S18 (TI (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) or (AB (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) 913 S19 (MH "Cestode Infections") 71 S20 (TI (hymenolepi* or "h nana")) or (AB (hymenolepi* or "h nana")) 70 S21 (MH "Enoplida Infections+") 184 S22 (TI (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) or (AB (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) 221 S23 (TI (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) or (AB (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) 123 S24 (MH "Enterobiasis") 127 S25 (TI (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) or (AB (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) 181 S26 (MH "Ascaridida Infections") OR (MH "Ascariasis") 351 S27 (TI (anisakias* or anisakis or "pseudoterranova decipiens")) or (AB (anisakias* or anisakis or "pseudoterranova decipiens")) 90 S28 (MH "Strongylida Infections") 123 S29 (TI (angiostrongyl* or "a costaricensis" or "rat lung worm")) or (AB (angiostrongyl* or "a costaricensis" or "rat lung worm")) 78 S30 (MH "Fascioliasis") 124 S31 (TI (fasciolias* or fasciola or "f hepatica" or "f giganta")) or (AB (fasciolias* or fasciola or "f hepatica" or "f giganta")) 138 S32 (MH "Clonorchiasis") OR (MH "Opisthorchiasis") 51 S33 (TI (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) or (AB (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) 144 S34 (TI (gnathostomias* or gnathostoma or "g spinigerum")) or (AB (gnathostomias* or gnathostoma or "g spinigerum")) 41 S35 (MH "Onchocerciasis+") 244 S36 (TI (onchocercias* or onchocerca or "o volvulus")) or (AB (onchocercias* or onchocerca or "o volvulus")) 323 S37 (TI (loias* or "loa loa")) or (AB (loias* or "loa loa")) 80 S38 (TI (trichinella or trichinellias* or trichinellos* or "t spiralis")) or (AB (trichinella or trichinellias* or trichinellos* or "t spiralis")) 92 S39 (TI ("swimmer* itch" or "cercarial dermatitis")) or (AB ("swimmer* itch" or "cercarial dermatitis")) 22 S40 (TI (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) or (AB (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) 16 S41 (MH "Sparganosis") 40 S42 (TI (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) or (AB (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) 56 S43 (MH "Histoplasmosis") 682 S44 (TI (histoplasm* or "h capsulatum")) or (AB (histoplasm* or "h capsulatum")) 756 S45 (TI (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) or (AB (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) 527 S46 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45 10,174 S47 (TI ("gold standard")) or (AB ("gold standard")) 18,366 S48 (MH "Sensitivity and Specificity") 88,798 S49 (TW (sensitivity or specificity or (("pre-test" or pretest) N1 probability) or "post-test probability" or "predictive value*" or "likelihood ratio*")) 1 S50 S47 OR S48 OR S49 104,325 S51 S46 AND S50 199 S52 (MH "Animals+") 100,150 S53 (MH "Animal Studies") 143,223 S54 (TI "animal model*") 3,298 S55 S52 OR S53 OR S54 234,609 S56 (MH human) 2,488,275 S57 S55 not S56 202,341 S58 S51 not S57 183 S59 S58 Limiters - Language: English 178 EBSCOhost Africa-Wide Information Database name: Africa-Wide Information Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: 3826 EndNote import order: 6 Number of results once duplicates removed: 919 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TX: textword * is used for truncation of words. Nn finds words within n words of each other, in any order. # Query Results S1 (TI (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) or (AB (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) 23,392 S2 (TI (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) or (AB (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) 6,732 S3 (TI ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) or (AB ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) 1,519 S4 (TI ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) or (AB ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) 11,968 S5 (TI (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) or (AB (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) 3,570 S6 (TI (paragonimiasis or paragonimus or "p westermani" )) or (AB (paragonimiasis or paragonimus or "p westermani" )) 513 S7 (TI (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) or (AB (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) 662 S8 (TI (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) or (AB (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) 7,308 S9 (TI (hymenolepi* or "h nana")) or (AB (hymenolepi* or "h nana")) 1,658 S10 (TI (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) or (AB (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) 2,493 S11 (TI (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) or (AB (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) 1,222 S12 (TI (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) or (AB (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) 583 S13 (TI (anisakias* or anisakis or "pseudoterranova decipiens")) or (AB (anisakias* or anisakis or "pseudoterranova decipiens")) 336 S14 (TI (angiostrongyl* or "a costaricensis" or "rat lung worm")) or (AB (angiostrongyl* or "a costaricensis" or "rat lung worm")) 364 S15 (TI (fasciolias* or fasciola or "f hepatica" or "f giganta")) or (AB (fasciolias* or fasciola or "f hepatica" or "f giganta")) 1,909 S16 (TI (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) or (AB (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) 1,126 S17 (TI (gnathostomias* or gnathostoma or "g spinigerum")) or (AB (gnathostomias* or gnathostoma or "g spinigerum")) 135 S18 (TI (onchocercias* or onchocerca or "o volvulus")) or (AB (onchocercias* or onchocerca or "o volvulus")) 5,932 S19 (TI (loias* or "loa loa")) or (AB (loias* or "loa loa")) 919 S20 (TI (trichinella or trichinellias* or trichinellos* or "t spiralis")) or (AB (trichinella or trichinellias* or trichinellos* or "t spiralis")) 1,106 S21 (TI ("swimmer* itch" or "cercarial dermatitis")) or (AB ("swimmer* itch" or "cercarial dermatitis")) 100 S22 (TI (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) or (AB (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) 130 S23 (TI (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) or (AB (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) 371 S24 (TI (histoplasm* or "h capsulatum")) or (AB (histoplasm* or "h capsulatum")) 1,062 S25 (TI (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) or (AB (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) 1,522 S26 S1 or S2 or S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 63,223 S27 (TI ("gold standard")) or (AB ("gold standard")) 3,996 S28 (TX (sensitivity or specificity or (("pre-test" or pretest) N1 probability) or "post-test probability" or "predictive value*" or "likelihood ratio*")) 69,697 S29 S27 OR S28 71,745 S30 S26 AND S29 4,514 S31 (TI (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*)) 85,119 S32 (TX (man or human)) 654,678 S33 S31 not S32 72,284 S34 S30 not S33 4,132 S35 S34 Limiters - Language: English 3,826 Clarivate Analytics Web of Science, Science Citation Index Database name: Science Citation Index-Expanded Database platform: Clarivate Analytics Web of Science Dates of database coverage: 1970-present Date searched: 21 December 2021 Searched by: JF Number of results: 5563 EndNote import order: 7 Number of results once duplicates removed: 1149 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 32 #30 NOT #31 and Notes or Editorial Materials or Letters (Exclude – Document Types) and English (Languages) 5,563 31 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 2,337,839 30 #3 AND #29 6,196 29 #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 125,324 28 TI= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") or AB= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") 23,358 27 TI=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") or AB=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") 14,654 26 TI=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") or AB=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") 3,985 25 TI=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") or AB=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") 7,010 24 TI=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") or AB=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") 12,965 23 TI=("paragonimiasis" or "paragonimus" or "p westermani") or AB=("paragonimiasis" or "paragonimus" or "p westermani") 998 22 TI=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") or AB=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") 6,631 21 TI=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") or AB=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") 12,540 20 TI=("hymenolepi*" or "h nana") or AB=("hymenolepi*" or "h nana") 2,220 19 TI=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") or AB=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") 3,384 18 TI=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") or AB=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") 4,429 17 TI=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") or AB=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") 1,139 16 TI=("anisakias*" or "anisakis" or "pseudoterranova decipiens") or AB=("anisakias*" or "anisakis" or "pseudoterranova decipiens") 1,863 15 TI=("angiostrongyl*" or "a costaricensis" or "rat lung worm") or AB=("angiostrongyl*" or "a costaricensis" or "rat lung worm") 1,587 14 TI=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") or AB=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") 5,294 13 TI=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") or AB=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") 3,641 12 TI=("gnathostomias*" or "gnathostoma" or "g spinigerum") or AB=("gnathostomias*" or "gnathostoma" or "g spinigerum") 419 11 TI=("onchocercias*" or "onchocerca" or "o volvulus") or AB=("onchocercias*" or "onchocerca" or "o volvulus") 4,574 10 TI=("loias*" or "loa loa") or AB=("loias*" or "loa loa") 723 9 TI=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") or AB=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") 4,026 8 TI=("swimmer* itch" or "cercarial dermatitis") or AB=("swimmer* itch" or "cercarial dermatitis") 192 7 TI=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") or AB=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") 162 6 TI=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") or AB=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") 733 5 TI=("histoplasm*" or "h capsulatum") or AB=("histoplasm*" or "h capsulatum") 5,430 4 TI=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") or AB=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") 21,043 3 #1 OR #2 1,671,047 2 TI="gold standard" or AB="gold standard" 62,689 1 TS= ("sensitivity" or "specificity" or (("pre-test" or "pretest") NEAR/1 "probability") or "post-test probability" or "predictive value*" or "likelihood ratio*") 1,626,006 Clarivate Analytics Web of Science SciELO Database name: SciELO Database platform: Clarivate Analytics Web of Science Dates of database coverage: 2002-present Date searched: 21 December 2021 Searched by: JF Number of results: 127 EndNote import order: 8 Number of results once duplicates removed: 5 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 32 #30 NOT #31 and English (Languages) 127 31 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 19,287 30 #3 AND #29 236 29 #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 OR #27 OR #28 4,504 28 TI= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") or AB= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") 859 27 TI=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") or AB=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") 736 26 TI=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") or AB=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") 334 25 TI=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") or AB=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") 103 24 TI=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") or AB=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") 294 23 TI=("paragonimiasis" or "paragonimus" or "p westermani") or AB=("paragonimiasis" or "paragonimus" or "p westermani") 21 22 TI=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") or AB=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") 395 21 TI=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") or AB=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") 481 20 TI=("hymenolepi*" or "h nana") or AB=("hymenolepi*" or "h nana") 100 19 TI=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") or AB=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") 256 18 TI=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") or AB=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") 62 17 TI=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") or AB=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") 101 16 TI=("anisakias*" or "anisakis" or "pseudoterranova decipiens") or AB=("anisakias*" or "anisakis" or "pseudoterranova decipiens") 79 15 TI=("angiostrongyl*" or "a costaricensis" or "rat lung worm") or AB=("angiostrongyl*" or "a costaricensis" or "rat lung worm") 109 14 TI=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") or AB=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") 251 13 TI=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") or AB=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") 24 12 TI=("gnathostomias*" or "gnathostoma" or "g spinigerum") or AB=("gnathostomias*" or "gnathostoma" or "g spinigerum") 22 11 TI=("onchocercias*" or "onchocerca" or "o volvulus") or AB=("onchocercias*" or "onchocerca" or "o volvulus") 43 10 TI=("loias*" or "loa loa") or AB=("loias*" or "loa loa") 8 9 TI=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") or AB=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") 54 8 TI=("swimmer* itch" or "cercarial dermatitis") or AB=("swimmer* itch" or "cercarial dermatitis") 1 7 TI=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") or AB=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") 3 6 TI=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") or AB=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") 24 5 TI=("histoplasm*" or "h capsulatum") or AB=("histoplasm*" or "h capsulatum") 280 4 TI=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") or AB=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") 654 3 #1 OR #2 16,586 2 TI="gold standard" or AB="gold standard" 2,039 1 TS= ("sensitivity" or "specificity" or (("pre-test" or "pretest") NEAR/1 "probability") or "post-test probability" or "predictive value*" or "likelihood ratio*") 15,248 Wiley Cochrane Central Register of Controlled Trials Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 12 of 12, December 2021 Date searched: 21 December 2021 Searched by: JF Number of results: 135 EndNote import order: 9 Number of results once duplicates removed: 33 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. # Search terms Results #1 MeSH descriptor: [Schistosomiasis] explode all trees 333 #2 MeSH descriptor: [Schistosoma] explode all trees 153 #3 (schistosomiasis or schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium"):ti,ab,kw 728 #4 MeSH descriptor: [Ancylostomatoidea] explode all trees 49 #5 MeSH descriptor: [Hookworm Infections] explode all trees 159 #6 MeSH descriptor: [Ascaris] explode all trees 83 #7 MeSH descriptor: [Ascariasis] this term only 152 #8 MeSH descriptor: [Strongyloides] explode all trees 19 #9 MeSH descriptor: [Strongyloidiasis] this term only 41 #10 (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis"):ti,ab,kw 738 #11 MeSH descriptor: [Larva Migrans] explode all trees 4 #12 MeSH descriptor: [Toxocara] explode all trees 1 #13 MeSH descriptor: [Toxocariasis] this term only 4 #14 ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*):ti,ab,kw 32 #15 MeSH descriptor: [Wuchereria bancrofti] this term only 102 #16 MeSH descriptor: [Brugia] this term only 6 #17 MeSH descriptor: [Brugia malayi] this term only 11 #18 MeSH descriptor: [Filariasis] this term only 90 #19 MeSH descriptor: [Elephantiasis, Filarial] this term only 134 #20 ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis):ti,ab,kw 406 #21 MeSH descriptor: [Echinococcosis] explode all trees 57 #22 MeSH descriptor: [Echinococcus] explode all trees 11 #23 (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis):ti,ab,kw 133 #24 MeSH descriptor: [Paragonimiasis] this term only 4 #25 MeSH descriptor: [Paragonimus] explode all trees 1 #26 (paragonimiasis or paragonimus or "p westermani"):ti,ab,kw 6 #27 MeSH descriptor: [Coccidioidomycosis] this term only 17 #28 MeSH descriptor: [Paracoccidioidomycosis] this term only 5 #29 MeSH descriptor: [Blastomyces] this term only 0 #30 MeSH descriptor: [Coccidioides] this term only 4 #31 MeSH descriptor: [Paracoccidioides] this term only 0 #32 MeSH descriptor: [Blastomycosis] this term only 5 #33 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or (paracoccidioidal NEXT granuloma*) or blastomycosis or blastomyces):ti,ab,kw 59 #34 MeSH descriptor: [Taenia] explode all trees 23 #35 MeSH descriptor: [Cestode Infections] this term only 1 #36 MeSH descriptor: [Taeniasis] explode all trees 71 #37 (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*):ti,ab,kw 175 #38 MeSH descriptor: [Hymenolepis] this term only 1 #39 MeSH descriptor: [Hymenolepis nana] this term only 2 #40 MeSH descriptor: [Hymenolepiasis] this term only 5 #41 (hymenolepi* or "h nana"):ti,ab,kw 23 #42 MeSH descriptor: [Enoplida Infections] explode all trees 142 #43 MeSH descriptor: [Trichuroidea] this term only 2 #44 MeSH descriptor: [Trichuris] this term only 70 #45 MeSH descriptor: [Trichinella] explode all trees 2 #46 (whipworm or "whip-worm" or trichuris or (trichocephalias* NEXT trichurias*) or "t trichiura"):ti,ab,kw 370 #47 (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis"):ti,ab,kw 11 #48 MeSH descriptor: [Enterobius] this term only 15 #49 MeSH descriptor: [Enterobiasis] this term only 9 #50 (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis"):ti,ab,kw 55 #51 MeSH descriptor: [Anisakiasis] this term only 2 #52 MeSH descriptor: [Anisakis] this term only 3 #53 MeSH descriptor: [Ascaridoidea] this term only 0 #54 MeSH descriptor: [Ascaridida Infections] this term only 0 #55 (anisakias* or anisakis or "pseudoterranova decipiens"):ti,ab,kw 8 #56 MeSH descriptor: [Angiostrongylus] this term only 0 #57 MeSH descriptor: [Strongylida Infections] this term only 2 #58 (angiostrongyl* or "a costaricensis" or "rat lung worm"):ti,ab,kw 5 #59 MeSH descriptor: [Fasciola] explode all trees 6 #60 MeSH descriptor: [Fascioliasis] this term only 11 #61 (fasciolias* or fasciola or "f hepatica" or "f giganta"):ti,ab,kw 29 #62 MeSH descriptor: [Opisthorchidae] explode all trees 17 #63 MeSH descriptor: [Clonorchiasis] this term only 11 #64 MeSH descriptor: [Opisthorchiasis] this term only 18 #65 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or (liver NEXT fluke*)):ti,ab,kw 61 #66 MeSH descriptor: [Gnathostomiasis] this term only 0 #67 MeSH descriptor: [Gnathostoma] this term only 7 #68 (gnathostomias* or gnathostoma or "g spinigerum"):ti,ab,kw 10 #69 MeSH descriptor: [Onchocerca] explode all trees 74 #70 MeSH descriptor: [Onchocerciasis] this term only 145 #71 (onchocercias* or onchocerca or "o volvulus"):ti,ab,kw 280 #72 MeSH descriptor: [Loiasis] this term only 14 #73 MeSH descriptor: [Loa] this term only 7 #74 (loias* or "loa loa"):ti,ab,kw 43 #75 MeSH descriptor: [Trichinellosis] this term only 6 #76 MeSH descriptor: [Trichinella] explode all trees 2 #77 (trichinella or trichinellias* or trichinellos* or "t spiralis"):ti,ab,kw 8 #78 ((swimmer* NEXT itch) or "cercarial dermatitis"):ti,ab,kw 1 #79 MeSH descriptor: [Sarcocystis] this term only 0 #80 MeSH descriptor: [Sarcocystosis] this term only 0 #81 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis):ti,ab,kw 0 #82 MeSH descriptor: [Sparganosis] this term only 0 #83 MeSH descriptor: [Sparganum] this term only 0 #84 (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum):ti,ab,kw 1 #85 MeSH descriptor: [Histoplasmosis] this term only 48 #86 MeSH descriptor: [Histoplasma] this term only 1 #87 (histoplasm* or "h capsulatum"):ti,ab,kw 129 #88 MeSH descriptor: [Talaromyces] this term only 2 #89 MeSH descriptor: [Penicillium] this term only 5 #90 (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei"):ti,ab,kw 48 #91 {OR #1-#90} 2740 #92 ("gold standard"):ti,ab,kw 7307 #93 MeSH descriptor: [Sensitivity and Specificity] explode all trees 16037 #94 (sensitivity or specificity or (("pre-test" or pretest) NEXT probability) or "post-test probability" or (predictive NEXT value*) or (likelihood NEXT ratio*)):ti,ab,kw 75588 #95 #92 or #93 or #94 82110 #96 #91 AND #95 138 WHO Global Index Medicus Database name: Global Index Medicus Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: 1056 EndNote import order: 10 Number of results once duplicates removed: 469 Search strategy notes: N/A (schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" OR ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" OR wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* OR paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR ("valley fever" not "rift valley fever") OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" OR "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" OR enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis OR clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" OR "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum OR histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei") AND ("gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*") AND ( la:("en")) WHO International Clinical Trials Registry Platform Database name: International Clinical Trials Registry Platform Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: Search 1: 165 Search 2: 57 Search 3: 113 Search 4: 15 Search 5: 35 Search 6: 13 Search 7: 56 Search 8: 0 Search 9: 27 EndNote import order: 11 Number of results once duplicates removed: 405 Search strategy notes: Multiple searches run on sub-set of pathogens due to limits on the length of searches. Results from each search uploaded to EndNote for deduplication. All other search options cleared. Recruitment status: ALL Search conducted on Advanced Search page. Search terms entered into ‘Condition’ field. Search 1: schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" Search 2: ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" Search 3: wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* Search 4: paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" Search 5: "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" Search 6: enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis Search 7: clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" Search 8: "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum Search 9: histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei" ClinicalTrials.gov Database name: ClinicalTrials.gov Database platform: Clinicaltrials.gov Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: Search 1: 25 Search 2: 16 Search 3: 23 Search 4: 13 Search 5: 6 Search 6: 3 Search 7: 5 Search 8: 0 Search 9: 0 EndNote import order: 12 Number of results once duplicates removed: 21 Search strategy notes: Multiple searches run on sub-set of pathogens due to limits on the length of searches. Results from each search uploaded to EndNote for deduplication. Search 1: Condition: schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 2: Condition: ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 3: Condition: wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 4: Condition: paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 5: Condition: "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 6: Condition: enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 7: Condition: clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 8: Condition: "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 9: Condition: histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei" AND Other terms: "gold standard" OR sensitivity OR specificity OR "pre-test probability" OR "pretest probability" OR "post-test probability" OR "predictive value*" OR "likelihood ratio*" Search 3: treatment RCTs of relevant pathogens For all searches the list of pathogens and resulting clinical conditions was agreed with the project team. The randomised controlled trials filter was derived from the filter published by SIGN.[2] OvidSP Medline ALL Database name: Medline ALL Database platform: OvidSP Dates of database coverage: 1946 to December 20, 2021 Date searched: 21 December 2021 Searched by: JF Number of results: 2692 EndNote import order: 1 (Medline) and 3 (Medline In Process) Number of results once duplicates removed: 2416 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type SH: subject heading word TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp Schistosomiasis/ 24379 2 exp Schistosoma/ 18038 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 29661 4 exp Ancylostomatoidea/ 2644 5 exp Hookworm Infections/ 4307 6 exp Ascaris/ 5465 7 Ascariasis/ 5728 8 exp Strongyloides/ 2681 9 Strongyloidiasis/ 3875 10 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 19212 11 exp Larva Migrans/ 1601 12 exp Toxocara/ 2319 13 Toxocariasis/ 1997 14 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 4918 15 Wuchereria bancrofti/ 2360 16 Brugia/ or Brugia malayi/ 2151 17 filariasis/ or elephantiasis, filarial/ 8466 18 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 9694 19 exp echinococcosis/ 20122 20 exp Echinococcus/ 6119 21 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 20568 22 Paragonimiasis/ 1157 23 exp Paragonimus/ 935 24 (paragonimiasis or paragonimus or p westermani).ti,ab. 1815 25 coccidioidomycosis/ or paracoccidioidomycosis/ 5007 26 blastomyces/ or coccidioides/ or paracoccidioides/ 3998 27 Blastomycosis/ 2671 28 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 8400 29 exp Taenia/ 4296 30 cestode infections/ or exp taeniasis/ 11487 31 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 14412 32 hymenolepis/ or hymenolepis nana/ 1086 33 Hymenolepiasis/ 1106 34 (hymenolepi* or h nana).ti,ab. 2847 35 exp enoplida infections/ 7632 36 trichuroidea/ or Trichuris/ or exp trichinella/ 5485 37 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 4180 38 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 6310 39 Enterobius/ 955 40 Enterobiasis/ 778 41 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 2054 42 Anisakiasis/ 760 43 Anisakis/ 889 44 Ascaridoidea/ 825 45 Ascaridida Infections/ 549 46 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 1659 47 Angiostrongylus/ 670 48 Strongylida Infections/ 2557 49 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 1900 50 exp Fasciola/ 4415 51 Fascioliasis/ 4039 52 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 6151 53 exp Opisthorchidae/ 1938 54 clonorchiasis/ or opisthorchiasis/ 2536 55 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 5217 56 Gnathostomiasis/ 126 57 Gnathostoma/ 446 58 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 622 59 exp Onchocerca/ 2345 60 Onchocerciasis/ 3879 61 (onchocercias* or onchocerca or o volvulus).ti,ab. 5169 62 Loiasis/ 620 63 Loa/ 529 64 (loias* or loa loa).ti,ab. 902 65 Trichinellosis/ 4998 66 exp Trichinella/ 3773 67 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 5083 68 (swimmer* itch or cercarial dermatitis).ti,ab. 268 69 Sarcocystis/ 1630 70 Sarcocystosis/ 1575 71 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 240 72 Sparganosis/ 493 73 Sparganum/ 252 74 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 982 75 Histoplasmosis/ or Histoplasma/ or (histoplasm* or h capsulatum).ti,ab. 9142 76 Talaromyces/ or Penicillium/ or (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 16303 77 or/1-76 182357 78 randomized controlled trial.pt. 553907 79 controlled clinical trial.pt. 94616 80 randomized.ab. 544699 81 placebo.ab. 224168 82 clinical trials as topic.sh. 198509 83 randomly.ab. 372486 84 trial.ti. 253389 85 or/78-84 1415240 86 77 and 85 4108 87 exp animals/ not humans.sh. 4932653 88 (comment or editorial or letter or news).pt. 2217165 89 87 or 88 7067818 90 86 not 89 3065 91 limit 90 to english language 2701 92 remove duplicates from 91 2692 OvidSP Embase Classic+Embase Database name: Embase Classic+Embase Database platform: OvidSP Dates of database coverage: 1947 to 2021 December 20 Date searched: 21 December 2021 Searched by: JF Number of results: 4399 EndNote import order: 2 Number of results once duplicates removed: 3330 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp schistosomiasis/ 28590 2 schistosoma/ or schistosoma haematobium/ or schistosoma japonicum/ or schistosoma mansoni/ 24637 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 34972 4 hookworm/ or exp ancylostoma/ or exp necator/ 6685 5 exp hookworm infection/ 5277 6 exp Ascaris/ or Ascaris lumbricoides/ 10473 7 ascariasis/ 6825 8 strongyloides/ or strongyloides stercoralis/ 5150 9 exp strongyloidiasis/ 5286 10 Loeffler pneumonia/ 5209 11 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 23989 12 exp larva migrans/ 2350 13 exp Toxocara/ 4182 14 toxocariasis/ 2849 15 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 5977 16 Wuchereria bancrofti/ 3392 17 brugia/ or brugia malayi/ or brugia timori/ 2714 18 filariasis/ 10070 19 Brugian filariasis/ 206 20 Bancroftian filariasis/ 219 21 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 11765 22 exp echinococcosis/ 24945 23 exp Echinococcus/ 10208 24 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 25373 25 paragonimiasis/ 1600 26 paragonimus/ or paragonimus westermani/ 1445 27 (paragonimiasis or paragonimus or p westermani).ti,ab. 2206 28 coccidioidomycosis/ 5449 29 South American blastomycosis/ 2538 30 exp Blastomyces/ 1155 31 exp Coccidioides/ 2838 32 paracoccidioides/ or paracoccidioides brasiliensis/ 2441 33 blastomycosis/ 4064 34 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 10812 35 taenia/ or taenia saginata/ or taenia solium/ 5858 36 cestodiasis/ or exp taeniasis/ 13021 37 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 16563 38 hymenolepis/ or hymenolepis nana/ 2056 39 hymenolepiasis/ 305 40 (hymenolepi* or h nana).ti,ab. 3329 41 trichuris/ or trichuris trichiura/ 4649 42 enoplid infection/ or trichinosis/ or trichuriasis/ 7598 43 trichinella/ or trichinella spiralis/ 5223 44 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 5260 45 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 7189 46 exp Enterobius/ 2657 47 enterobiasis/ 2385 48 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 2719 49 ascarid infection/ or anisakiasis/ 1197 50 anisakis/ 1471 51 Ascaridoidea/ 913 52 pseudoterranova decipiens/ 45 53 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 2179 54 angiostrongylus/ or angiostrongylus costaricensis/ 883 55 strongyle infection/ 680 56 angiostrongyliasis/ 629 57 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 2178 58 exp Fasciola/ 6624 59 fascioliasis/ 4732 60 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 7031 61 exp opisthorchiidae/ 2964 62 clonorchiasis/ 1172 63 opisthorchiasis/ 1817 64 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 5899 65 gnathostomiasis/ 329 66 exp gnathostoma/ 221 67 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 713 68 onchocerca/ or onchocerca volvulus/ 3197 69 exp onchocerciasis/ 6092 70 (onchocercias* or onchocerca or o volvulus).ti,ab. 5992 71 loiasis/ 457 72 exp Loa/ 1138 73 (loias* or loa loa).ti,ab. 1219 74 trichinosis/ 5003 75 trichinella/ or trichinella spiralis/ 5223 76 cercarial dermatitis/ 73 77 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 5925 78 (swimmer* itch or cercarial dermatitis).ti,ab. 344 79 exp Sarcocystis/ 1964 80 sarcocystosis/ 415 81 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 271 82 sparganosis/ 396 83 sparganum/ 249 84 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1089 85 exp histoplasmosis/ 10797 86 exp Histoplasma/ 5535 87 (histoplasm* or h capsulatum).ti,ab. 10975 88 talaromyces/ or talaromyces marneffei/ 1030 89 Penicillium/ 12384 90 penicilliosis/ 337 91 (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 17507 92 or/1-91 233276 93 controlled clinical trial/ 464942 94 exp randomized controlled trial/ 690982 95 multicenter study/ 308810 96 phase 3 clinical trial/ or phase 4 clinical trial/ 61870 97 exp randomization/ 92913 98 single blind procedure/ 44638 99 double blind procedure/ 193135 100 crossover procedure/ 69276 101 placebo/ 385368 102 randomi?ed controlled trial$.tw. 272658 103 rct.tw. 44718 104 (random$ adj2 allocat$).tw. 48619 105 single-blind$.tw. 28124 106 double-blind$.tw. 231249 107 ((treble or triple) adj blind$).tw. 1496 108 placebo$.tw. 340947 109 prospective study/ 735140 110 or/93-109 2233796 111 exp case study/ 92142 112 case report.tw. 496982 113 abstract report/ 89544 114 letter/ 1130594 115 editorial.pt. 711012 116 letter.pt. 1201304 117 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1131801 118 Animal experiment/ not (human experiment/ or human/) 2379156 119 or/111-118 4971064 120 110 not 119 2134649 121 92 and 120 4759 122 limit 121 to english language 4449 123 remove duplicates from 122 4399 OvidSP Global Health Database name: Global Health Database platform: OvidSP Dates of database coverage: 1910 to 2021 Week 50 Date searched: 21 December 2021 Searched by: JF Number of results: 954 EndNote import order: 4 Number of results once duplicates removed: 156 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp schistosomiasis/ 47979 2 schistosoma/ or schistosoma haematobium/ or schistosoma japonicum/ or schistosoma mansoni/ 51569 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 48480 4 hookworms/ 10934 5 ascaris/ or ascaris lumbricoides/ 17420 6 ascariasis/ 6669 7 strongyloides/ or strongyloides stercoralis/ 8523 8 strongyloidiasis/ 6089 9 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 34335 10 larva migrans/ 1673 11 toxocara/ or toxocara canis/ or toxocara cati/ 6694 12 toxocariasis/ 2691 13 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 7320 14 exp wuchereria bancrofti/ 7785 15 brugia/ or brugia malayi/ or brugia timori/ 5364 16 filariasis/ or bancroftian filariasis/ or brugian filariasis/ 21430 17 elephantiasis/ 2041 18 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 16691 19 exp echinococcosis/ 14560 20 echinococcus/ or echinococcus granulosus/ or echinococcus multilocularis/ 20269 21 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 18793 22 paragonimus/ or paragonimiasis/ or paragonimus westermani/ 4122 23 (paragonimiasis or paragonimus or p westermani).ti,ab. 4068 24 coccidioidomycosis/ 3144 25 paracoccidioidomycosis/ 1921 26 exp blastomyces/ 3846 27 exp coccidioides/ 4610 28 exp paracoccidioides/ 3464 29 blastomycosis/ 2119 30 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 10294 31 taenia/ or taenia saginata/ or taenia solium/ 16494 32 cestode infections/ or taeniasis/ 47612 33 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 18466 34 "hymenolepis (cestoda)"/ or hymenolepis nana/ 6758 35 (hymenolepi* or h nana).ti,ab. 6957 36 trichuris/ or trichuridae/ or trichuriasis/ 11666 37 trichinella/ or trichinella spiralis/ 12428 38 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 10474 39 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 11982 40 enterobius/ or enterobius vermicularis/ 5723 41 enterobiasis/ 2246 42 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 5716 43 anisakiasis/ 1107 44 exp anisakis/ 1826 45 ascaridiosis/ 567 46 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 1838 47 angiostrongylus/ or angiostrongylus costaricensis/ 2503 48 angiostrongyliasis/ 903 49 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 2516 50 exp fasciola/ 8521 51 fascioliasis/ 6350 52 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 8205 53 opisthorchiidae/ or exp clonorchis/ or exp opisthorchis/ 6402 54 clonorchiasis/ 1829 55 opisthorchiasis/ 1831 56 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 8088 57 gnathostoma/ or gnathostoma spinigerum/ or gnathostomiasis/ 914 58 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 909 59 onchocerca/ or onchocerca volvulus/ 9448 60 onchocerciasis/ 7260 61 (onchocercias* or onchocerca or o volvulus).ti,ab. 9152 62 exp loa/ 2065 63 (loias* or loa loa).ti,ab. 1724 64 trichinosis/ 7853 65 trichinella/ or trichinella spiralis/ 12428 66 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 10669 67 cercarial dermatitis/ 574 68 (swimmer* itch or cercarial dermatitis).ti,ab. 455 69 exp sarcocystis/ 1500 70 sarcocystosis/ 515 71 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 248 72 sparganosis/ 591 73 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1247 74 exp histoplasmosis/ 5301 75 histoplasma/ or histoplasma capsulatum/ 8434 76 (histoplasm* or h capsulatum).ti,ab. 9119 77 talaromyces/ or talaromyces marneffei/ 1071 78 (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 11853 79 or/1-78 222425 80 randomized controlled trials/ 50029 81 randomi?ed controlled trial$.tw. 60949 