Data for: PrEP preference among adolescent boys and young men in three sub-Saharan African countries - User Guide

Permanent identifier

10.17037/DATA.00003232

Description

A quantitative and qualitative dataset collected as part of a Combined HIV Adolescent Prevention Study (CHAPS), a joint African-European HIV prevention collaboration running in South Africa, Uganda, and Zimbabwe, focusing on young adults (13-24 years old) between April and November 2019. It includes data for young people aged 13-24 years, who were sexually active (engaged in sexual intercourse in the past six months), willing to undergo HIV testing, and had no history of psychological/psychiatric disorder. Data included PrEP preferences, reasons for preference, age, household details, frequency of sex in last month and hours of premeditation before sex.

Data collection methods

The quantitative data were collected on tablets using Open Data Kit software, by trained research assistants.

Qualitative interviews were conducted by experienced social science researchers, who conducted group discussions (GDs) and In-Depth Interviews (IDIs), using a semi-structured topic guide, in a secure and private location that was comfortable for the interviewer and the interviewee.

Data analysis and preparation

We used STATA version 15 for cleaning and analysis of quantitative data. Participant socio-demographic, sexual risk behaviour, and other variables were summarized using means with standard deviations or medians with interquartile range for continuous variables and frequencies with percentages for categorical variables, all stratified by country.

A thematic analysis approach was used to identify, analyse, and interpret patterns of meaning (‘themes’) within the qualitative data. To attain this analysis, data familiarization was conducted, the researchers at each study site read the transcripts several times and made notes of key ideas and recurrent codes.

Geographic regions

Purposive community-based sampling was used to recruit young people aged 13-24 years in four settings: Johannesburg and Cape Town in South Africa, Wakiso in Uganda, and Chitungwiza in Zimbabwe. In South Africa and Zimbabwe, participants were recruited from community groups, schools, churches, bars, taxi ranks, and other public meeting places, with CHAPS fieldworkers providing an overview of the study to establish initial interest. In Uganda, participants were recruited at fish landing sites, with information on the study being provided through local leaders, Village Health Teams, and project mobilisers.

Key dates

Data collected between April and November 2019.

Quality controls

Standardised CRFs were used to collect and record all quantitative data. Project staff were trained in principles of ICH-GCP. Project staff were also trained on the study database, completion of CRFs and data quality control procedures. The ODK database was designed to quality control the data at entry have logic checks such as validation of double data entry discrepancy checks through discrepancy note alerts, key missing data, and checking data consistency within individual CRFs.

The data was reviewed, cleaned and managed by data managers using Stata data quality checking do files. Queries were routinely identified and forwarded to the study sites for resolution. Once raised to the sites, their resolution progress was monitored.

Population

We recruited individuals aged 13–24 years of age, sexually active (engaged in sexual intercourse in the past six months), willing to undergo HIV testing, and had no history of psychological/psychiatric disorder.

Privacy

At the site, CRFs and source documents were kept in a secure central location. All computers were password controlled. All data was collected in a pseudo-anonymised format with every participant having a participant ID. No names were collected in the study database.

Ethics

Keywords

PrEP, pre-exposure prophylaxis, HIV, AIDS, adolescent, Sub-Saharan Africa

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Project information

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