https://doi.org/10.17037/DATA.00003123
Joy, E (Principal Investigator), Sturgess, J (Data Manager) and Allen, E (Co-Investigator)
The Alleviating Hidden Hunger with Agronomy (AHHA) Malawi trial sought to test the efficacy of alleviating selenium deficiency through consumption of maize flour enriched with fertilizers in a Malawi-based context. The anonymised dataset contains outcome results of the investigation.
This dataset is an update to the dataset published at 10.17037/DATA.00001993. It contains 12 additional measurements (FER_base_ugL, sTFR_base_mgL, BodyIronStores_base_mgkgbodyweig, RBP_base_RE_umolL, CRP_base_mgL, AGP_base_gL, FER_end_ugL, sTFR_end_mgL, BodyIronStores_end_mgkgbodyweig, RBP_end_RE_umolL, CRP_end_mgL, AGP_end_gL).
Experiment: Field Intervention
Participant demographic information, morbidity outcomes and dietary information were captured through interviewer-administered questionnaires. Blood haemoglobin concentrations were measured in the field by trained Research Assistants. Serum selenium concentrations were measured by ICPMS.
Selenium, Agronomic Biofortification, Maize
| Project title | Funder name | Grant number | Notes |
| Can dietary mineral deficiencies in a rural Malawi population be improved through the consumption of maize flour enriched using micronutrient fertilizers? | Bill & Melinda Gates Foundation | INV-009129 | ISRCTN85899451 https://doi.org/10.1186/ISRCTN85899451 |
The following variables are contained within the AHHA-Malawi-trial-results-dataset. The value 'NA' represents 'Not Applicable'.
| Variable name | Variable label | Answer code | Answer label |
| participant-label | Unique participant ID - unlinked from main dataset to ensure anonymity | ||
| group | Group type | ||
| 0 | Control | ||
| 1 | Intervention | ||
| hh | household ID - unlinked from main dataset to ensure anonymity | ||
| adult_child | Demographic group | ||
| Adult | Adult | ||
| Child | Child | ||
| age_group | Age group | ||
| 1 | 5-10 years | ||
| 2 | 20-29 years | ||
| 3 | 30-39 years | ||
| 4 | 40 years or over | ||
| se_base | plasma selenium concentration at baseline, µg/L | ||
| se_end | plasma selenium concentration at endline, µg/L | ||
| hb_base | whole blood haemoglobin concentration at baseline, g/dL | ||
| hb_end | whole blood haemoglobin concentration at endline, g/dL | ||
| diarrhoea | Has the participant suffered diarrhoea in the past two weeks? Diarrhoea is defined as 3 or more watery stools over a 24 hour period | ||
| Yes | Yes | ||
| No | No | ||
| Not sure | Not sure | ||
| NULL | Not completed | ||
| maxstools | What is the maximum number of stools in a 24 h period during the diarrhoeal episode? | ||
| diarrhoea_prolonged | Did the diarrhoea last between 7-13 days? | ||
| Yes | Yes | ||
| No | No | ||
| Not sure | Not sure | ||
| NULL | Not completed | ||
| diarrhoea_blood | Did the participant have any blood in their stools? | ||
| Yes | Yes | ||
| No | No | ||
| NULL | Not completed | ||
| fever | Has the participant suffered fever in the past 2 weeks? Fever is defined as a high temperature | ||
| Fever for 1–2 days | Fever for 1–2 days | ||
| Fever for 3–4 days | Fever for 3–4 days | ||
| Fever for 5+ days | Fever for 5+ days | ||
| No fever | No fever | ||
| Not sure/would rather not say | Not sure/would rather not say | ||
| NULL | Not completed | ||
| vomiting | Has the participant suffered vomiting in the past 2 weeks? | ||
| Vomiting for 1–2 days | Vomiting for 1–2 days | ||
| Vomiting for 3–4 days | Vomiting for 3–4 days | ||
| Not sure/would rather not say | Not sure/would rather not say | ||
| No vomiting | No vomiting | ||
| NULL | Not completed | ||
| cough | Has the participant had an illness with a cough at any time in the last 2 weeks? | ||
| Yes | Yes | ||
| No | No | ||
| Not sure | Not sure | ||
| Would rather not say | Would rather not say | ||
| NULL | Not completed | ||
| breathing | Has the participant had fast, short, rapid breaths or difficulty breathing at any time in the last 2 weeks? | ||
| Yes | Yes | ||
| No | No | ||
| Not sure | Not sure | ||
| Would rather not say | Would rather not say | ||
| NULL | Not completed | ||
| chest | Was the fast or difficult breathing due to a problem in the chest or to a blocked or runny nose? | ||
| Both | Both | ||
| Chest only | Chest only | ||
| Don't know/would rather not say | Don't know/would rather not say | ||
| Nose only | Nose only | ||
| Other (specify) | Other | ||
| NULL | Not completed | ||
| se-intake-base-visit1 | dietary selenium intake at baseline, µg/day | ||
| se-intake-base-repeat | dietary selenium intake at baseline at repeat visit for randomly-selected subset, µg/day | ||
| se-intake-end | dietary selenium intake at endline, µg/day | ||
| se-intake-end-repeat | dietary selenium intake at endline at repeat visit for randomly-selected subset, µg/day | ||
| pregnant-end | self-reported pregnancy status | ||
| y | Yes | ||
| NULL | Not completed | ||
| lactating-end | self-reported lactation status | ||
| y | Yes | ||
| NULL | Not completed | ||
| FER_base_ugL | Serum ferritin concentration at baseline | ||
| sTFR_base_mgL | Serum transferrin receptor concentration at baseline | ||
| BodyIronStores_base_mgkgbodyweig | Body iron stores | ||
| RBP_base_RE_umolL | Retinol binding protein at baseline | ||
| CRP_base_mgL | C-reactive protein concentration at baseline | ||
| AGP_base_gL | Αlpha-1-acid glycoprotein concentration at baseline | ||
| FER_end_ugL | Serum ferritin concentration at endline | ||
| sTFR_end_mgL | Serum transferrin receptor concentration at endline | ||
| BodyIronStores_end_mgkgbodyweig | Body iron stores | ||
| RBP_end_RE_umolL | Retinol binding protein at endline | ||
| CRP_end_mgL | C-reactive protein concentration at endline | ||
| AGP_end_gL | Αlpha-1-acid glycoprotein concentration at endline |