82 rct.tw. 3962 83 (random$ adj2 allocat$).tw. 6832 84 single-blind$.tw. 2736 85 double-blind$.tw. 27792 86 ((treble or triple) adj blind$).tw. 346 87 placebo$.tw. 41261 88 or/80-87 99359 89 case studies/ 21532 90 case report.tw. 24159 91 editorial.pt. 3035 92 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 533996 93 or/89-92 581789 94 88 not 93 95683 95 79 and 94 1102 96 limit 95 to english language 954 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: 1363 EndNote import order: 5 Number of results once duplicates removed: 1046 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract MH: thesaurus terms TI: title TW: textword Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (MH "Schistosomiasis") 1,178 S2 (TI (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) or (AB (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) 1,320 S3 (MH "Hookworm Infections") OR (MH "Strongylida Infections") 334 S4 (TI (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) or (AB (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) 1,229 S5 (MH "Larva Migrans") 110 S6 (MH "Toxocariasis") OR (MH "Ascariasis") OR (MH "Ascaridida Infections") 484 S7 (TI ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) or (AB ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) 331 S8 (MH "Elephantiasis, Filarial") OR (MH "Filariasis") 606 S9 (TI ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) or (AB ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) 636 S10 (MH "Echinococcosis+") 1,468 S11 (TI (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) or (AB (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) 1,643 S12 (MH "Paragonimiasis") 47 S13 (TI (paragonimiasis or paragonimus or "p westermani" )) or (AB (paragonimiasis or paragonimus or "p westermani" )) 72 S14 (MH "Coccidioidomycosis") 448 S15 (MH "Blastomycosis") 182 S16 (TI (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) or (AB (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) 801 S17 (MH "Taeniasis") 92 S18 (TI (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) or (AB (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) 913 S19 (MH "Cestode Infections") 71 S20 (TI (hymenolepi* or "h nana")) or (AB (hymenolepi* or "h nana")) 70 S21 (MH "Enoplida Infections+") 184 S22 (TI (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) or (AB (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) 221 S23 (TI (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) or (AB (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) 123 S24 (MH "Enterobiasis") 127 S25 (TI (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) or (AB (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) 181 S26 (MH "Ascaridida Infections") OR (MH "Ascariasis") 351 S27 (TI (anisakias* or anisakis or "pseudoterranova decipiens")) or (AB (anisakias* or anisakis or "pseudoterranova decipiens")) 90 S28 (MH "Strongylida Infections") 123 S29 (TI (angiostrongyl* or "a costaricensis" or "rat lung worm")) or (AB (angiostrongyl* or "a costaricensis" or "rat lung worm")) 78 S30 (MH "Fascioliasis") 124 S31 (TI (fasciolias* or fasciola or "f hepatica" or "f giganta")) or (AB (fasciolias* or fasciola or "f hepatica" or "f giganta")) 138 S32 (MH "Clonorchiasis") OR (MH "Opisthorchiasis") 51 S33 (TI (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) or (AB (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) 144 S34 (TI (gnathostomias* or gnathostoma or "g spinigerum")) or (AB (gnathostomias* or gnathostoma or "g spinigerum")) 41 S35 (MH "Onchocerciasis+") 244 S36 (TI (onchocercias* or onchocerca or "o volvulus")) or (AB (onchocercias* or onchocerca or "o volvulus")) 323 S37 (TI (loias* or "loa loa")) or (AB (loias* or "loa loa")) 80 S38 (TI (trichinella or trichinellias* or trichinellos* or "t spiralis")) or (AB (trichinella or trichinellias* or trichinellos* or "t spiralis")) 92 S39 (TI ("swimmer* itch" or "cercarial dermatitis")) or (AB ("swimmer* itch" or "cercarial dermatitis")) 22 S40 (TI (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) or (AB (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) 16 S41 (MH "Sparganosis") 40 S42 (TI (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) or (AB (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) 56 S43 (MH "Histoplasmosis") 682 S44 (TI (histoplasm* or "h capsulatum")) or (AB (histoplasm* or "h capsulatum")) 756 S45 (TI (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) or (AB (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) 527 S46 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45 10,174 S47 (MH "Clinical Trials") 182,193 S48 (PT "Clinical Trial") 111,552 S49 TX clinic* n1 trial* 430,608 S50 (TX ((singl* or doubl* or tripl* or trebl*) N1 (blind* or mask*))) 1,265,840 S51 TX "randomi* control* trial*" 309,223 S52 (MH "Random Assignment") 71,895 S53 (TX (random* N1 allocat*)) 20,993 S54 TX placebo* 134,227 S55 (MH "Placebos") 13,492 S56 (MH "Quantitative Studies") 30,851 S57 S47 OR S48 OR S49 OR S50 OR S51 OR S52 OR S53 OR S54 OR S55 OR S56 1,783,935 S58 S46 AND S57 1,642 S59 (MH "Animals+") 100,150 S60 (MH "Animal Studies") 143,223 S61 (TI "animal model*") 3,298 S62 S59 OR S60 OR S61 234,609 S63 (MH human) 2,488,275 S64 S62 not S63 202,341 S65 S58 not S64 1,515 S66 S65 Limiters - Language: English 1,363 EBSCOhost Africa-Wide Information Database name: Africa-Wide Information Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: 1042 EndNote import order: 6 Number of results once duplicates removed: 253 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TX: textword * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (TI (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) or (AB (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) 23,392 S2 (TI (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) or (AB (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) 6,732 S3 (TI ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) or (AB ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) 1,519 S4 (TI ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) or (AB ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) 11,968 S5 (TI (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) or (AB (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) 3,570 S6 (TI (paragonimiasis or paragonimus or "p westermani" )) or (AB (paragonimiasis or paragonimus or "p westermani" )) 513 S7 (TI (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) or (AB (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) 662 S8 (TI (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) or (AB (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) 7,308 S9 (TI (hymenolepi* or "h nana")) or (AB (hymenolepi* or "h nana")) 1,658 S10 (TI (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) or (AB (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) 2,493 S11 (TI (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) or (AB (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) 1,222 S12 (TI (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) or (AB (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) 583 S13 (TI (anisakias* or anisakis or "pseudoterranova decipiens")) or (AB (anisakias* or anisakis or "pseudoterranova decipiens")) 336 S14 (TI (angiostrongyl* or "a costaricensis" or "rat lung worm")) or (AB (angiostrongyl* or "a costaricensis" or "rat lung worm")) 364 S15 (TI (fasciolias* or fasciola or "f hepatica" or "f giganta")) or (AB (fasciolias* or fasciola or "f hepatica" or "f giganta")) 1,909 S16 (TI (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) or (AB (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) 1,126 S17 (TI (gnathostomias* or gnathostoma or "g spinigerum")) or (AB (gnathostomias* or gnathostoma or "g spinigerum")) 135 S18 (TI (onchocercias* or onchocerca or "o volvulus")) or (AB (onchocercias* or onchocerca or "o volvulus")) 5,932 S19 (TI (loias* or "loa loa")) or (AB (loias* or "loa loa")) 919 S20 (TI (trichinella or trichinellias* or trichinellos* or "t spiralis")) or (AB (trichinella or trichinellias* or trichinellos* or "t spiralis")) 1,106 S21 (TI ("swimmer* itch" or "cercarial dermatitis")) or (AB ("swimmer* itch" or "cercarial dermatitis")) 100 S22 (TI (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) or (AB (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) 130 S23 (TI (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) or (AB (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) 371 S24 (TI (histoplasm* or "h capsulatum")) or (AB (histoplasm* or "h capsulatum")) 1,062 S25 (TI (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) or (AB (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) 1,522 S26 S1 or S2 or S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 63,223 S27 TX clinic* n1 trial* 24,438 S28 (TX ((singl* or doubl* or tripl* or trebl*) N1 (blind* or mask*))) 6,992 S29 TX "randomi* control* trial*" 13,467 S30 (TX (random* N1 allocat*)) 3,768 S31 TX placebo* 8,033 S32 S27 OR S28 OR S29 OR S30 OR S31 43,387 S33 S26 AND S32 1,190 S34 (TI (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*)) 85,119 S35 (TX (man or human)) 654,678 S36 S34 not S35 72,284 S37 S33 not S36 1,109 S38 S37 Limiters - Language: English 1,042 Clarivate Analytics Web of Science, Science Citation Index Database name: Science Citation Index-Expanded Database platform: Clarivate Analytics Web of Science Dates of database coverage: 1970-present Date searched: 21 December 2021 Searched by: JF Number of results: 1391 EndNote import order: 7 Number of results once duplicates removed: 430 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 30 #28 NOT #29 and Letters or Editorial Materials or Notes (Exclude – Document Types) and English (Languages) 1,391 29 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 2,337,839 28 #1 AND #27 1,616 27 #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 125,324 26 TI= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") or AB= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") 23,358 25 TI=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") or AB=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") 14,654 24 TI=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") or AB=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") 3,985 23 TI=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") or AB=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") 7,010 22 TI=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") or AB=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") 12,965 21 TI=("paragonimiasis" or "paragonimus" or "p westermani") or AB=("paragonimiasis" or "paragonimus" or "p westermani") 998 20 TI=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") or AB=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") 6,631 19 TI=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") or AB=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") 12,540 18 TI=("hymenolepi*" or "h nana") or AB=("hymenolepi*" or "h nana") 2,220 17 TI=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") or AB=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") 3,384 16 TI=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") or AB=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") 4,429 15 TI=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") or AB=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") 1,139 14 TI=("anisakias*" or "anisakis" or "pseudoterranova decipiens") or AB=("anisakias*" or "anisakis" or "pseudoterranova decipiens") 1,863 13 TI=("angiostrongyl*" or "a costaricensis" or "rat lung worm") or AB=("angiostrongyl*" or "a costaricensis" or "rat lung worm") 1,587 12 TI=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") or AB=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") 5,294 11 TI=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") or AB=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") 3,641 10 TI=("gnathostomias*" or "gnathostoma" or "g spinigerum") or AB=("gnathostomias*" or "gnathostoma" or "g spinigerum") 419 9 TI=("onchocercias*" or "onchocerca" or "o volvulus") or AB=("onchocercias*" or "onchocerca" or "o volvulus") 4,574 8 TI=("loias*" or "loa loa") or AB=("loias*" or "loa loa") 723 7 TI=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") or AB=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") 4,026 6 TI=("swimmer* itch" or "cercarial dermatitis") or AB=("swimmer* itch" or "cercarial dermatitis") 192 5 TI=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") or AB=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") 162 4 TI=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") or AB=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") 733 3 TI=("histoplasm*" or "h capsulatum") or AB=("histoplasm*" or "h capsulatum") 5,430 2 TI=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") or AB=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") 21,043 1 TS=((clinic* NEAR/1 trial*) or ((trebl* or tripl* or doubl* or singl*) NEAR/1 (blind* or mask*)) or "randomi* control* trial*" or (random* NEAR/1 allocat*) or placebo*) 990,093 Clarivate Analytics Web of Science SciELO Database name: SciELO Database platform: Clarivate Analytics Web of Science Dates of database coverage: 2002-present Date searched: 21 December 2021 Searched by: JF Number of results: 15 EndNote import order: 8 Number of results once duplicates removed: 2 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 28 #1 AND #27 and English (Languages) 15 27 #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24 OR #25 OR #26 4,504 26 TI= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") or AB= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") 859 25 TI=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") or AB=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") 736 24 TI=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") or AB=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") 334 23 TI=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") or AB=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") 103 22 TI=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") or AB=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") 294 21 TI=("paragonimiasis" or "paragonimus" or "p westermani") or AB=("paragonimiasis" or "paragonimus" or "p westermani") 21 20 TI=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") or AB=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") 395 19 TI=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") or AB=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") 481 18 TI=("hymenolepi*" or "h nana") or AB=("hymenolepi*" or "h nana") 100 17 TI=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") or AB=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") 256 16 TI=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") or AB=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") 62 15 TI=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") or AB=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") 101 14 TI=("anisakias*" or "anisakis" or "pseudoterranova decipiens") or AB=("anisakias*" or "anisakis" or "pseudoterranova decipiens") 79 13 TI=("angiostrongyl*" or "a costaricensis" or "rat lung worm") or AB=("angiostrongyl*" or "a costaricensis" or "rat lung worm") 109 12 TI=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") or AB=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") 251 11 TI=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") or AB=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") 24 10 TI=("gnathostomias*" or "gnathostoma" or "g spinigerum") or AB=("gnathostomias*" or "gnathostoma" or "g spinigerum") 22 9 TI=("onchocercias*" or "onchocerca" or "o volvulus") or AB=("onchocercias*" or "onchocerca" or "o volvulus") 43 8 TI=("loias*" or "loa loa") or AB=("loias*" or "loa loa") 8 7 TI=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") or AB=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") 54 6 TI=("swimmer* itch" or "cercarial dermatitis") or AB=("swimmer* itch" or "cercarial dermatitis") 1 5 TI=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") or AB=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") 3 4 TI=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") or AB=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") 24 3 TI=("histoplasm*" or "h capsulatum") or AB=("histoplasm*" or "h capsulatum") 280 2 TI=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") or AB=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") 654 1 TS=((clinic* NEAR/1 trial*) or ((trebl* or tripl* or double* or singl*) NEAR/1 (blind* or mask*)) or "randomi* control* trial*" or (random* NEAR/1 allocat*) or placebo*) 8,311 Wiley Cochrane Central Register of Controlled Trials Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 12 of 12, December 2021 Date searched: 21 December 2021 Searched by: JF Number of results: 2704 EndNote import order: 9 Number of results once duplicates removed: 782 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. ID Search Hits #1 MeSH descriptor: [Schistosomiasis] explode all trees 333 #2 MeSH descriptor: [Schistosoma] explode all trees 153 #3 (schistosomiasis or schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium"):ti,ab,kw 728 #4 MeSH descriptor: [Ancylostomatoidea] explode all trees 49 #5 MeSH descriptor: [Hookworm Infections] explode all trees 159 #6 MeSH descriptor: [Ascaris] explode all trees 83 #7 MeSH descriptor: [Ascariasis] this term only 152 #8 MeSH descriptor: [Strongyloides] explode all trees 19 #9 MeSH descriptor: [Strongyloidiasis] this term only 41 #10 (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis"):ti,ab,kw 738 #11 MeSH descriptor: [Larva Migrans] explode all trees 4 #12 MeSH descriptor: [Toxocara] explode all trees 1 #13 MeSH descriptor: [Toxocariasis] this term only 4 #14 ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*):ti,ab,kw 32 #15 MeSH descriptor: [Wuchereria bancrofti] this term only 102 #16 MeSH descriptor: [Brugia] this term only 6 #17 MeSH descriptor: [Brugia malayi] this term only 11 #18 MeSH descriptor: [Filariasis] this term only 90 #19 MeSH descriptor: [Elephantiasis, Filarial] this term only 134 #20 ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis):ti,ab,kw 406 #21 MeSH descriptor: [Echinococcosis] explode all trees 57 #22 MeSH descriptor: [Echinococcus] explode all trees 11 #23 (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis):ti,ab,kw 133 #24 MeSH descriptor: [Paragonimiasis] this term only 4 #25 MeSH descriptor: [Paragonimus] explode all trees 1 #26 (paragonimiasis or paragonimus or "p westermani"):ti,ab,kw 6 #27 MeSH