Data for: Karachi adult tuberculosis prevalence and child Mycobacterium tuberculosis infection survey, 2018-2019 – Data Codebook

Persistent Identifier

10.17037/DATA.00003788

Description

This record describes two anonymised datasets collected as part of a concurrent adult pulmonary tuberculosis prevalence survey (using digital radiography using CAD4TB and Xpert MTB/RIF Ultra) and child M. tuberculosis infection survey (using QuantiFERON-TB® Gold Plus) using a cluster-based unequal probability random sampling method. The aim was primarily to provide a baseline measure of the burden of adult infectious tuberculosis in Karachi and assess feasibility of conducting QuantiFERON-TB® Gold Plus at scale in children aged 2 to 4 years.

The first survey dataset covers 34,964 adults (aged ≥ 15 years): Each row refers to an adult study participant, indicating their district, cluster, neighbourhood block, age category (mean age for child), sex, CAD4TB score, presence of TB symptoms, eligibility for sputum submission, TB status, previous relevant TB history e.g. contact with TB and TB treatment, and inverse probability and sampling weights.
The second survey dataset covers 2,511 children (aged 2 to 4 years): Each row refers to a child study participant, indicating their district, cluster, neighbourhood block, the overall mean age for child, sex, presence of TB symptoms, QuantiFERON-TB® Gold Plus result, previous relevant TB history e.g. contact with TB and TB treatment, and combined inverse probability and sampling weights.

Data Codebook

The datasets contain the following variables. Please contact the study authors with questions related to the data collection and analysis process.

Variable name	Variable description	Answer code	Answer label	Variable type
district	District
		K	Korangi	string
		W	Karachi West
		C	Karachi Central
		S	Karachi South
prior_acf	Prior ACF Zone
		0	No prior ACF	integer
		1	Prior ACF
ka	Katchi abadi status
		0	No	factor
		1	Yes
cluster_id	Cluster identifier	.	.	string
block_id	Neighbourhood block identifier	.	.	string
participant_id	Participant identifier	.	.	string
age	mean age	3.04	.	numeric
sex	Sex
		1	Female	factor
		2	Male
qft	Quantiferon Gold Plus assay result
		0	Negative	factor
		1	Positive
		2	Indeterminate
tb_contact	Any known contact with person diagnosed with TB within last 2 years
		0	No	integer
		1	Yes
tb_history	Previous history of TB
		0	No	integer
		1	Yes
cough	Cough
		0	No	factor
		1	Yes
fever	Fever
		0	No	factor
		1	Yes
ftt	Failure to thrive
		0	No	factor
		1	Yes
wtloss	Weight loss
		0	No	factor
		1	Yes
dec_playful	Decreased playfulness
		0	No	factor
		1	Yes
totmtb	Number of people identified with micro confirmed PTB in neighbourhood block	0-2	.	integer
median CAD4TB	Median CAD4TB score of all adults screened with CXR in neighbourhood block	0-100	.	integer
totblockpop	Total population of neighbourhood block	.	.	integer
avpop	Average population density within 100 metres of neighbourhood block	.	.	Numeric
overall_wt	Combined inverse probabiity weights and sampling weights	.	.	Numeric