Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial – User Guide

Persistent identifier

10.17037/DATA.117

Description

This study was done to determine the effectiveness of Seasonal Malaria Chemoprevention in Senegalese children up to 10 years of age using a stepped-wedge design. Outcomes included mortality, malaria cases treated as outpatients, severe malaria, and the prevalence of parasitaemia and anaemia, and adverse drug reactions. 54 health posts were randomized. 9 started implementation of SMC in 2008, 18 in 2009, and a further 18 in 2010, with 9 remaining as controls. In the first year of implementation SMC was delivered to children aged 3-59 months, the age range was then extended for the latter two years of the study to include children up to 10 years of age.

Keywords

Seasonal Malaria Chemoprevention, Malaria, stepped-wedge trial

Key dates

Population

Human population

Privacy

Personal data has been redacted.

Ethics

Ethics approval obtained from London School of Hygiene & Tropical Medicine, Universite Cheikh Anta Diop, Dakar, and Institut de Recherche pur le Developpement, Dakar

Project information

Project title Funder/sponsor Grant number
Effectiveness of Seasonal Malaria Chemoprevention in children under 10 years of age in Senegal: a stepped-wedge cluster-randomized trial Bill & Melinda Gates Foundation 40099

Language of written material

English

Participating Institutions:

Creators

Forename Surname Faculty / Dept Institution Role
Paul Milligan Epidemiology & Population Health / Infectious Disease Epidemiology London School of Hygiene & Tropical Medicine Data Creator

Associated roles

Forename Surname Faculty / Dept Institution Role
Badara Cisse   London School of Hygiene & Tropical Medicine Project Leader
Oumar Gaye     Project Leader
Elhadji Ba   London School of Hygiene & Tropical Medicine Project Leader
Jean Louis NDiaye     Project Leader
Paul Snell Epidemiology & Population Health / Infectious Disease Epidemiology London School of Hygiene & Tropical Medicine Data Manager

File description

Filename Description Access status Licence
malaria_aggregated_data Malaria aggregated data Controlled access Data sharing agreement
mortality_aggregated_data Mortality aggregated data Controlled access Data sharing agreement
mal.do Basic STATA DO file for aggregated Malaria dataset Controlled access As above
mortality.do Basic STATA DO file for aggregated Mortality dataset Controlled access As above
survey_2008 French language data collection forms for 2008 study Controlled access As above
survey_2009 French language data collection forms for 2009 study Controlled access As above
survey_2010 French language data collection forms for 2010 study Controlled access As above
0117-Codebook Data codebook for Aggregated Mortality and Malaria datasets Open Creative Commons Attribution (CCBY)
0117-UserGuide User guide for Mortality and Malaria datasets (this document) Open Creative Commons Attribution (CCBY)

The following datasets were also collected by the study. Please direct questions to the study team.

Filename Description
survey_dataset_2008.xls Dataset containing individual-level information for the cross-sectional survey of SMC coverage, parasitaemia and haemoglobin performed in 2008
survey_dataset_2009.xls Dataset containing individual-level information for the cross-sectional survey of SMC coverage, parasitaemia and haemoglobin performed in 2009
survey_dataset_2010.xls Dataset containing individual-level information for the cross-sectional survey of SMC coverage, parasitaemia and haemoglobin performed in 2010
survey_2008.doc French language data collection forms for 2008 study
survey_2009.doc French language data collection forms for 2009 study
survey_2010.doc French language data collection forms for 2010 study