descriptor: [Coccidioidomycosis] this term only 17 #28 MeSH descriptor: [Paracoccidioidomycosis] this term only 5 #29 MeSH descriptor: [Blastomyces] this term only 0 #30 MeSH descriptor: [Coccidioides] this term only 4 #31 MeSH descriptor: [Paracoccidioides] this term only 0 #32 MeSH descriptor: [Blastomycosis] this term only 5 #33 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or (paracoccidioidal NEXT granuloma*) or blastomycosis or blastomyces):ti,ab,kw 59 #34 MeSH descriptor: [Taenia] explode all trees 23 #35 MeSH descriptor: [Cestode Infections] this term only 1 #36 MeSH descriptor: [Taeniasis] explode all trees 71 #37 (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*):ti,ab,kw 175 #38 MeSH descriptor: [Hymenolepis] this term only 1 #39 MeSH descriptor: [Hymenolepis nana] this term only 2 #40 MeSH descriptor: [Hymenolepiasis] this term only 5 #41 (hymenolepi* or "h nana"):ti,ab,kw 23 #42 MeSH descriptor: [Enoplida Infections] explode all trees 142 #43 MeSH descriptor: [Trichuroidea] this term only 2 #44 MeSH descriptor: [Trichuris] this term only 70 #45 MeSH descriptor: [Trichinella] explode all trees 2 #46 (whipworm or "whip-worm" or trichuris or (trichocephalias* NEXT trichurias*) or "t trichiura"):ti,ab,kw 370 #47 (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis"):ti,ab,kw 11 #48 MeSH descriptor: [Enterobius] this term only 15 #49 MeSH descriptor: [Enterobiasis] this term only 9 #50 (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis"):ti,ab,kw 55 #51 MeSH descriptor: [Anisakiasis] this term only 2 #52 MeSH descriptor: [Anisakis] this term only 3 #53 MeSH descriptor: [Ascaridoidea] this term only 0 #54 MeSH descriptor: [Ascaridida Infections] this term only 0 #55 (anisakias* or anisakis or "pseudoterranova decipiens"):ti,ab,kw 8 #56 MeSH descriptor: [Angiostrongylus] this term only 0 #57 MeSH descriptor: [Strongylida Infections] this term only 2 #58 (angiostrongyl* or "a costaricensis" or "rat lung worm"):ti,ab,kw 5 #59 MeSH descriptor: [Fasciola] explode all trees 6 #60 MeSH descriptor: [Fascioliasis] this term only 11 #61 (fasciolias* or fasciola or "f hepatica" or "f giganta"):ti,ab,kw 29 #62 MeSH descriptor: [Opisthorchidae] explode all trees 17 #63 MeSH descriptor: [Clonorchiasis] this term only 11 #64 MeSH descriptor: [Opisthorchiasis] this term only 18 #65 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or (liver NEXT fluke*)):ti,ab,kw 61 #66 MeSH descriptor: [Gnathostomiasis] this term only 0 #67 MeSH descriptor: [Gnathostoma] this term only 7 #68 (gnathostomias* or gnathostoma or "g spinigerum"):ti,ab,kw 10 #69 MeSH descriptor: [Onchocerca] explode all trees 74 #70 MeSH descriptor: [Onchocerciasis] this term only 145 #71 (onchocercias* or onchocerca or "o volvulus"):ti,ab,kw 280 #72 MeSH descriptor: [Loiasis] this term only 14 #73 MeSH descriptor: [Loa] this term only 7 #74 (loias* or "loa loa"):ti,ab,kw 43 #75 MeSH descriptor: [Trichinellosis] this term only 6 #76 MeSH descriptor: [Trichinella] explode all trees 2 #77 (trichinella or trichinellias* or trichinellos* or "t spiralis"):ti,ab,kw 8 #78 ((swimmer* NEXT itch) or "cercarial dermatitis"):ti,ab,kw 1 #79 MeSH descriptor: [Sarcocystis] this term only 0 #80 MeSH descriptor: [Sarcocystosis] this term only 0 #81 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis):ti,ab,kw 0 #82 MeSH descriptor: [Sparganosis] this term only 0 #83 MeSH descriptor: [Sparganum] this term only 0 #84 (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum):ti,ab,kw 1 #85 MeSH descriptor: [Histoplasmosis] this term only 48 #86 MeSH descriptor: [Histoplasma] this term only 1 #87 (histoplasm* or "h capsulatum"):ti,ab,kw 129 #88 MeSH descriptor: [Talaromyces] this term only 2 #89 MeSH descriptor: [Penicillium] this term only 5 #90 (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei"):ti,ab,kw 48 #91 {OR #1-#90} 2740 WHO Global Index Medicus Database name: Global Index Medicus Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: 60 EndNote import order: 10 Number of results once duplicates removed: 17 Search strategy notes: N/A (schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" OR ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" OR wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* OR paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR ("valley fever" not "rift valley fever") OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" OR "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" OR enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis OR clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" OR "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum OR histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei") AND ("clinic* trial*" or "trebl* blind*" or "trebl* mask*" or "tripl* blind*" or "tripl* mask*" or "double* blind*" or "double* mask*" or "singl* blind*" or "singl* mask*" or "randomi* control* trial*" or "random allocat*" or "allocat* random" or placebo*) AND ( la:("en")) WHO International Clinical Trials Registry Platform Database name: International Clinical Trials Registry Platform Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: Search 1: 165 Search 2: 57 Search 3: 113 Search 4: 15 Search 5: 35 Search 6: 13 Search 7: 56 Search 8: 0 Search 9: 27 EndNote import order: 11 Number of results once duplicates removed: 405 Search strategy notes: Multiple searches run on sub-set of pathogens due to limits on the length of searches. Results from each search uploaded to EndNote for deduplication. All other search options cleared. Recruitment status: ALL Search conducted on Advanced Search page. Search terms entered into ‘Condition’ field. Search 1: schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" Search 2: ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" Search 3: wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* Search 4: paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" Search 5: "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" Search 6: enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis Search 7: clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" Search 8: "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum Search 9: histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei" ClinicalTrials.gov Database name: ClinicalTrials.gov Database platform: Clinicaltrials.gov Dates of database coverage: Complete database to search date Date searched: 21 December 2021 Searched by: JF Number of results: Search 1: 128 Search 2: 47 Search 3: 98 Search 4: 55 Search 5: 46 Search 6: 5 Search 7: 12 Search 8: 0 Search 9: 4 EndNote import order: 12 Number of results once duplicates removed: 52 Search strategy notes: Multiple searches run on sub-set of pathogens due to limits on the length of searches. Results from each search uploaded to EndNote for deduplication. Search 1: Condition: schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" Search 2: Condition: ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" Search 3: Condition: wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* Search 4: Condition: paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" Search 5: Condition: "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" Search 6: Condition: enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis Search 7: Condition: clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" Search 8: Condition: "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum Search 9: Condition: histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei" Search 3a: treatment based randomised controlled trials of eosinophilic meningitis The randomised controlled trials filter was derived from the filter published by SIGN.[2] Results from this search were deduplicated together with results from searches 3 and 3b. OvidSP Medline ALL Database name: Medline ALL Database platform: OvidSP Dates of database coverage: 1946 to October 04, 2022 Date searched: 05 October 2022 Searched by: JF Number of results: 7 EndNote import order: 1 Number of results once duplicates removed: 2 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type SH: subject heading word TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 Meningitis/ 19789 2 exp Eosinophilia/ 26824 3 1 and 2 288 4 eosinophi* meningitis.ti,ab. 583 5 3 or 4 643 6 randomized controlled trial.pt. 578735 7 controlled clinical trial.pt. 95070 8 randomized.ab. 578561 9 placebo.ab. 232393 10 clinical trials as topic.sh. 200438 11 randomly.ab. 393034 12 trial.ti. 271916 13 or/6-12 1478206 14 5 and 13 9 15 exp animals/ not humans.sh. 5053949 16 (comment or editorial or letter or news).pt. 2298090 17 15 or 16 7267647 18 14 not 17 9 19 limit 18 to english language 8 20 remove duplicates from 19 7 21 limit 20 to medline 7 OvidSP Embase Classic+Embase Database name: Embase Classic+Embase Database platform: OvidSP Dates of database coverage: 1947 to 2022 October 04 Date searched: 05 October 2022 Searched by JF Number of results: 21 EndNote import order: 2 Number of results once duplicates removed: 7 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 eosinophilic meningitis/ 183 2 eosinophi* meningitis.ti,ab. 684 3 1 or 2 730 4 controlled clinical trial/ 467672 5 exp randomized controlled trial/ 735037 6 multicenter study/ 338892 7 phase 3 clinical trial/ or phase 4 clinical trial/ 67912 8 exp randomization/ 95828 9 single blind procedure/ 47828 10 double blind procedure/ 202019 11 crossover procedure/ 71994 12 placebo/ 396979 13 randomi?ed controlled trial$.tw. 296803 14 rct.tw. 48942 15 (random$ adj2 allocat$).tw. 51659 16 single-blind$.tw. 29767 17 double-blind$.tw. 239817 18 ((treble or triple) adj blind$).tw. 1687 19 placebo$.tw. 355032 20 prospective study/ 802133 21 or/4-20 2379897 22 exp case study/ 98276 23 case report.tw. 525811 24 abstract report/ 89393 25 letter/ 1165317 26 editorial.pt. 739453 27 letter.pt. 1241856 28 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1169096 29 Animal experiment/ not (human experiment/ or human/) 2457406 30 or/22-29 5156588 31 21 not 30 2275312 32 3 and 31 21 33 limit 32 to english language 21 34 remove duplicates from 33 21 OvidSP Global Health Database name: Global Health Database platform: OvidSP Dates of database coverage: 1910 to 2022 Week 39 Date searched: 05 October 2022 Searched by: JF Number of results: 1 EndNote import order: 3 Number of results once duplicates removed: 0 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp eosinophilia/ 5578 2 meningitis/ 19038 3 1 and 2 155 4 eosinophi* meningitis.ti,ab. 580 5 3 or 4 631 6 randomized controlled trials/ 55672 7 randomi?ed controlled trial$.tw. 67144 8 rct.tw. 4461 9 (random$ adj2 allocat$).tw. 7303 10 single-blind$.tw. 2948 11 double-blind$.tw. 29116 12 ((treble or triple) adj blind$).tw. 404 13 placebo$.tw. 43314 14 or/6-13 106869 15 case studies/ 23900 16 case report.tw. 25878 17 editorial.pt. 3049 18 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 552318 19 or/15-18 604144 20 14 not 19 102903 21 3 and 20 1 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 05 October 2022 Searched by: JF Number of results: 8 EndNote import order: 4 Number of results once duplicates removed: 4 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract MH: thesaurus terms TI: title TW: textword Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (MH "Eosinophilia+") 3,648 S2 (MH "Meningitis") 3,354 S3 S1 AND S2 37 S4 (TI "eosinophi* meningitis") OR (AB "eosinophi* meningitis") 63 S5 S3 OR S4 72 S6 (MH "Clinical Trials") 186,417 S7 (PT "Clinical Trial") 113,700 S8 TX clinic* n1 trial* 452,012 S9 (TX ((singl* or doubl* or tripl* or trebl*) N1 (blind* or mask*))) 1,310,276 S10 TX "randomi* control* trial*" 330,436 S11 (MH "Random Assignment") 75,876 S12 (TX (random* N1 allocat*)) 22,383 S13 TX placebo* 140,103 S14 (MH "Placebos") 13,822 S15 (MH "Quantitative Studies") 33,089 S16 S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 1,857,918 S17 S5 AND S16 9 S18 (MH "Animals+") 104,284 S19 (MH "Animal Studies") 149,301 S20 (TI "animal model*") 3,445 S21 S18 OR S19 OR S20 244,671 S22 (MH human) 2,608,213 S23 S21 NOT S22 210,987 S24 S17 NOT S23 8 S25 S24 Limiters - English Language 8 EBSCOhost Africa-Wide Information Database name: Africa-Wide Information Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 05 October 2022 Searched by: JF Number of results: 1 EndNote import order: 5 Number of results once duplicates removed: 0 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TX: textword * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (TI "eosinophi* meningitis") OR (AB "eosinophi* meningitis") 99 S2 TX clinic* n1 trial* 24,885 S3 (TX ((singl* or doubl* or tripl* or trebl*) N1 (blind* or mask*))) 7,147 S4 TX "randomi* control* trial*" 13,938 S5 (TX (random* N1 allocat*)) 3,885 S6 TX placebo* 8,172 S7 S2 OR S3 OR S4 OR S5 OR S6 44,308 S8 S1 AND S7 1 Clarivate Analytics Web of Science, Science Citation Index Database name: Science Citation Index-Expanded Database platform: Clarivate Analytics Web of Science Dates of database coverage: 1970-present Date searched: 05 October 2022 Searched by: JF Number of results: 6 EndNote import order: 6 Number of results once duplicates removed: 0 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 5 #3 NOT #4 6 4 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 2,379,179 3 #2 AND #1 6 2 TS=((clinic* NEAR/1 trial*) or ((trebl* or tripl* or doubl* or singl*) NEAR/1 (blind* or mask*)) or "randomi* control* trial*" or (random* NEAR/1 allocat*) or placebo*) 1,046,704 1 TI=("eosinophili* meningitis") OR AB=("eosinophili* meningitis") 445 Clarivate Analytics Web of Science SciELO Database name: SciELO Database platform: Clarivate Analytics Web of Science Dates of database coverage: 2002-present Date searched: 05 October 2022 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: N/A Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("eosinophili* meningitis") OR AB=("eosinophili* meningitis") 25 2 TS=((clinic* NEAR/1 trial*) or ((trebl* or tripl* or doubl* or singl*) NEAR/1 (blind* or mask*)) or "randomi* control* trial*" or (random* NEAR/1 allocat*) or placebo*) 8,935 3 #2 AND #1 0 Wiley Cochrane Central Register of Controlled Trials Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 10 of 12, October 2022 Date searched: 05 October 2022 Searched by: JF Number of results: 5 EndNote import order: 7 Number of results once duplicates removed: 0 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. ID Search Hits #1 MeSH descriptor: [Meningitis] this term only 307 #2 MeSH descriptor: [Eosinophilia] explode all trees 442 #3 #1 AND #2 4 #4 (eosinophi* NEXT meningitis):ti,ab,kw 5 #5 #3 OR #4 6 WHO Global Index Medicus Database name: Global Index Medicus Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 05 October 2022 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: N/A eosinophi* meningitis AND ("clinic* trial*" or "trebl* blind*" or "trebl* mask*" or "tripl* blind*" or "tripl* mask*" or "double* blind*" or "double* mask*" or "singl* blind*" or "singl* mask*" or "randomi* control* trial*" or "random allocat*" or "allocat* random" or placebo*) WHO International Clinical Trials Registry Platform Database name: International Clinical Trials Registry Platform Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 05 October 2022 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: All other search options cleared. Recruitment status: ALL Search conducted on Advanced Search page. Search terms entered into ‘Condition’ field. eosinophilic meningitis ClinicalTrials.gov Database name: ClinicalTrials.gov Database platform: Clinicaltrials.gov Dates of database coverage: Complete database to search date Date searched: 05 October 2022 Searched by: JF Number of results: 2 EndNote import order: 8 Number of results once duplicates removed: 2 Search strategy notes: Search run in ‘Condition’ field eosinophilic meningitis Search 3b: treatment RCTs for cystoisospora The randomised controlled trials filter was derived from the filter published by SIGN.