Entebbe Mother and Baby Study – Data at one year – User Guide

Persistent identifier

10.17037/DATA.128

Description

Dataset and supporting documentation collected as part of the Entebbe Mother and Baby Study (EMaBS), a clinical trial that investigated potential benefits of treating worm infections during pregnancy and early childhood. The dataset contains variables collected from mothers (at registration) and infants (when the child was one-year of age), including maternal age, education, parity and infection status (malaria, S. mansoni, hookworm, filariasis), and infant sex and immune responses (to HiB, diphtheria, Hepatitis B, pertussis, FHA, pertactin).

Data collection methods

Data was collected as part of a randomised control trial, ISRCTN32849447. Pregnant women who enrolled were randomised twice in this 2x2 factorial trial of albendazole and praziquantel to investigate the effect of maternal worms on infant vaccine response in urban Uganda.

Data analysis and preparation

All personal identifiable variables have been removed, including maternal date of birth, infant date of birth, home location and dates of vaccinations.

Geographic regions

Entebbe, Uganda

Key dates

Mothers were enrolled between April 2003 and November 2005. Data from infants was collected between April 2004 and May 2007.

Quality controls

Test results reviewed and anomalous results addressed by lab team.

Population

Mothers and children enrolled in the Entebbe Mother and Baby trial.

Privacy

This dataset contains no identifiable data.

Ethics

Ethical consent was granted for the original trial and for subsequent analysis from the following research ethics committees.

Keywords

Pregnancy, vaccine, albendazole, praziquantel, schistosomiasis, hookworm, HiB, Diphtheria, Hepatitis B, Pertussis FHA, Pertactin

Language of written material

English

Project information

Associated roles

File description