SARS-CoV-2 Seroprevalence in The Gambia dataset – User Guide

Persistent identifier

10.17037/DATA.00003754

Description

A quantitative dataset containing information on COVID seroprevalence in pregnant women, based upon an analysis of samples collected from 803 women between October 2019 – March 2022 in Farafenni, North Bank Region of The Gambia. This is a sub-set of women in the PRECISE Study where pregnant women were recruited to the cohort and followed up during their pregnancy.

Data collection methods

This is an ancillary study of the PRECISE study (Pregnancy Care Integrating Translational Science, Everywhere), in which a pregnancy cohort was recruited in The Gambia, Kenya, and Mozambique, with the collection of extensive sociological and clinical data and biological samples throughout woman's pregnancy, until 6 weeks post-delivery. Samples and data from the PRECISE study were used for this work.

Data access statement

To access the data, requests must be made to the P.I. in The Gambia. The request will be reviewed by both the Gambian Team and the PRECISE Consortium Data and Sample Access Committee, which consists of the leads of all the collaborating units as well as a panel of experts. The committee will review the request based on scientific value and to ensure there is no overlap with existing work. If the study is approved, before data is shared, ethics approval will need to be obtained in both The Gambia and in your host institution as well as Data User Responsibilities Agreements being signed.

Geographic regions

Data collected in Farafenni, a town in the North Bank Region of The Gambia.

Key dates

Data capture was ongoing from July 2019 – March 2022 as part of PRECISE study, a subset of these samples were used for the seroprevalence analysis.  The laboratory analysis took place from 14^th June 2022 – 11^th October.

Quality controls

The data has been cleaned by both the local team and by the co-ordinating unit to identify any outliers.

We measured the specificity of the laboratory test in our study population by analyzing samples collected before the detection of any COVID-19 case outside Wuhan (our Pre-pandemic period covers the period October to December 2019), and were able to confirm the high specificity of this test in our population.

Population

Pregnant women living in the North Bank region of The Gambia.

Privacy

Participant identifiers have been removed from the dataset.

Ethics

Keywords

Antibodies, COVID-19, Pregnancy, Seroprevalence, sub-Saharan Africa, The Gambia

Language of written material

English

Additional information

The PRECISE Network is a consortium led by King’s College London in collaboration with three Clinical Network Hubs (LSHTM at MRC The Gambia, the Aga Khan University, Kenya, and Centro de Investigação em Saúde de Manhiça, Mozambique) and five partnering institutes (Midland State University, Zimbabwe; London School of Hygiene and Tropical Medicine, UK; St Georges University London, UK; University of Oxford, UK; University of British Columbia, Canada). The consortium is governed by the Project Executive Group which is the projects decision making forum. PRECISE Project Executive Group (PEG) consists of the PRECISE Principal Investigator, and the three Clinical Hub Principal Investigators, the Working Group Chairs and the PRECISE management team.

The PRECISE Data and Sample Committee are responsible for the use of data and samples within the network. The PRECISE Data and Access Committee consists of the PRECISE Principal Investigator, and the three Clinical Hub Principal Investigators. In addition, there are 14 additional experts on the panel whose input is requested depending on the data requests that we receive. These include statisticians, epidemiologists, and experts in health geography, child development, maternal health, preterm birth and molecular biology/pathology.

Project information

Creators

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