[2] Results from this search were deduplicated together with results from searches 3 and 3a. OvidSP Medline ALL Database name: Medline ALL Database platform: OvidSP Dates of database coverage: 1946 to February 24, 2023 Date searched: 2023-02-27 Searched by: JF Number of results: 7 EndNote import order: 1 Number of results once duplicates removed: 6 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type SH: subject heading word TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 Isosporiasis/ 252 2 Isospora/ 795 3 (cystoisospora belli or isospora belli).ti,ab. 467 4 (cystoisosporiasis or isosporiasis).ti,ab. 158 5 or/1-4 1184 6 randomized controlled trial.pt. 587462 7 controlled clinical trial.pt. 95197 8 randomized.ab. 593836 9 placebo.ab. 235995 10 clinical trials as topic.sh. 200883 11 randomly.ab. 402634 12 trial.ti. 279993 13 or/6-12 1505934 14 5 and 13 26 15 exp animals/ not humans.sh. 5096339 16 (comment or editorial or letter or news).pt. 2335094 17 15 or 16 7346302 18 14 not 17 8 19 limit 18 to english language 7 OvidSP Embase Classic+Embase Database name: Embase Classic+Embase Database platform: OvidSP Dates of database coverage: 1947 to 2023 February 24 Date searched: 2023-02-27 Searched by: JF Number of results: 36 EndNote import order: 2 Number of results once duplicates removed: 15 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 cystoisospora/ or isospora belli/ 568 2 isosporiasis/ 277 3 (cystoisospora belli or isospora belli).ti,ab. 548 4 (cystoisosporiasis or isosporiasis).ti,ab. 174 5 or/1-4 1045 6 controlled clinical trial/ 469069 7 exp randomized controlled trial/ 776809 8 multicenter study/ 368927 9 phase 3 clinical trial/ or phase 4 clinical trial/ 72950 10 exp randomization/ 98899 11 single blind procedure/ 50942 12 double blind procedure/ 210391 13 crossover procedure/ 74675 14 placebo/ 410181 15 randomi?ed controlled trial$.tw. 319058 16 rct.tw. 52478 17 (random$ adj2 allocat$).tw. 54105 18 single-blind$.tw. 31380 19 double-blind$.tw. 248212 20 ((treble or triple) adj blind$).tw. 1853 21 placebo$.tw. 369165 22 prospective study/ 860124 23 or/6-22 2513184 24 exp case study/ 106438 25 case report.tw. 550246 26 abstract report/ 89405 27 letter/ 1216981 28 editorial.pt. 766197 29 letter.pt. 1293076 30 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1214754 31 Animal experiment/ not (human experiment/ or human/) 2554515 32 or/24-31 5367059 33 23 not 32 2402766 34 5 and 33 46 35 limit 34 to english language 36 36 remove duplicates from 35 36 OvidSP Global Health Database name: Global Health Database platform: OvidSP Dates of database coverage: 1910 to 2023 week 08 Date searched: 2023-02-27 Searched by: JF Number of results: 4 EndNote import order: 3 Number of results once duplicates removed: 2 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 isospora/ or isospora belli/ 1778 2 isosporiasis/ 554 3 (cystoisospora belli or isospora belli).ti,ab. 651 4 (cystoisosporiasis or isosporiasis).ti,ab. 148 5 or/1-4 1862 6 randomized controlled trials/ 58091 7 randomi?ed controlled trial$.tw. 69972 8 rct.tw. 4672 9 (random$ adj2 allocat$).tw. 7482 10 single-blind$.tw. 3035 11 double-blind$.tw. 29695 12 ((treble or triple) adj blind$).tw. 430 13 placebo$.tw. 44276 14 or/6-13 110162 15 case studies/ 24963 16 case report.tw. 26472 17 editorial.pt. 3051 18 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 560868 19 or/15-18 614328 20 14 not 19 106085 21 5 and 20 4 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 2023-02-27 Searched by: JF Number of results: 6 EndNote import order: 4 Number of results once duplicates removed: 4 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract MH: thesaurus terms TI: title TW: textword Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (TI ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) or (AB ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) 50 S2 (MH "Clinical Trials") 187,936 S3 (PT "Clinical Trial") 114,646 S4 TX clinic* n1 trial* 460,783 S5 (TX ((singl* or doubl* or tripl* or trebl*) N1 (blind* or mask*))) 1,331,941 S6 TX "randomi* control* trial*" 339,605 S7 (MH "Random Assignment") 78,022 S8 (TX (random* N1 allocat*)) 22,955 S9 TX placebo* 142,000 S10 (MH "Placebos") 13,985 S11 (MH "Quantitative Studies") 34,468 S12 S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 1,892,931 S13 S1 AND S12 7 S14 (MH "Animals+") 105,370 S15 (MH "Animal Studies") 151,483 S16 (TI "animal model*") 3,512 S17 S14 OR S15 OR S16 247,877 S18 (MH human) 2,659,438 S19 S17 NOT S18 213,917 S20 S13 NOT S19 6 S21 S20 Limiters - English Language 6 EBSCOhost Africa-Wide Information Database name: Africa-Wide Information Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 2023-02-27 Searched by: JF Number of results: 4 EndNote import order: 5 Number of results once duplicates removed: 1 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TX: textword * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (TI ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) or (AB ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) 184 S2 TX clinic* n1 trial* 25,277 S3 (TX ((singl* or doubl* or tripl* or trebl*) N1 (blind* or mask*))) 7,202 S4 TX "randomi* control* trial*" 14,023 S5 (TX (random* N1 allocat*)) 3,902 S6 TX placebo* 8,252 S7 S2 OR S3 OR S4 OR S5 OR S6 44,837 S8 S1 AND S7 4 Clarivate Analytics Web of Science, Science Citation Index Database name: Science Citation Index-Expanded Database platform: Clarivate Analytics Web of Science Dates of database coverage: 1970-present Date searched: 2023-02-27 Searched by: JF Number of results: 7 EndNote import order: 6 Number of results once duplicates removed: 2 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) or AB=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) 371 2 TS=((clinic* NEAR/1 trial*) or ((trebl* or tripl* or doubl* or singl*) NEAR/1 (blind* or mask*)) or "randomi* control* trial*" or (random* NEAR/1 allocat*) or placebo*) 1,155,932 3 #2 AND #1 8 4 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 2,474,532 5 #3 NOT #4 7 Clarivate Analytics Web of Science SciELO Database name: SciELO Database platform: Clarivate Analytics Web of Science Dates of database coverage: 2002-present Date searched: 2023-02-27 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: N/A Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) or AB=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) 45 2 TS=((clinic* NEAR/1 trial*) or ((trebl* or tripl* or doubl* or singl*) NEAR/1 (blind* or mask*)) or "randomi* control* trial*" or (random* NEAR/1 allocat*) or placebo*) 9,265 3 #2 AND #1 0 Wiley Cochrane Central Register of Controlled Trials Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 02 of 12, October 2023 Date searched: 2023-02-27 Searched by: JF Number of results: 7 EndNote import order: 7 Number of results once duplicates removed: 2 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. ID Search Hits #1 MeSH descriptor: [Isosporiasis] this term only 2 #2 MeSH descriptor: [Isospora] this term only 2 #3 ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis):ti,ab,kw 7 #4 #1 or #2 or #3 7 WHO Global Index Medicus Database name: Global Index Medicus Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 2023-02-27 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: N/A ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) AND ("clinic* trial*" or "trebl* blind*" or "trebl* mask*" or "tripl* blind*" or "tripl* mask*" or "double* blind*" or "double* mask*" or "singl* blind*" or "singl* mask*" or "randomi* control* trial*" or "random allocat*" or "allocat* random" or placebo*) WHO International Clinical Trials Registry Platform Database name: International Clinical Trials Registry Platform Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 2023-02-27 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: All other search options cleared. Recruitment status: ALL Search conducted on Advanced Search page. Search terms entered into ‘Condition’ field. cystoisospora belli or isospora belli or cystoisosporiasis or isosporiasis ClinicalTrials.gov Database name: ClinicalTrials.gov Database platform: Clinicaltrials.gov Dates of database coverage: Complete database to search date Date searched: 2023-02-27 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes:Search run in ‘Condition’ field cystoisospora belli or isospora belli or cystoisosporiasis or isosporiasis Search 4: treatment SRs for relevant pathogens and eosinophilic meningitis For all searches the list of pathogens and resulting clinical conditions was agreed with the project team. The systematic reviews filter was derived from the filter published by CADTH.[3] Results from this search were deduplicated together with results from search 4a. OvidSP Medline ALL Database name: Medline ALL Database platform: OvidSP Dates of database coverage: 1946 to November 02, 2022 Date searched: 03 November 2022 Searched by: JF Number of results: 1241 EndNote import order: 1 (Medline) and 3 (Medline in process) Number of results once duplicates removed: 1093 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type SH: subject heading word TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp Schistosomiasis/ 24780 2 exp Schistosoma/ 18392 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 30315 4 exp Ancylostomatoidea/ 2723 5 exp Hookworm Infections/ 4365 6 exp Ascaris/ 5535 7 Ascariasis/ 5766 8 exp Strongyloides/ 2794 9 Strongyloidiasis/ 3979 10 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 19750 11 exp Larva Migrans/ 1620 12 exp Toxocara/ 2374 13 Toxocariasis/ 2047 14 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 5068 15 Wuchereria bancrofti/ 2384 16 Brugia/ or Brugia malayi/ 2174 17 filariasis/ or elephantiasis, filarial/ 8579 18 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 9898 19 exp echinococcosis/ 20484 20 exp Echinococcus/ 6320 21 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 21136 22 Paragonimiasis/ 1171 23 exp Paragonimus/ 948 24 (paragonimiasis or paragonimus or p westermani).ti,ab. 1851 25 coccidioidomycosis/ or paracoccidioidomycosis/ 5098 26 blastomyces/ or coccidioides/ or paracoccidioides/ 4063 27 Blastomycosis/ 2697 28 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 8584 29 exp Taenia/ 4383 30 cestode infections/ or exp taeniasis/ 11664 31 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 14835 32 hymenolepis/ or hymenolepis nana/ 1093 33 Hymenolepiasis/ 1108 34 (hymenolepi* or h nana).ti,ab. 2895 35 exp enoplida infections/ 7738 36 trichuroidea/ or Trichuris/ or exp trichinella/ 5601 37 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 4346 38 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 6416 39 Enterobius/ 972 40 Enterobiasis/ 793 41 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 2102 42 Anisakiasis/ 789 43 Anisakis/ 927 44 Ascaridoidea/ 862 45 Ascaridida Infections/ 558 46 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 1721 47 Angiostrongylus/ 679 48 Strongylida Infections/ 2621 49 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 1957 50 Meningitis/ and exp Eosinophilia/ 288 51 eosinophi* meningitis.ti,ab. 586 52 exp Fasciola/ 4505 53 Fascioliasis/ 4108 54 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 6284 55 exp Opisthorchidae/ 2008 56 clonorchiasis/ or opisthorchiasis/ 2594 57 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 5358 58 Gnathostomiasis/ 135 59 Gnathostoma/ 454 60 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 637 61 exp Onchocerca/ 2375 62 Onchocerciasis/ 3941 63 (onchocercias* or onchocerca or o volvulus).ti,ab. 5281 64 Loiasis/ 638 65 Loa/ 544 66 (loias* or loa loa).ti,ab. 931 67 Trichinellosis/ 5057 68 exp Trichinella/ 3837 69 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 5183 70 (swimmer* itch or cercarial dermatitis).ti,ab. 280 71 Sarcocystis/ 1659 72 Sarcocystosis/ 1601 73 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 241 74 Sparganosis/ 507 75 Sparganum/ 254 76 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1010 77 Histoplasmosis/ or Histoplasma/ or (histoplasm* or h capsulatum).ti,ab. 9320 78 Talaromyces/ or Penicillium/ or (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 17122 79 or/1-78 [PATHOGENS] 186724 80 (systematic review or meta-analysis).pt. 289809 81 meta-analysis/ or systematic review/ or systematic reviews as topic/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic review (topic)"/ or exp technology assessment, biomedical/ or network meta-analysis/ 326648 82 ((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab,kf. 290158 83 ((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab,kf. 14504 84 ((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab,kf. 36243 85 (data synthes* or data extraction* or data abstraction*).ti,ab,kf. 37290 86 (handsearch* or hand search*).ti,ab,kf. 10752 87 (mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab,kf. 33536 88 (met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab,kf. 11566 89 (meta regression* or metaregression*).ti,ab,kf. 13321 90 (meta-analy* or metaanaly* or systematic review* or biomedical technology assessment* or bio-medical technology assessment*).mp,hw. 430945 91 (medline or cochrane or pubmed or medlars or embase or cinahl).ti,ab,hw. 313725 92 (cochrane or (health adj2 technology assessment) or evidence report).jw. 21013 93 (comparative adj3 (efficacy or effectiveness)).ti,ab,kf. 16641 94 (outcomes research or relative effectiveness).ti,ab,kf. 10843 95 ((indirect or indirect treatment or mixed-treatment or bayesian) adj3 comparison*).ti,ab,kf. 4114 96 (multi* adj3 treatment adj3 comparison*).ti,ab,kf. 284 97 (mixed adj3 treatment adj3 (meta-analy* or metaanaly*)).ti,ab,kf. 176 98 umbrella review*.ti,ab,kf. 1168 99 (multi* adj2 paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 13 100 (multiparamet* adj2 evidence adj2 synthesis).ti,ab,kf. 18 101 (multi-paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 11 102 or/80-101 634508 103 79 and 102 1559 104 exp animals/ not humans.sh. 5059688 105 103 not 104 1340 106 limit 105 to english language 1248 107 remove duplicates from 106 1241 108 limit 107 to medline 1025 109 106 not 108 223 OvidSP Embase Classic+Embase Database name: Embase Classic+Embase Database platform: OvidSP Dates of database coverage: 1947 to 2022 November 02 Date searched: 03 November 2022 Searched by: JF Number of results: 2605 EndNote import order: 2 Number of results once duplicates removed: 1642 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 exp schistosomiasis/ 29358 2 schistosoma/ or schistosoma haematobium/ or schistosoma japonicum/ or schistosoma mansoni/ 25254 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 35756 4 hookworm/ or exp ancylostoma/ or exp necator/ 6938 5 exp hookworm infection/ 5393 6 exp Ascaris/ or Ascaris lumbricoides/ 10754 7 ascariasis/ 6902 8 strongyloides/ or strongyloides stercoralis/ 5441 9 exp strongyloidiasis/ 5499 10 Loeffler pneumonia/ 5379 11 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 24668 12 exp larva migrans/ 2400 13 exp Toxocara/ 4349 14 toxocariasis/ 2927 15 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 6151 16 Wuchereria bancrofti/ 3447 17 brugia/ or brugia malayi/ or brugia timori/ 2770 18 filariasis/ 10177 19 Brugian filariasis/ 210 20 Bancroftian filariasis/ 226 21 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 12030 22 exp echinococcosis/ 25625 23 exp Echinococcus/ 10646 24 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 25983 25 paragonimiasis/ 1623 26 paragonimus/ or paragonimus westermani/ 1476 27 (paragonimiasis or paragonimus or p westermani).ti,ab. 2234 28 coccidioidomycosis/ 5625 29 South American blastomycosis/ 2595 30 exp Blastomyces/ 1231 31 exp Coccidioides/ 2950 32 paracoccidioides/ or paracoccidioides brasiliensis/ 2495 33 blastomycosis/ 4147 34 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 11081 35 taenia/ or taenia saginata/ or taenia solium/ 6038 36 cestodiasis/ or exp taeniasis/ 13372 37 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 17037 38 hymenolepis/ or hymenolepis nana/ 2117 39 hymenolepiasis/ 323 40 (hymenolepi* or h nana).ti,ab. 3397 41 trichuris/ or trichuris trichiura/ 4901 42 enoplid infection/ or trichinosis/ or trichuriasis/ 7736 43 trichinella/ or trichinella spiralis/ 5329 44 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 5503 45 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 7292 46 exp Enterobius/ 2721 47 enterobiasis/ 2405 48 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 2761 49 ascarid infection/ or anisakiasis/ 1236 50 anisakis/ 1516 51 Ascaridoidea/ 932 52 pseudoterranova decipiens/ 51 53 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 2244 54 angiostrongylus/ or angiostrongylus costaricensis/ 902 55 strongyle infection/ 717 56 angiostrongyliasis/ 660 57 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 2243 58 eosinophilic meningitis/ 186 59 eosinophi* meningitis.ti,ab. 688 60 exp Fasciola/ 6785 61 fascioliasis/ 4836 62 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 7164 63 exp opisthorchiidae/ 3049 64 clonorchiasis/ 1206 65 opisthorchiasis/ 1860 66 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 6052 67 gnathostomiasis/ 347 68 exp gnathostoma/ 243 69 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 730 70 onchocerca/ or onchocerca volvulus/ 3264 71 exp onchocerciasis/ 6247 72 (onchocercias* or onchocerca or o volvulus).ti,ab. 6151 73 loiasis/ 483 74 exp Loa/ 1166 75 (loias* or loa loa).ti,ab. 1252 76 trichinosis/ 5081 77 trichinella/ or trichinella spiralis/ 5329 78 cercarial dermatitis/ 87 79 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 6032 80 (swimmer* itch or cercarial dermatitis).ti,ab. 355 81 exp Sarcocystis/ 2029 82 sarcocystosis/ 441 83 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 273 84 sparganosis/ 417 85 sparganum/ 258 86 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1120 87 exp histoplasmosis/ 11098 88 exp Histoplasma/ 5760 89 (histoplasm* or h capsulatum).ti,ab. 11247 90 talaromyces/ or talaromyces marneffei/ 1189 91 Penicillium/ 12817 92 penicilliosis/ 343 93 (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 18270 94 or/1-93 239394 95 (systematic review or meta-analysis).pt. 0 96 meta-analysis/ or systematic review/ or systematic reviews as topic/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic review (topic)"/ or exp technology assessment, biomedical/ or network meta-analysis/ 567480 97 ((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab,kf. 355529 98 ((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab,kf. 17037 99 ((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab,kf. 51332 100 (data synthes* or data extraction* or data abstraction*).ti,ab,kf. 45609 101 (handsearch* or hand search*).ti,ab,kf. 13098 102 (mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab,kf. 44463 103 (met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab,kf. 18670 104 (meta regression* or metaregression*).ti,ab,kf. 16375 105 (meta-analy* or metaanaly* or systematic review* or biomedical technology assessment* or bio-medical technology assessment*).mp,hw. 676551 106 (medline or cochrane or pubmed or medlars or embase or cinahl).ti,ab,hw. 408781 107 (cochrane or (health adj2 technology assessment) or evidence report).jw. 29446 108 (comparative adj3 (efficacy or effectiveness)).ti,ab,kf. 24671 109 (outcomes research or relative effectiveness).ti,ab,kf. 15911 110 ((indirect or indirect treatment or mixed-treatment or bayesian) adj3 comparison*).ti,ab,kf. 7099 111 (meta-analysis or systematic review).md. 0 112 (multi* adj3 treatment adj3 comparison*).ti,ab,kf. 410 113 (mixed adj3 treatment adj3 (meta-analy* or metaanaly*)).ti,ab,kf. 256 114 umbrella review*.ti,ab,kf. 1232 115 (multi* adj2 paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 27 116 (multiparamet* adj2 evidence adj2 synthesis).ti,ab,kf. 19 117 (multi-paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 22 118 or/95-117 914934 119 94 and 118 2855 120 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1172890 121 Animal experiment/ not (human experiment/ or human/) 2465523 122 120 or 121 2528018 123 119 not 122 2793 124 limit 123 to english language 2650 125 remove duplicates from 124 2605 OvidSP Global Health Database name: Global Health Database platform: OvidSP Dates of database coverage: 1910 to 2022 Week 43 Date searched: 03 November 2022 Searched by: JF Number of results: 846 EndNote import order: 4 Number of results once duplicates removed: 137 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Resuls 1 exp schistosomiasis/ 48521 2 schistosoma/ or schistosoma haematobium/ or schistosoma japonicum/ or schistosoma mansoni/ 52240 3 (Schistosomiasis or Schistosoma or Katayama syndrome or schistosomula or bilharzia or s mansoni or s japonicum or s haematobium).ti,ab. 49140 4 hookworms/ 11096 5 ascaris/ or ascaris lumbricoides/ 17663 6 ascariasis/ 6748 7 strongyloides/ or strongyloides stercoralis/ 8709 8 strongyloidiasis/ 6183 9 (hookworm or hook-worm or ancylostomatoid* or ancylostoma or a duodenale or necator or n americanus or ascaris or ascariasis or a lumbricoides or strongyloides or strongyloidiasis or loeffler? or larva currens or s stercoralis).ti,ab. 34851 10 larva migrans/ 1687 11 toxocara/ or toxocara canis/ or toxocara cati/ 6852 12 toxocariasis/ 2776 13 (larva