10.17037/DATA.00003850
This collection contains several datasets collected and analysed as part of the MORBID-FGS (Morbidity Operational Research for Bilharziasis Implementation Decisions for Girls and Women) cross sectional study. The aim of this study was to estimate the FGS burden by conventional and novel diagnostic methods in two S. haematobium endemic areas in Malawi. It also assessed the urinary, and sexual and reproductive health (SRH) symptoms associated with FGS. Work was conducted in Nsanje and Chikwawa, Malawi between November 2020 and May 2021. The datasets contain variables on socio-demographic characteristics of the study population, water contact information, and history of urinary, genital, and SRH signs and symptoms. In addition, the datasets also present variables for individual S. haematobium status, and FGS status using both visual and molecular diagnostic methods.
Due to the sensitive nature of the data collected in the MORBID-FGS study, anonymised data will be available by request. Data will be provided for use in research that has ethical approval, subject to the signing of a Data Sharing Agreement.
Sixty villages per district were randomly selected for the parent MORBID study, half from high and low prevalence areas, determined by epidemiological mapping reassessment surveys (2017-2019). In each village, 50 individuals from each age groups, including pre-school aged children (2-6 years old), school aged children (7-13 years old), adolescents (14-19 years old), and adults (aged over 20 years old), were randomly selected using household-level random sampling (200 individuals in total).
1,000 girls and women aged 15-65 years old, registered in the MORBID study, were then randomly selected, using simple random sampling, to participate in the cross-sectional MORBID-FGS study. After obtaining written informed consent, participants of the MORBID-FGS study completed a field-validated questionnaire in either English or the national language, administered by a midwife at the local clinic. Questions included socio-demographic characteristics, water contact information, and history of urinary, genital, and SRH signs and symptoms. During the same clinic visit, a midwife captured images of the cervix, fornices and vagina using a EVA MobileODT hand-held colposcope. Additional images were collected on a subgroup of participants using the “Smart-Scope®” hand-held device. Images were evaluated remotely by the study gynaecologis in Malawi and classified as ‘visual-FGS’ if typical lesions were present, and negative if none were observed. In the clinic, midwives also collected a cervicovaginal swab using a Dacron swab which was tested by PCR
Throughout the study, data collection was done electronically through mobile devices and uploaded to a remote server.
Data collected in Nsanje and Chikwawa, Malawi
The type of participants contained within the data, e.g. human population with a specific condition, living in a specific region.
Female genital schistosomiasis, Malawi, Burden of disease.
English
The MORBID-FGS study is part of the larger ‘Morbidity Operational Research for Bilharzia Implementation Decisions’ (MORBID) study, which aims to compare schistosomiasis-associated morbidity between low- and high-level infection prevalence communities.
| Project name | Funder/sponsor | Grant number | LSHTM ethics ID |
| Morbidity Operational Research for Bilharziasis Implementation Decisions for Girls and Women (MORBID-FGS) cross sectional study | Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD) | 19072 |
| Forename | Surname | Faculty / Dept | Institution | Role |
| Olimpia | Lamberti | Faculty of Infectious and Tropical Diseases / Department of Clinical Research | London School of Hygiene & Tropical Medicine | Data Creator |
| Amaya | Bustinduy | Faculty of Infectious and Tropical Diseases / Department of Clinical Research | London School of Hygiene & Tropical Medicine | Data Creator |
| Filename | Description | Access status | Licence |
| Main_Morbid_Data | Data from the parent MORBID study reporting information on S. haematobiumstatus, macrohaematuria, microhaematuria, proteinuria and other morbidities measured in the study population. | Request access for all | Data sharing agreement |
| MORBID_FGS_EVAMobileODT-EVA-data | Dataset reporting visual-FGS status for participants who underwent colposcopy in the clinic using the MobileODT hand-held colposcope | Request access for all | Data sharing agreement |
| MORBID_FGS_SmartScope | Dataset reporting visual-FGS status for the subgroup of participants who underwent colposcopy in the clinic using the SmartScope colposcope | Request access for all | Data sharing agreement |
| MWI_MORBID_FGS_epi_matched | Dataset reporting data after matching information with the parent MORBID study and the MORBID-FGS study components. The dataset reports age, S. haematobium status, and FGS status by EVA MobileODT, SmartScope and PCR | Request access for all | Data sharing agreement |
| MWI_MORBID_FGS_village_level | FGS Village level data. | Request access for all | Data sharing agreement |
| The following tables are contained within the MORBID-FGS data spreadsheet | |||
| Cervicovaginal_Swabs_and_PCR | Dataset reporting ‘molecular-FGS’ status diagnosed by PCR of cervicovaginal swabs collected in clinic | Request access for all | Data sharing agreement |
| EVAMobileODT | Dataset reporting ‘visual-FGS’ status for participants who underwent colposcopy in the clinic using the MobileODT hand-held colposcope | Request access for all | Data sharing agreement |
| FGS_and_Questionnaire_data | MORBID-FGS questionnaire data reporting the sociodemographic characteristics, water contact information, and history of signs and symptoms of women enrolled in the study. | Request access for all | Data sharing agreement |
| FGS_and_Shaem | Individual level FGS data (diagnosed using visual and molecular methods) matched with the S. haematobium data | Request access for all | Data sharing agreement |
| FGS_villageLevel | FGS Village level data. | Request access for all | Data sharing agreement |
| Main_Morbid_data | Data from the parent MORBID study reporting information on S. haematobium status, macrohaematuria, microhaematuria, proteinuria and other morbidities measured in the study population. | Request access for all | Data sharing agreement |
| SmartScope | Dataset reporting ‘visual-FGS’ status for the subgroup of participants who underwent colposcopy in the clinic using the SmartScope colposcope | Request access for all | Data sharing agreement |
| The following tables are contained with the data dictionary spreadsheet | |||
| EVAMobileODT_and_SmartScope_dictionary | Data dictionary for variables reported in the MORBID_FGS_EVAMobileODT-EVA-data file and in the EVAMobileODT tab of the MORBID-FGS file | Open | Creative Commons Attribution (CCBY) |
| MainMorbid_dictionary | Data dictionary for the variables collected as part of the parent MORBID study | Open | Creative Commons Attribution (CCBY) |
| Morbid_FGS_data_Dictionary | Data dictionary for the variables collected as part of the MORBID-FGS study component of the study | Open | Creative Commons Attribution (CCBY) |