10.17037/DATA.00003627
Dataset to reproduce the statistical analysis of the baseline prevalence of TB-Infection in the TREATS TB-infection incidence cohort. Each row represents a randomly selected adolescent or young adult of one of the 14 communities that were included in the cohort. TB infection was measured using the QuantiFERON Gold Plus assay. Apart from TB-infection at baseline, the data includes HIV-status, having a household contact on TB-treatment in the past or currently and demographic characteristics.
All household members of randomly selected households were enumerated and eligible adolescents and young adults were invited to a health facility (Zambia) or clinical research site (South Africa) for enrolment. After informed consent. Password-protected tablets were used by trained research assistants to record information on socio-demographic data, TB/HIV history, known TB risk factors, and other characteristics via the administration of a structured questionnaire. Rapid HIV-testing was done at the research site and results recorded using the same tablet. Blood samples were taken for QFT-Plus testing. Results of the QuantiFERON Gold Plus assay were afterwards combined with the questionnaire data using the unique (barcoded) identifier of the participant.
| Variable name | Variable label | Answer label | Answer code | Variable type |
| country | Country of study | String | ||
| South Africa | SA | |||
| Zambia | Z | |||
| roomshare | Number of people sharing a room | Numeric | ||
| no sharing | 0 | |||
| Share with one other person | 1 | |||
| Share with two other persons | 2 | |||
| Share with three other persons | 3 | |||
| Share with four other persons | 4 | |||
| Share with 5 or more other persons | 5 | |||
| smoking | Smoking status | |||
| No | 0 | |||
| Yes, but I have stopped | 1 | |||
| Yes, I still smoke | 2 | |||
| community | Community of residence | String | ||
| SA14 | ||||
| SA15 | ||||
| SA16 | ||||
| SA17 | ||||
| SA19 | ||||
| SA21 | ||||
| Z10 | ||||
| Z12 | ||||
| Z2 | ||||
| Z3 | ||||
| Z4 | ||||
| Z5 | ||||
| Z7 | ||||
| Z8 | ||||
| sex | Sex of individual | Numeric | ||
| Male | 1 | |||
| Female | 2 | |||
| agegroup | Age group of individual | Numeric | ||
| 15 - 16 years | 1 | |||
| 17 - 18 years | 2 | |||
| 19 - 20 years | 3 | |||
| 21 - 22 years | 4 | |||
| 23 - 24 years | 5 | |||
| qft | Outcome of the QuantiFERON-TB Gold Plus assay using the manufacturer’s cut off of 0.35IU/ml | Numeric | ||
| Negative | 0 | |||
| Positive | 1 | |||
| hhdens | Household density category – the number of people in the household divided by number of rooms in the house | Numeric | ||
| Less than 1.2 | 1 | |||
| Greater than or equal to 1.2 and less than 1.67; | 2 | |||
| Greater than or equal to 1.67 and less than 2.33; | 3 | |||
| Greater than or equal to 2.33 | 4 | |||
| hiv | HIV status | Numeric | ||
| HIV negative | 0 | |||
| HIV positive | 1 | |||
| hhcontact | TB treatment of household contact | Numeric | ||
| No contact | 0 | |||
| Previous | 1 | |||
| Currently only | 2 | |||
| Both previous and current | 3 | |||
| alcohol | Alcohol use | Numeric | ||
| Never | 0 | |||
| Monthly | 1 | |||
| 2-4 times a month | 2 | |||
| 5 or more times a month | 3 | |||
| qfttb1 | Outcome of the QuantiFERON-TB Gold Plus assay using the manufacturer’s cut off of 0.35IU/ml for only the tb1 antigen tube | Numeric | ||
| Negative | 0 | |||
| Positive | 1 | |||
| qfttb2 | Outcome of the QuantiFERON-TB Gold Plus assay using the manufacturer’s cut off of 0.35IU/ml for only the tb2 antigen tube | Numeric | ||
| Negative | 0 | |||
| Positive | 1 | |||
| ifn_diff06 | Antigen tube differential (TB2-TB1)>0.6IU/ml | Numeric | ||
| No | 0 | |||
| Yes | 1 |