migrans or toxocariasis or toxocara or t canis or t catis or neurotoxocar*).ti,ab. 7485 14 exp wuchereria bancrofti/ 7829 15 brugia/ or brugia malayi/ or brugia timori/ 5413 16 filariasis/ or bancroftian filariasis/ or brugian filariasis/ 21593 17 elephantiasis/ 2050 18 (wuchereria bancrofti or wuchereriasis or brugia malayi or brugia timori or filariasis or elephantiasis).ti,ab. 16912 19 exp echinococcosis/ 14927 20 echinococcus/ or echinococcus granulosus/ or echinococcus multilocularis/ 20708 21 (hydatid or echinococcus or e granulosus or e multilocularis or echinococcosis).ti,ab. 19237 22 paragonimus/ or paragonimiasis/ or paragonimus westermani/ 4166 23 (paragonimiasis or paragonimus or p westermani).ti,ab. 4112 24 coccidioidomycosis/ 3177 25 paracoccidioidomycosis/ 1951 26 exp blastomyces/ 3877 27 exp coccidioides/ 4656 28 exp paracoccidioides/ 3503 29 blastomycosis/ 2138 30 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or c immitis or paracoccidioides or p braziliensis or (valley fever not rift valley fever) or paracoccidioidal granuloma? or blastomycosis or blastomyces).ti,ab. 10393 31 taenia/ or taenia saginata/ or taenia solium/ 16724 32 cestode infections/ or taeniasis/ 48095 33 (tapeworm* or tape-worm or taeniasis or taeniases or taenia or cestode or t saginata or t solium or neurocysticerc*).ti,ab. 18748 34 "hymenolepis (cestoda)"/ or hymenolepis nana/ 6818 35 (hymenolepi* or h nana).ti,ab. 7007 36 trichuris/ or trichuridae/ or trichuriasis/ 11885 37 trichinella/ or trichinella spiralis/ 12552 38 (whipworm or whip-worm or trichuris or trichocephalias* trichurias* or t trichiura).ti,ab. 10676 39 (trichinellos* or trichinellias* or trichinos* or trichinella or t spiralis).ti,ab. 12112 40 enterobius/ or enterobius vermicularis/ 5794 41 enterobiasis/ 2267 42 (pinworm or pin-worm or enterobius or enterobias* or e vermicularis).ti,ab. 5786 43 anisakiasis/ 1124 44 exp anisakis/ 1863 45 ascaridiosis/ 568 46 (anisakias* or anisakis or pseudoterranova decipiens).ti,ab. 1875 47 angiostrongylus/ or angiostrongylus costaricensis/ 2551 48 angiostrongyliasis/ 930 49 (angiostrongyl* or a costaricensis or rat lung worm).ti,ab. 2566 50 exp fasciola/ 8675 51 fascioliasis/ 6433 52 (fasciolias* or fasciola or "f hepatica" or "f giganta").ti,ab. 8358 53 opisthorchiidae/ or exp clonorchis/ or exp opisthorchis/ 6528 54 clonorchiasis/ 1872 55 opisthorchiasis/ 1862 56 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or liver fluke*).ti,ab. 8245 57 gnathostoma/ or gnathostoma spinigerum/ or gnathostomiasis/ 926 58 (gnathostomias* or gnathostoma or g spinigerum).ti,ab. 923 59 onchocerca/ or onchocerca volvulus/ 9543 60 onchocerciasis/ 7345 61 (onchocercias* or onchocerca or o volvulus).ti,ab. 9250 62 exp loa/ 2094 63 (loias* or loa loa).ti,ab. 1752 64 trichinosis/ 7934 65 trichinella/ or trichinella spiralis/ 12552 66 (trichinella or trichinellias* or trichinellos* or t spiralis).ti,ab. 10793 67 cercarial dermatitis/ 578 68 (swimmer* itch or cercarial dermatitis).ti,ab. 460 69 exp sarcocystis/ 1541 70 sarcocystosis/ 528 71 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis).ti,ab. 246 72 sparganosis/ 603 73 (sparganosis or sparginum or sparganoses or plerocercoid larvae or diphyllopothrium or spirometra or sparganum).ti,ab. 1268 74 exp histoplasmosis/ 5351 75 histoplasma/ or histoplasma capsulatum/ 8510 76 (histoplasm* or h capsulatum).ti,ab. 9196 77 talaromyces/ or talaromyces marneffei/ 1149 78 (talaromyc* or t marneffei or penicillium or penicilliosis or p marneffei).ti,ab. 12358 79 exp eosinophilia/ and meningitis/ 155 80 eosinophi* meningitis.ti,ab. 582 81 or/1-80 225899 82 systematic reviews/ or meta-analysis/ 69314 83 ((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab. 56372 84 ((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab. 2499 85 ((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab. 7660 86 (data synthes* or data extraction* or data abstraction*).ti,ab. 6800 87 (handsearch* or hand search*).ti,ab. 1457 88 (mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab. 8203 89 (met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab. 1047 90 (meta regression* or metaregression*).ti,ab. 3641 91 (cochrane or (health adj2 technology assessment) or evidence report).jx. 954 92 (comparative adj3 (efficacy or effectiveness)).ti,ab. 2416 93 (outcomes research or relative effectiveness).ti,ab. 1172 94 ((indirect or indirect treatment or mixed-treatment or bayesian) adj3 comparison*).ti,ab. 452 95 (multi* adj3 treatment adj3 comparison*).ti,ab. 29 96 (mixed adj3 treatment adj3 (meta-analy* or metaanaly*)).ti,ab. 19 97 umbrella review*.ti,ab. 307 98 (multi* adj2 paramet* adj2 evidence adj2 synthesis).ti,ab. 7 99 (multiparamet* adj2 evidence adj2 synthesis).ti,ab. 6 100 (multi-paramet* adj2 evidence adj2 synthesis).ti,ab. 7 101 or/82-100 95544 102 81 and 101 1063 103 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 553943 104 102 not 103 970 105 limit 104 to english language 854 106 remove duplicates from 105 846 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 03 November 2022 Searched by: JF Number of results: 190 EndNote import order: 5 Number of results once duplicates removed: 20 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract MH: thesaurus terms TI: title TW: textword Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. # Query Results S1 (MH "Schistosomiasis") 1,226 S2 (TI (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) or (AB (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) 1,384 S3 (MH "Hookworm Infections") OR (MH "Strongylida Infections") 353 S4 (TI (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) or (AB (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) 1,320 S5 (MH "Larva Migrans") 114 S6 (MH "Toxocariasis") OR (MH "Ascariasis") OR (MH "Ascaridida Infections") 495 S7 (TI ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) or (AB ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) 351 S8 (MH "Elephantiasis, Filarial") OR (MH "Filariasis") 633 S9 (TI ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) or (AB ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) 666 S10 (MH "Echinococcosis+") 1,553 S11 (TI (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) or (AB (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) 1,767 S12 (MH "Paragonimiasis") 51 S13 (TI (paragonimiasis or paragonimus or "p westermani" )) or (AB (paragonimiasis or paragonimus or "p westermani" )) 77 S14 (MH "Coccidioidomycosis") 466 S15 (MH "Blastomycosis") 191 S16 (TI (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) or (AB (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) 859 S17 (MH "Taeniasis") 98 S18 (TI (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) or (AB (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) 968 S19 (MH "Cestode Infections") 73 S20 (TI (hymenolepi* or "h nana")) or (AB (hymenolepi* or "h nana")) 76 S21 (MH "Enoplida Infections+") 189 S22 (TI (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) or (AB (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) 233 S23 (TI (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) or (AB (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) 125 S24 (MH "Enterobiasis") 129 S25 (TI (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) or (AB (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) 192 S26 (MH "Ascaridida Infections") OR (MH "Ascariasis") 356 S27 (TI (anisakias* or anisakis or "pseudoterranova decipiens")) or (AB (anisakias* or anisakis or "pseudoterranova decipiens")) 96 S28 (MH "Strongylida Infections") 130 S29 (TI (angiostrongyl* or "a costaricensis" or "rat lung worm")) or (AB (angiostrongyl* or "a costaricensis" or "rat lung worm")) 82 S30 (MH "Fascioliasis") 126 S31 (TI (fasciolias* or fasciola or "f hepatica" or "f giganta")) or (AB (fasciolias* or fasciola or "f hepatica" or "f giganta")) 141 S32 (MH "Clonorchiasis") OR (MH "Opisthorchiasis") 54 S33 (TI (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) or (AB (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) 153 S34 (TI (gnathostomias* or gnathostoma or "g spinigerum")) or (AB (gnathostomias* or gnathostoma or "g spinigerum")) 47 S35 (MH "Onchocerciasis+") 249 S36 (TI (onchocercias* or onchocerca or "o volvulus")) or (AB (onchocercias* or onchocerca or "o volvulus")) 332 S37 (TI (loias* or "loa loa")) or (AB (loias* or "loa loa")) 90 S38 (TI (trichinella or trichinellias* or trichinellos* or "t spiralis")) or (AB (trichinella or trichinellias* or trichinellos* or "t spiralis")) 94 S39 (TI ("swimmer* itch" or "cercarial dermatitis")) or (AB ("swimmer* itch" or "cercarial dermatitis")) 22 S40 (TI (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) or (AB (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) 17 S41 (MH "Sparganosis") 44 S42 (TI (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) or (AB (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) 60 S43 (MH "Histoplasmosis") 710 S44 (TI (histoplasm* or "h capsulatum")) or (AB (histoplasm* or "h capsulatum")) 812 S45 (TI (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) or (AB (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) 573 S46 (MH "Eosinophilia+") 3,669 S47 (MH "Meningitis") 3,373 S48 S46 AND S47 37 S49 (TI "eosinophi* meningitis") OR (AB "eosinophi* meningitis") 64 S50 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 OR S27 OR S28 OR S29 OR S30 OR S31 OR S32 OR S33 OR S34 OR S35 OR S36 OR S37 OR S38 OR S39 OR S40 OR S41 OR S42 OR S43 OR S44 OR S45 OR S48 OR S49 10,796 S51 (MH "meta analysis" OR MH "systematic review" OR MH "Technology, Medical/EV" OR PT "systematic review" OR PT "meta analysis" OR MW meta-analy* OR MW metaanaly* OR MW "systematic review*" OR MW "biomedical technology assessment*" OR MW "bio-medical technology assessment*" OR ((TI systematic* OR AB systematic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI methodologic* OR AB methodologic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI quantitative OR AB quantitative) N3 (TI review* OR AB review* OR TI overview* OR AB overview* OR TI synthes* OR AB synthes*)) OR ((TI research OR AB research) N3 (TI integrati* OR AB integrati* OR TI overview* OR AB overview*)) OR ((TI integrative OR AB integrative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI collaborative OR AB collaborative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI pool* OR AB pool*) N3 (TI analy* OR AB analy*)) OR TI "data synthes*" OR AB "data synthes*" OR TI "data extraction*" OR AB "data extraction*" OR TI "data abstraction*" OR AB "data abstraction*" OR TI handsearch* OR AB handsearch* OR TI "hand search*" OR AB "hand search*" OR TI "mantel haenszel" OR AB "mantel haenszel" OR TI peto OR AB peto OR TI "der simonian" OR AB "der simonian" OR TI dersimonian OR AB dersimonian OR TI "fixed effect*" OR AB "fixed effect*" OR TI "latin square*" OR AB "latin square*" OR TI "met analy*" OR AB "met analy*" OR TI metanaly* OR AB metanaly* OR TI "technology assessment*" OR AB "technology assessment*" OR TI HTA OR AB HTA OR TI HTAs OR AB HTAs OR TI "technology overview*" OR AB "technology overview*" OR TI "technology appraisal*" OR AB "technology appraisal*" OR TI "meta regression*" OR AB "meta regression*" OR TI metaregression* OR AB metaregression* OR ((TI comparative OR AB comparative) N3 (TI efficacy OR AB efficacy OR TI effectiveness OR AB effectiveness)) OR TI "outcomes research" OR AB "outcomes research" OR TI "relative effectiveness" OR AB "relative effectiveness" OR ((TI indirect OR AB indirect OR TI "indirect treatment" OR AB "indirect treatment" OR TI mixed-treatment OR AB mixed-treatment OR TI bayesian OR AB bayesian) N3 (TI comparison* OR AB comparison*)) OR ((TI multi* OR AB multi*) N3 (TI treatment OR AB treatment) N3 (TI comparison* OR AB comparison*)) OR ((TI mixed OR AB mixed) N3 (TI treatment OR AB treatment) N3 (TI meta-analy* OR AB meta-analy* OR TI metaanaly* OR AB metaanaly*)) OR TI "umbrella review*" OR AB "umbrella review*" OR ((TI multi* OR AB multi*) N2 (TI paramet* OR AB paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multiparamet* OR AB multiparamet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multi-paramet* OR AB multi-paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis))) 253,878 S52 S50 AND S51 203 S53 (MH "Animals+") 104,766 S54 (MH "Animal Studies") 149,744 S55 (TI "animal model*") 3,464 S56 S53 OR S54 OR S55 245,576 S57 (MH human) 2,619,789 S58 S56 not S57 211,812 S59 S52 NOT S58 190 S60 S59 Limiters - English Language 190 EBSCOhost Africa-Wide Information Database name: Africa-Wide Information Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 03 November 2022 Searched by: JF Number of results: 367 EndNote import order: 6 Number of results once duplicates removed: 34 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TX: textword * is used for truncation of words. Nn finds words within n words of each other, in any order. # Query Results S1 (TI (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) or (AB (Schistosomiasis or Schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium")) 23,600 S2 (TI (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) or (AB (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis")) 6,843 S3 (TI ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) or (AB ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*)) 1,536 S4 (TI ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) or (AB ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis)) 12,027 S5 (TI (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) or (AB (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis)) 3,654 S6 (TI (paragonimiasis or paragonimus or "p westermani" )) or (AB (paragonimiasis or paragonimus or "p westermani" )) 518 S7 (TI (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) or (AB (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or blastomycosis or blastomyces)) 669 S8 (TI (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) or (AB (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*)) 7,403 S9 (TI (hymenolepi* or "h nana")) or (AB (hymenolepi* or "h nana")) 1,671 S10 (TI (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) or (AB (whipworm or "whip-worm" or trichuris or trichocephalias* trichurias* or "t trichiura")) 2,522 S11 (TI (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) or (AB (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis")) 1,235 S12 (TI (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) or (AB (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis")) 584 S13 (TI (anisakias* or anisakis or "pseudoterranova decipiens")) or (AB (anisakias* or anisakis or "pseudoterranova decipiens")) 343 S14 (TI (angiostrongyl* or "a costaricensis" or "rat lung worm")) or (AB (angiostrongyl* or "a costaricensis" or "rat lung worm")) 369 S15 (TI (fasciolias* or fasciola or "f hepatica" or "f giganta")) or (AB (fasciolias* or fasciola or "f hepatica" or "f giganta")) 1,947 S16 (TI (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) or (AB (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or "liver fluke*")) 1,137 S17 (TI (gnathostomias* or gnathostoma or "g spinigerum")) or (AB (gnathostomias* or gnathostoma or "g spinigerum")) 138 S18 (TI (onchocercias* or onchocerca or "o volvulus")) or (AB (onchocercias* or onchocerca or "o volvulus")) 5,950 S19 (TI (loias* or "loa loa")) or (AB (loias* or "loa loa")) 927 S20 (TI (trichinella or trichinellias* or trichinellos* or "t spiralis")) or (AB (trichinella or trichinellias* or trichinellos* or "t spiralis")) 1,120 S21 (TI ("swimmer* itch" or "cercarial dermatitis")) or (AB ("swimmer* itch" or "cercarial dermatitis")) 100 S22 (TI (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) or (AB (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis)) 131 S23 (TI (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) or (AB (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum)) 373 S24 (TI (histoplasm* or "h capsulatum")) or (AB (histoplasm* or "h capsulatum")) 1,071 S25 (TI (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) or (AB (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei")) 1,549 S26 (TI "eosinophi* meningitis") OR (AB "eosinophi* meningitis") 99 S27 S1 OR S2 OR S3 OR S4 OR S5 OR S6 OR S7 OR S8 OR S9 OR S10 OR S11 OR S12 OR S13 OR S14 OR S15 OR S16 OR S17 OR S18 OR S19 OR S20 OR S21 OR S22 OR S23 OR S24 OR S25 OR S26 63,878 S28 (((TI systematic* OR AB systematic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI methodologic* OR AB methodologic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI quantitative OR AB quantitative) N3 (TI review* OR AB review* OR TI overview* OR AB overview* OR TI synthes* OR AB synthes*)) OR ((TI research OR AB research) N3 (TI integrati* OR AB integrati* OR TI overview* OR AB overview*)) OR ((TI integrative OR AB integrative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI collaborative OR AB collaborative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI pool* OR AB pool*) N3 (TI analy* OR AB analy*)) OR TI "data synthes*" OR AB "data synthes*" OR TI "data extraction*" OR AB "data extraction*" OR TI "data abstraction*" OR AB "data abstraction*" OR TI handsearch* OR AB handsearch* OR TI "hand search*" OR AB "hand search*" OR TI "mantel haenszel" OR AB "mantel haenszel" OR TI peto OR AB peto OR TI "der simonian" OR AB "der simonian" OR TI dersimonian OR AB dersimonian OR TI "fixed effect*" OR AB "fixed effect*" OR TI "latin square*" OR AB "latin square*" OR TI "met analy*" OR AB "met analy*" OR TI metanaly* OR AB metanaly* OR TI "technology assessment*" OR AB "technology assessment*" OR TI HTA OR AB HTA OR TI HTAs OR AB HTAs OR TI "technology overview*" OR AB "technology overview*" OR TI "technology appraisal*" OR AB "technology appraisal*" OR TI "meta regression*" OR AB "meta regression*" OR TI metaregression* OR AB metaregression* OR ((TI comparative OR AB comparative) N3 (TI efficacy OR AB efficacy OR TI effectiveness OR AB effectiveness)) OR TI "outcomes research" OR AB "outcomes research" OR TI "relative effectiveness" OR AB "relative effectiveness" OR ((TI indirect OR AB indirect OR TI "indirect treatment" OR AB "indirect treatment" OR TI mixed-treatment OR AB mixed-treatment OR TI bayesian OR AB bayesian) N3 (TI comparison* OR AB comparison*)) OR ((TI multi* OR AB multi*) N3 (TI treatment OR AB treatment) N3 (TI comparison* OR AB comparison*)) OR ((TI mixed OR AB mixed) N3 (TI treatment OR AB treatment) N3 (TI meta-analy* OR AB meta-analy* OR TI metaanaly* OR AB metaanaly*)) OR TI "umbrella review*" OR AB "umbrella review*" OR ((TI multi* OR AB multi*) N2 (TI paramet* OR AB paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multiparamet* OR AB multiparamet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multi-paramet* OR AB multi-paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis))) 18,049 S29 S27 AND S28 401 S30 (TI (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*)) 86,704 S31 (TX (man or human)) 679,884 S32 S30 NOT S31 73,417 S33 S29 NOT S32 386 S34 S33 Limiters - Language: English 367 Clarivate Analytics Web of Science, Science Citation Index Database name: Science Citation Index-Expanded Database platform: Clarivate Analytics Web of Science Dates of database coverage: 1970-present Date searched: 03 November 2022 Searched by: JF Number of results: 948 EndNote import order: 7 Number of results once duplicates removed: 79 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") or AB=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") 22145 2 TI=("histoplasm*" or "h capsulatum") or AB=("histoplasm*" or "h capsulatum") 5582 3 TI=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") or AB=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") 754 4 TI=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") or AB=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") 163 5 TI=("swimmer* itch" or "cercarial dermatitis") or AB=("swimmer* itch" or "cercarial dermatitis") 200 6 TI=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") or AB=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") 4111 7 TI=("loias*" or "loa loa") or AB=("loias*" or "loa loa") 756 8 TI=("onchocercias*" or "onchocerca" or "o volvulus") or AB=("onchocercias*" or "onchocerca" or "o volvulus") 4685 9 TI=("gnathostomias*" or "gnathostoma" or "g spinigerum") or AB=("gnathostomias*" or "gnathostoma" or "g spinigerum") 437 10 TI=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") or AB=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") 3764 11 TI=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") or AB=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") 5424 12 TI=("angiostrongyl*" or "a costaricensis" or "rat lung worm") or AB=("angiostrongyl*" or "a costaricensis" or "rat lung worm") 1641 13 TI=("anisakias*" or "anisakis" or "pseudoterranova decipiens") or AB=("anisakias*" or "anisakis" or "pseudoterranova decipiens") 1923 14 TI=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") or AB=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") 1179 15 TI=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") or AB=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") 4517 16 TI=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") or AB=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") 3535 17 TI=("hymenolepi*" or "h nana") or AB=("hymenolepi*" or "h nana") 2261 18 TI=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") or AB=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") 12899 19 TI=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") or AB=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") 6819 20 TI=("paragonimiasis" or "paragonimus" or "p westermani") or AB=("paragonimiasis" or "paragonimus" or "p westermani") 1028 21 TI=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") or AB=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") 13411 22 TI=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") or AB=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") 7216 23 TI=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") or AB=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") 4130 24 TI=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") or AB=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") 15173 25 TI= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") or AB= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") 23983 26 TI=("eosinophili* meningitis") OR AB=("eosinophili* meningitis") 446 27 #26 OR #25 OR #24 OR #23 OR #22 OR #21 OR #20 OR #19 OR #18 OR #17 OR #16 OR #15 OR #14 OR #13 OR #12 OR #11 OR #10 OR #9 OR #8 OR #7 OR #6 OR #5 OR #4 OR #3 OR #2 OR #1 129523 28 TI=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) OR AB=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) 525280 29 #28 AND #27 1026 30 TI=(rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset*) NOT TS=(man or human) 2383181 31 #29 NOT #30 964 32 #29 NOT #30 and English (Languages) 948 Clarivate Analytics Web of Science SciELO Database name: SciELO Database platform: Clarivate Analytics Web of Science Dates of database coverage: 2002-present Date searched: 03 November 2022 Searched by: JF Number of results: 26 EndNote import order: 8 Number of results once duplicates removed: 16 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") or AB=("talaromyc*" or "t marneffei" or "penicillium" or "penicilliosis" or "p marneffei") 687 2 TI=("histoplasm*" or "h capsulatum") or AB=("histoplasm*" or "h capsulatum") 285 3 TI=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") or AB=("sparganosis" or "sparginum" or "sparganoses" or "plerocercoid larvae" or "diphyllopothrium" or "spirometra" or "sparganum") 25 4 TI=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") or AB=("sarcosystis" or "sarcocystiasis" or "sarcosporidi*" or "sarcocysti" or "sarcosystosis") 3 5 TI=("swimmer* itch" or "cercarial dermatitis") or AB=("swimmer* itch" or "cercarial dermatitis") 1 6 TI=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") or AB=("trichinella" or "trichinellias*" or "trichinellos*" or "t spiralis") 57 7 TI=("loias*" or "loa loa") or AB=("loias*" or "loa loa") 9 8 TI=("onchocercias*" or "onchocerca" or "o volvulus") or AB=("onchocercias*" or "onchocerca" or "o volvulus") 45 9 TI=("gnathostomias*" or "gnathostoma" or "g spinigerum") or AB=("gnathostomias*" or "gnathostoma" or "g spinigerum") 23 10 TI=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") or AB=("clonorchiasis" or "clonorchis" or "opisthorchi*" or "opisthorchiasis" or "liver fluke*") 24 11 TI=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") or AB=("fasciolias*" or "fasciola" or "f hepatica" or "f giganta") 264 12 TI=("angiostrongyl*" or "a costaricensis" or "rat lung worm") or AB=("angiostrongyl*" or "a costaricensis" or "rat lung worm") 114 13 TI=("anisakias*" or "anisakis" or "pseudoterranova decipiens") or AB=("anisakias*" or "anisakis" or "pseudoterranova decipiens") 80 14 TI=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") or AB=("pinworm" or "pin-worm" or "enterobius" or "enterobias*" or "e vermicularis") 107 15 TI=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") or AB=("trichinellos*" or "trichinellias*" or "trichinos*" or "trichinella" or "t spiralis") 66 16 TI=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") or AB=("whipworm" or "whip-worm" or "trichuris" or "trichocephalias* trichurias*" or "t trichiura") 269 17 TI=("hymenolepi*" or "h nana") or AB=("hymenolepi*" or "h nana") 102 18 TI=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") or AB=("tapeworm*" or "tape-worm" or "taeniasis" or "taeniases" or "taenia" or "cestode" or "t saginata" or "t solium" or "neurocysticerc*") 507 19 TI=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") or AB=("coccidioidomycos*" or "paracoccidioidomycos*" or "coccidioides" or "c immitis" or "paracoccidioides" or "p braziliensis" or ("valley fever" not "rift valley fever") or "paracoccidioidal granuloma*" or "blastomycosis" or "blastomyces") 399 20 TI=("paragonimiasis" or "paragonimus" or "p westermani") or AB=("paragonimiasis" or "paragonimus" or "p westermani") 21 21 TI=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") or AB=("hydatid" or "echinococcus" or "e granulosus" or "e multilocularis" or "echinococcosis") 310 22 TI=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") or AB=("wuchereria bancrofti" or "wuchereriasis" or "brugia malayi" or "brugia timori" or "filariasis" or "elephantiasis") 106 23 TI=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") or AB=("larva migrans" or "toxocariasis" or "toxocara" or "t canis" or "t catis" or "neurotoxocar*") 355 24 TI=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") or AB=("hookworm" or "hook-worm" or "ancylostomatoid*" or "ancylostoma" or "a duodenale" or "necator" or "n americanus" or "ascaris" or "ascariasis" or "a lumbricoides" or "strongyloides" or "strongyloidiasis" or "loeffler*" or "larva currens" or "s stercoralis") 768 25 TI= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") or AB= ("schistosomiasis" or "schistosoma" or "Katayama syndrome" or "schistosomula" or "bilharzia" or "s mansoni" or "s japonicum" or "s haematobium") 872 26 TI=("eosinophili* meningitis") OR AB=("eosinophili* meningitis") 26 27 #26 OR #25 OR #24 OR #23 OR #22 OR #21 OR #20 OR #19 OR #18 OR #17 OR #16 OR #15 OR #14 OR #13 OR #12 OR #11 OR #10 OR #9 OR #8 OR #7 OR #6 OR #5 OR #4 OR #3 OR #2 OR #1 4675 28 TI=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) OR AB=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) 14382 29 #28 AND #27 26 Wiley Cochrane Database of Systematic Reviews Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 11 of 12, November 2022 Date searched: 03 November 2022 Searched by: JF Number of results: 28 EndNote import order: 10 Number of results once duplicates removed: 3 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. # Search terms Results #1 MeSH descriptor: [Schistosomiasis] explode all trees 359 #2 MeSH descriptor: [Schistosoma] explode all trees 155 #3 (schistosomiasis or schistosoma or "Katayama syndrome" or schistosomula or bilharzia or "s mansoni" or "s japonicum" or "s haematobium"):ti,ab,kw 726 #4 MeSH descriptor: [Ancylostomatoidea] explode all trees 52 #5 MeSH descriptor: [Hookworm Infections] explode all trees 182 #6 MeSH descriptor: [Ascaris] explode all trees 84 #7 MeSH descriptor: [Ascariasis] this term only 152 #8 MeSH descriptor: [Strongyloides] explode all trees 19 #9 MeSH descriptor: [Strongyloidiasis] this term only 41 #10 (hookworm or "hook-worm" or ancylostomatoid* or ancylostoma or "a duodenale" or necator or "n americanus" or ascaris or ascariasis or "a lumbricoides" or strongyloides or strongyloidiasis or loeffler* or "larva currens" or "s stercoralis"):ti,ab,kw 752 #11 MeSH descriptor: [Larva Migrans] explode all trees 4 #12 MeSH descriptor: [Toxocara] explode all trees 1 #13 MeSH descriptor: [Toxocariasis] this term only 4 #14 ("larva migrans" or toxocariasis or toxocara or "t canis" or "t catis" or neurotoxocar*):ti,ab,kw 32 #15 MeSH descriptor: [Wuchereria bancrofti] this term only 103 #16 MeSH descriptor: [Brugia] this term only 6 #17 MeSH descriptor: [Brugia malayi] this term only 11 #18 MeSH descriptor: [Filariasis] this term only 91 #19 MeSH descriptor: [Elephantiasis, Filarial] this term only 136 #20 ("wuchereria bancrofti" or wuchereriasis or "brugia malayi" or "brugia timori" or filariasis or elephantiasis):ti,ab,kw 417 #21 MeSH descriptor: [Echinococcosis] explode all trees 58 #22 MeSH descriptor: [Echinococcus] explode all trees 11 #23 (hydatid or echinococcus or "e granulosus" or "e multilocularis" or echinococcosis):ti,ab,kw 141 #24 MeSH descriptor: [Paragonimiasis] this term only 4 #25 MeSH descriptor: [Paragonimus] explode all trees 1 #26 (paragonimiasis or paragonimus or "p westermani"):ti,ab,kw 6 #27 MeSH descriptor: [Coccidioidomycosis] this term only 17 #28 MeSH descriptor: [Paracoccidioidomycosis] this term only 5 #29 MeSH descriptor: [Blastomyces] this term only 0 #30 MeSH descriptor: [Coccidioides] this term only 4 #31 MeSH descriptor: [Paracoccidioides] this term only 0 #32 MeSH descriptor: [Blastomycosis] this term only 5 #33 (coccidioidomycos* or paracoccidioidomycos* or coccidioides or "c immitis" or paracoccidioides or "p braziliensis" or ("valley fever" not "rift valley fever") or (paracoccidioidal NEXT granuloma*) or blastomycosis or blastomyces):ti,ab,kw 61 #34 MeSH descriptor: [Taenia] explode all trees 24 #35 MeSH descriptor: [Cestode Infections] this term only 1 #36 MeSH descriptor: [Taeniasis] explode all trees 82 #37 (tapeworm* or "tape-worm" or taeniasis or taeniases or taenia or cestode or "t saginata" or "t solium" or neurocysticerc*):ti,ab,kw 181 #38 MeSH descriptor: [Hymenolepis] this term only 1 #39 MeSH descriptor: [Hymenolepis nana] this term only 2 #40 MeSH descriptor: [Hymenolepiasis] this term only 5 #41 (hymenolepi* or "h nana"):ti,ab,kw 24 #42 MeSH descriptor: [Enoplida Infections] explode all trees 150 #43 MeSH descriptor: [Trichuroidea] this term only 2 #44 MeSH descriptor: [Trichuris] this term only 69 #45 MeSH descriptor: [Trichinella] explode all trees 2 #46 (whipworm or "whip-worm" or trichuris or (trichocephalias* NEXT trichurias*) or "t trichiura"):ti,ab,kw 372 #47 (trichinellos* or trichinellias* or trichinos* or trichinella or "t spiralis"):ti,ab,kw 11 #48 MeSH descriptor: [Enterobius] this term only 15 #49 MeSH descriptor: [Enterobiasis] this term only 9 #50 (pinworm or "pin-worm" or enterobius or enterobias* or "e vermicularis"):ti,ab,kw 55 #51 MeSH descriptor: [Anisakiasis] this term only 2 #52 MeSH descriptor: [Anisakis] this term only 3 #53 MeSH descriptor: [Ascaridoidea] this term only 0 #54 MeSH descriptor: [Ascaridida Infections] this term only 0 #55 (anisakias* or anisakis or "pseudoterranova decipiens"):ti,ab,kw 7 #56 MeSH descriptor: [Angiostrongylus] this term only 0 #57 MeSH descriptor: [Strongylida Infections] this term only 2 #58 (angiostrongyl* or "a costaricensis" or "rat lung worm"):ti,ab,kw 5 #59 MeSH descriptor: [Fasciola] explode all trees 6 #60 MeSH descriptor: [Fascioliasis] this term only 11 #61 (fasciolias* or fasciola or "f hepatica" or "f giganta"):ti,ab,kw 28 #62 MeSH descriptor: [Opisthorchidae] explode all trees 18 #63 MeSH descriptor: [Clonorchiasis] this term only 11 #64 MeSH descriptor: [Opisthorchiasis] this term only 19 #65 (clonorchiasis or clonorchis or opisthorchi* or opisthorchiasis or (liver NEXT fluke*)):ti,ab,kw 63 #66 MeSH descriptor: [Gnathostomiasis] this term only 0 #67 MeSH descriptor: [Gnathostoma] this term only 7 #68 (gnathostomias* or gnathostoma or "g spinigerum"):ti,ab,kw 10 #69 MeSH descriptor: [Onchocerca] explode all trees 75 #70 MeSH descriptor: [Onchocerciasis] this term only 148 #71 (onchocercias* or onchocerca or "o volvulus"):ti,ab,kw 284 #72 MeSH descriptor: [Loiasis] this term only 14 #73 MeSH descriptor: [Loa] this term only 7 #74 (loias* or "loa loa"):ti,ab,kw 44 #75 MeSH descriptor: [Trichinellosis] this term only 6 #76 MeSH descriptor: [Trichinella] explode all trees 2 #77 (trichinella or trichinellias* or trichinellos* or "t spiralis"):ti,ab,kw 8 #78 ((swimmer* NEXT itch) or "cercarial dermatitis"):ti,ab,kw 1 #79 MeSH descriptor: [Sarcocystis] this term only 0 #80 MeSH descriptor: [Sarcocystosis] this term only 0 #81 (sarcosystis or sarcocystiasis or sarcosporidi* or sarcocysti or sarcosystosis):ti,ab,kw 0 #82 MeSH descriptor: [Sparganosis] this term only 0 #83 MeSH descriptor: [Sparganum] this term only 0 #84 (sparganosis or sparginum or sparganoses or "plerocercoid larvae" or diphyllopothrium or spirometra or sparganum):ti,ab,kw 1 #85 MeSH descriptor: [Histoplasmosis] this term only 48 #86 MeSH descriptor: [Histoplasma] this term only 1 #87 (histoplasm* or "h capsulatum"):ti,ab,kw 129 #88 MeSH descriptor: [Talaromyces] this term only 3 #89 MeSH descriptor: [Penicillium] this term only 5 #90 (talaromyc* or "t marneffei" or penicillium or penicilliosis or "p marneffei"):ti,ab,kw 52 #91 MeSH descriptor: [Meningitis] this term only 309 #92 MeSH descriptor: [Eosinophilia] explode all trees 449 #93 #91 AND #92 4 #94 (eosinophili* NEXT meningitis):ti,ab,kw 5 #95 {OR #1-#90} OR #93 OR #94 2781 WHO Global Index Medicus Database name: Global Index Medicus Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 03 November 2022 Searched by: JF Number of results: 55 EndNote import order: 9 Number of results once duplicates removed: 9 Search strategy notes: N/A tw:((schistosomiasis OR schistosoma OR "Katayama syndrome" OR schistosomula OR bilharzia OR "s mansoni" OR "s japonicum" OR "s haematobium" OR hookworm OR "hook-worm" OR ancylostomatoid* OR ancylostoma OR "a duodenale" OR necator OR "n americanus" OR ascaris OR ascariasis OR "a lumbricoides" OR strongyloides OR strongyloidiasis OR loeffler* OR "larva currens" OR "s stercoralis" OR "larva migrans" OR toxocariasis OR toxocara OR "t canis" OR "t catis" OR neurotoxocar* OR "wuchereria bancrofti" OR wuchereriasis OR "brugia malayi" OR "brugia timori" OR filariasis OR elephantiasis OR hydatid OR echinococcus OR "e granulosus" OR "e multilocularis" OR echinococcosis OR paragonimiasis OR paragonimus OR "p westermani" OR coccidioidomycos* OR paracoccidioidomycos* OR coccidioides OR "c immitis" OR paracoccidioides OR "p braziliensis" OR ("valley fever" not "rift valley fever") OR "paracoccidioidal granuloma*" OR blastomycosis OR blastomyces OR tapeworm* OR "tape-worm" OR taeniasis OR taeniases OR taenia OR cestode OR "t saginata" OR "t solium" OR neurocysticerc* OR hymenolepi* OR "h nana" OR whipworm OR "whip-worm" OR trichuris OR trichocephalias* trichurias* OR "t trichiura" OR trichinellos* OR trichinellias* OR trichinos* OR trichinella OR "t spiralis" OR pinworm OR "pin-worm" OR enterobius OR enterobias* OR "e vermicularis" OR anisakias* OR anisakis OR "pseudoterranova decipiens" OR angiostrongyl* OR "a costaricensis" OR "rat lung worm" OR fasciolias* OR fasciola OR "f hepatica" OR "f giganta" OR clonorchiasis OR clonorchis OR opisthorchi* OR opisthorchiasis OR "liver fluke*" OR gnathostomias* OR gnathostoma OR "g spinigerum" OR onchocercias* OR onchocerca OR "o volvulus" OR loias* OR "loa loa" OR trichinella OR trichinellias* OR trichinellos* OR "t spiralis" OR "swimmer* itch" OR "cercarial dermatitis" OR sarcosystis OR sarcocystiasis OR sarcosporidi* OR sarcocysti OR sarcosystosis OR sparganosis OR sparginum OR sparganoses OR "plerocercoid larvae" OR diphyllopothrium OR spirometra OR sparganum OR histoplasm* OR "h capsulatum" OR talaromyc* OR "t marneffei" OR penicillium OR penicilliosis OR "p marneffei" OR (eosinophil* AND meningitis))) AND ( type_of_study:("systematic_reviews" OR "policy_brief" OR "sysrev_observational_studies" OR "health_technology_assessment") AND la:("en")) Search 4a: treatment SRs for cystoisospora The systematic reviews filter was derived from the filter published by CADTH.[3] Results from this search were deduplicated together with results from search 4. OvidSP Medline ALL Database name: Medline ALL Database platform: OvidSP Dates of database coverage: 1946 to March 27, 2023 Date searched: 2023-03-28 Searched by: JF Number of results: 4 EndNote import order: 1 Number of results once duplicates removed: 3 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type SH: subject heading word TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 (systematic review or meta-analysis).pt. 305745 2 meta-analysis/ or systematic review/ or systematic reviews as topic/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic review (topic)"/ or exp technology assessment, biomedical/ or network meta-analysis/ 343539 3 ((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab,kf. 308953 4 ((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab,kf. 15226 5 ((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab,kf. 37912 6 (data synthes* or data extraction* or data abstraction*).ti,ab,kf. 39211 7 (handsearch* or hand search*).ti,ab,kf. 10997 8 (mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab,kf. 34878 9 (met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab,kf. 11923 10 (meta regression* or metaregression*).ti,ab,kf. 14114 11 (meta-analy* or metaanaly* or systematic review* or biomedical technology assessment* or bio-medical technology assessment*).mp,hw. 453782 12 (medline or cochrane or pubmed or medlars or embase or cinahl).ti,ab,hw. 331086 13 (cochrane or (health adj2 technology assessment) or evidence report).jw. 21307 14 (comparative adj3 (efficacy or effectiveness)).ti,ab,kf. 17214 15 (outcomes research or relative effectiveness).ti,ab,kf. 11095 16 ((indirect or indirect treatment or mixed-treatment or bayesian) adj3 comparison*).ti,ab,kf. 4261 17 (multi* adj3 treatment adj3 comparison*).ti,ab,kf. 290 18 (mixed adj3 treatment adj3 (meta-analy* or metaanaly*)).ti,ab,kf. 178 19 umbrella review*.ti,ab,kf. 1367 20 (multi* adj2 paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 14 21 (multiparamet* adj2 evidence adj2 synthesis).ti,ab,kf. 18 22 (multi-paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 12 23 or/1-22 664965 24 Isosporiasis/ or Isospora/ 853 25 (cystoisospora belli or isospora belli).ti,ab. 468 26 (cystoisosporiasis or isosporiasis).ti,ab. 158 27 or/24-26 1187 28 23 and 27 4 29 exp animals/ not humans.sh. 5106350 30 28 not 29 4 OvidSP Embase Classic+Embase Database name: Embase Classic+Embase Database platform: OvidSP Dates of database coverage: 1947 to 2023 march 28 Date searched: 2023-03-29 Searched by: JF Number of results: 17 EndNote import order: 2 Number of results once duplicates removed: 8 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 (systematic review or meta-analysis).pt. 0 2 meta-analysis/ or systematic review/ or systematic reviews as topic/ or meta-analysis as topic/ or "meta analysis (topic)"/ or "systematic review (topic)"/ or exp technology assessment, biomedical/ or network meta-analysis/ 626854 3 ((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab,kf. 394052 4 ((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab,kf. 18222 5 ((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab,kf. 55306 6 (data synthes* or data extraction* or data abstraction*).ti,ab,kf. 49740 7 (handsearch* or hand search*).ti,ab,kf. 13621 8 (mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab,kf. 47262 9 (met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab,kf. 20230 10 (meta regression* or metaregression*).ti,ab,kf. 18164 11 (meta-analy* or metaanaly* or systematic review* or biomedical technology assessment* or bio-medical technology assessment*).mp,hw. 739806 12 (medline or cochrane or pubmed or medlars or embase or cinahl).ti,ab,hw. 447591 13 (cochrane or (health adj2 technology assessment) or evidence report).jw. 31196 14 (comparative adj3 (efficacy or effectiveness)).ti,ab,kf. 26487 15 (outcomes research or relative effectiveness).ti,ab,kf. 16730 16 ((indirect or indirect treatment or mixed-treatment or bayesian) adj3 comparison*).ti,ab,kf. 7605 17 (meta-analysis or systematic review).md. 0 18 (multi* adj3 treatment adj3 comparison*).ti,ab,kf. 432 19 (mixed adj3 treatment adj3 (meta-analy* or metaanaly*)).ti,ab,kf. 258 20 umbrella review*.ti,ab,kf. 1526 21 (multi* adj2 paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 28 22 (multiparamet* adj2 evidence adj2 synthesis).ti,ab,kf. 21 23 (multi-paramet* adj2 evidence adj2 synthesis).ti,ab,kf. 23 24 or/1-23 990224 25 cystoisospora/ or isospora belli/ 572 26 isosporiasis/ 278 27 (cystoisospora belli or isospora belli).ti,ab. 549 28 (cystoisosporiasis or isosporiasis).ti,ab. 174 29 or/25-28 1050 30 24 and 29 18 31 (rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1).ti. and animal experiment/ 1218798 32 Animal experiment/ not (human experiment/ or human/) 2563365 33 31 or 32 2630853 34 30 not 33 19 35 limit 34 to english language 18 36 remove duplicates from 35 18 OvidSP Global Health Database name: Global Health Database platform: OvidSP Dates of database coverage: 1910 to 2023 week 12 Date searched: 2023-03-29 Searched by: JF Number of results: 1 EndNote import order: 3 Number of results once duplicates removed: 0 Search strategy notes: Search lines ending in a ‘/’ are subject heading searches. Search lines beginning ‘exp’ are exploded subject heading searches. Search lines beginning * are focused subject heading searches. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract PT: publication type TI: title TW: textword or/x-y combines search sets in the range x-y with Boolean operator OR. $ or * is used for truncation of words. adjn finds words within n words of each other, in any order. # Search terms Results 1 isospora/ or isospora belli/ 1780 2 isosporiasis/ 554 3 (cystoisospora belli or isospora belli).ti,ab. 652 4 (cystoisosporiasis or isosporiasis).ti,ab. 148 5 or/1-4 1864 6 systematic reviews/ or meta-analysis/ 73028 7 ((systematic* adj3 (review* or overview*)) or (methodologic* adj3 (review* or overview*))).ti,ab. 59607 8 ((quantitative adj3 (review* or overview* or synthes*)) or (research adj3 (integrati* or overview*))).ti,ab. 2631 9 ((integrative adj3 (review* or overview*)) or (collaborative adj3 (review* or overview*)) or (pool* adj3 analy*)).ti,ab. 8009 10 (data synthes* or data extraction* or data abstraction*).ti,ab. 7161 11 (handsearch* or hand search*).ti,ab. 1489 12 (mantel haenszel or peto or der simonian or dersimonian or fixed effect* or latin square*).ti,ab. 8483 13 (met analy* or metanaly* or technology assessment* or HTA or HTAs or technology overview* or technology appraisal*).ti,ab. 1088 14 (meta regression* or metaregression*).ti,ab. 3798 15 (cochrane or (health adj2 technology assessment) or evidence report).jx. 1048 16 (comparative adj3 (efficacy or effectiveness)).ti,ab. 2490 17 (outcomes research or relative effectiveness).ti,ab. 1210 18 ((indirect or indirect treatment or mixed-treatment or bayesian) adj3 comparison*).ti,ab. 468 19 (multi* adj3 treatment adj3 comparison*).ti,ab. 30 20 (mixed adj3 treatment adj3 (meta-analy* or metaanaly*)).ti,ab. 19 21 umbrella review*.ti,ab. 344 22 (multi* adj2 paramet* adj2 evidence adj2 synthesis).ti,ab. 7 23 (multiparamet* adj2 evidence adj2 synthesis).ti,ab. 6 24 (multi-paramet* adj2 evidence adj2 synthesis).ti,ab. 7 25 or/6-24 100220 26 5 and 25 1 27 ((rat or rats or mouse or mice or swine or porcine or murine or sheep or lambs or pigs or piglets or rabbit or rabbits or cat or cats or dog or dogs or cattle or bovine or monkey or monkeys or trout or marmoset$1) not man).sh. 562495 28 26 not 27 1 EBSCOhost CINAHL Complete Database name: CINAHL Complete Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 2023-03-29 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract MH: thesaurus terms TI: title TW: textword Thesaurus terms ending in + are exploded. * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (TI ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) or (AB ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) 50 S2 (MH "meta analysis" OR MH "systematic review" OR MH "Technology, Medical/EV" OR PT "systematic review" OR PT "meta analysis" OR MW meta-analy* OR MW metaanaly* OR MW "systematic review*" OR MW "biomedical technology assessment*" OR MW "bio-medical technology assessment*" OR ((TI systematic* OR AB systematic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI methodologic* OR AB methodologic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI quantitative OR AB quantitative) N3 (TI review* OR AB review* OR TI overview* OR AB overview* OR TI synthes* OR AB synthes*)) OR ((TI research OR AB research) N3 (TI integrati* OR AB integrati* OR TI overview* OR AB overview*)) OR ((TI integrative OR AB integrative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI collaborative OR AB collaborative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI pool* OR AB pool*) N3 (TI analy* OR AB analy*)) OR TI "data synthes*" OR AB "data synthes*" OR TI "data extraction*" OR AB "data extraction*" OR TI "data abstraction*" OR AB "data abstraction*" OR TI handsearch* OR AB handsearch* OR TI "hand search*" OR AB "hand search*" OR TI "mantel haenszel" OR AB "mantel haenszel" OR TI peto OR AB peto OR TI "der simonian" OR AB "der simonian" OR TI dersimonian OR AB dersimonian OR TI "fixed effect*" OR AB "fixed effect*" OR TI "latin square*" OR AB "latin square*" OR TI "met analy*" OR AB "met analy*" OR TI metanaly* OR AB metanaly* OR TI "technology assessment*" OR AB "technology assessment*" OR TI HTA OR AB HTA OR TI HTAs OR AB HTAs OR TI "technology overview*" OR AB "technology overview*" OR TI "technology appraisal*" OR AB "technology appraisal*" OR TI "meta regression*" OR AB "meta regression*" OR TI metaregression* OR AB metaregression* OR ((TI comparative OR AB comparative) N3 (TI efficacy OR AB efficacy OR TI effectiveness OR AB effectiveness)) OR TI "outcomes research" OR AB "outcomes research" OR TI "relative effectiveness" OR AB "relative effectiveness" OR ((TI indirect OR AB indirect OR TI "indirect treatment" OR AB "indirect treatment" OR TI mixed-treatment OR AB mixed-treatment OR TI bayesian OR AB bayesian) N3 (TI comparison* OR AB comparison*)) OR ((TI multi* OR AB multi*) N3 (TI treatment OR AB treatment) N3 (TI comparison* OR AB comparison*)) OR ((TI mixed OR AB mixed) N3 (TI treatment OR AB treatment) N3 (TI meta-analy* OR AB meta-analy* OR TI metaanaly* OR AB metaanaly*)) OR TI "umbrella review*" OR AB "umbrella review*" OR ((TI multi* OR AB multi*) N2 (TI paramet* OR AB paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multiparamet* OR AB multiparamet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multi-paramet* OR AB multi-paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis))) 264,263 S3 S1 AND S2 0 EBSCOhost Africa-Wide Information Database name: Africa-Wide Information Database platform: EBSCOhost Dates of database coverage: Complete database to search date Date searched: 2023-03-29 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TX: textword * is used for truncation of words. Nn finds words within n words of each other, in any order. # Search terms Results S1 (TI ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) or (AB ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis)) 184 S2 (MH "meta analysis" OR MH "systematic review" OR MH "Technology, Medical/EV" OR PT "systematic review" OR PT "meta analysis" OR MW meta-analy* OR MW metaanaly* OR MW "systematic review*" OR MW "biomedical technology assessment*" OR MW "bio-medical technology assessment*" OR ((TI systematic* OR AB systematic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI methodologic* OR AB methodologic*) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI quantitative OR AB quantitative) N3 (TI review* OR AB review* OR TI overview* OR AB overview* OR TI synthes* OR AB synthes*)) OR ((TI research OR AB research) N3 (TI integrati* OR AB integrati* OR TI overview* OR AB overview*)) OR ((TI integrative OR AB integrative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI collaborative OR AB collaborative) N3 (TI review* OR AB review* OR TI overview* OR AB overview*)) OR ((TI pool* OR AB pool*) N3 (TI analy* OR AB analy*)) OR TI "data synthes*" OR AB "data synthes*" OR TI "data extraction*" OR AB "data extraction*" OR TI "data abstraction*" OR AB "data abstraction*" OR TI handsearch* OR AB handsearch* OR TI "hand search*" OR AB "hand search*" OR TI "mantel haenszel" OR AB "mantel haenszel" OR TI peto OR AB peto OR TI "der simonian" OR AB "der simonian" OR TI dersimonian OR AB dersimonian OR TI "fixed effect*" OR AB "fixed effect*" OR TI "latin square*" OR AB "latin square*" OR TI "met analy*" OR AB "met analy*" OR TI metanaly* OR AB metanaly* OR TI "technology assessment*" OR AB "technology assessment*" OR TI HTA OR AB HTA OR TI HTAs OR AB HTAs OR TI "technology overview*" OR AB "technology overview*" OR TI "technology appraisal*" OR AB "technology appraisal*" OR TI "meta regression*" OR AB "meta regression*" OR TI metaregression* OR AB metaregression* OR ((TI comparative OR AB comparative) N3 (TI efficacy OR AB efficacy OR TI effectiveness OR AB effectiveness)) OR TI "outcomes research" OR AB "outcomes research" OR TI "relative effectiveness" OR AB "relative effectiveness" OR ((TI indirect OR AB indirect OR TI "indirect treatment" OR AB "indirect treatment" OR TI mixed-treatment OR AB mixed-treatment OR TI bayesian OR AB bayesian) N3 (TI comparison* OR AB comparison*)) OR ((TI multi* OR AB multi*) N3 (TI treatment OR AB treatment) N3 (TI comparison* OR AB comparison*)) OR ((TI mixed OR AB mixed) N3 (TI treatment OR AB treatment) N3 (TI meta-analy* OR AB meta-analy* OR TI metaanaly* OR AB metaanaly*)) OR TI "umbrella review*" OR AB "umbrella review*" OR ((TI multi* OR AB multi*) N2 (TI paramet* OR AB paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multiparamet* OR AB multiparamet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis)) OR ((TI multi-paramet* OR AB multi-paramet*) N2 (TI evidence OR AB evidence) N2 (TI synthesis OR AB synthesis))) 18,102 S3 S1 AND S2 0 Clarivate Analytics Web of Science, Science Citation Index Database name: Science Citation Index-Expanded Database platform: Clarivate Analytics Web of Science Dates of database coverage: 1970-present Date searched: 2023-03-29 Searched by: JF Number of results: 1 EndNote import order: 4 Number of results once duplicates removed: 0 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) or AB=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) 351 2 2TI=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) OR AB=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) 550957 3 #2 AND #1 1 Clarivate Analytics Web of Science SciELO Database name: SciELO Database platform: Clarivate Analytics Web of Science Dates of database coverage: 2002-present Date searched: 2023-03-29 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: Two-letter codes at the start of search lines designate the fields to search. Fields codes used are: AB: abstract TI: title TS: topic * is used for truncation of words. Nearn finds words within n words of each other, in any order. # Search terms Results 1 TI=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) or AB=("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis) 45 2 2TI=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) OR AB=((systematic* NEAR/3 (review* OR overview*)) OR (methodologic* NEAR/3 (review* OR overview*)) OR ("quantitative" NEAR/3 (review* OR overview* OR synthes*)) OR ("research" NEAR/3 (integrati* OR overview*)) OR ("integrative" NEAR/3 (review* OR overview*)) OR ("collaborative" NEAR/3 (review* OR overview*)) OR (pool* NEAR/3 analy*) OR "data synthes*" OR "data extraction*" OR "data abstraction*" OR handsearch* OR "hand search*" OR "mantel haenszel" OR "peto" OR "der simonian" OR "dersimonian" OR "fixed effect*" OR "latin square*" OR "met analy*" OR metanaly* OR "technology assessment*" OR "HTA" OR "HTAs" OR "technology overview*" OR "technology appraisal*" OR "meta regression*" OR metaregression* OR "meta-analy*" OR metaanaly* OR "biomedical technology assessment*" OR "bio-medical technology assessment*" OR ("comparative" NEAR/3 ("efficacy" OR "effectiveness")) OR "outcomes research" OR "relative effectiveness" OR (("indirect" OR "indirect treatment" OR "mixed-treatment" OR "bayesian") NEAR/3 comparison*) OR (multi* NEAR/3 "treatment" NEAR/3 comparison* ) OR ("mixed" NEAR/3 "treatment" NEAR/3 (meta-analy* OR metaanaly*)) OR "umbrella review*" OR (multi* NEAR/2 paramet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multiparamet* NEAR/2 "evidence" NEAR/2 "synthesis") OR (multi-paramet* NEAR/2 "evidence" NEAR/2 "synthesis")) 15,400 3 #2 AND #1 0 Wiley Cochrane Database of Systematic Reviews Database name: Cochrane Central Register of Controlled Trials Database platform: Wiley Cochrane Library Dates of database coverage: Issue 2 of 12, February 2023 Date searched: 2023-03-29 Searched by: JF Number of results: 0 EndNote import order: N/A Number of results once duplicates removed: 0 Search strategy notes: All databases in the Cochrane Library are searched simultaneously, therefore the search results below contain results from other Cochrane Library databases. Two-letter codes at the end of search lines designate the fields to search. Fields codes used are: AB: abstract KW: author keyword TI: title * is used for truncation of words. NEARn finds words within n words of each other, in any order. NEXT finds words next to each other in the order they are entered. # Search terms Results #1 MeSH descriptor: [Isosporiasis] this term only 2 #2 MeSH descriptor: [Isospora] this term only 2 #3 ("cystoisospora belli" or "isospora belli" or cystoisosporiasis or isosporiasis):ti,ab,kw 7 #4 #1 or #2 or #3 7 WHO Global Index Medicus Database name: Global Index Medicus Database platform: World Health Organization Dates of database coverage: Complete database to search date Date searched: 03 November 2022 Searched by: JF Number of results: 9 EndNote import order: 5 Number of results once duplicates removed: 9 Search strategy notes:N/A "cystoisospora belli" OR "isospora belli" OR cystoisosporiasis OR isosporiasis AND ( type_of_study:("guideline")) References 1. Buss I, Genton B, D’Acremont V. Aetiology of fever in returning travellers and migrants: a systematic review and meta-analysis. J Travel Med. 2020 27(8) taaa207. DOI: https://dx.doi.org/10.1093/jtm/taaa207. 2. Healthcare Improvement Scotland: SIGN. Search filters. [Internet] 2021. Available from: https://www.sign.ac.uk/what-we-do/methodology/search-filters/. 3. SR / MA / HTA / ITC - MEDLINE, Embase, PsycInfo. In: CADTH Search Filters Database. Ottawa: CADTH; 2022: https://searchfilters.cadth.ca/link/33. Accessed 2022-11-03. 4. Falconer J. Removing duplicates from an EndNote Library. Library & Archives Service Blog [Internet]: London School of Hygiene & Tropical Medicine. 2018. [cited 2020]. Available from: https://blogs.lshtm.ac.uk/library/2018/12/07/removing-duplicates-from-an-endnote-library/.