https://doi.org/10.17037/DATA.00002753
The SPRING-ELS sub-study of the SPRING cluster randomised controlled trial included 1304 children that had adversity exposure assessment conducted at 12 months of age. Hair cortisol concentration was assessed in 845 of them at this time. As part of the REACH follow-up study, 1124 children (of the 1304 with adversity assessments) were followed-up at three years of age to assess height, weight and cognition using the Developmental Assessment on an E-Platform (DEEP) tool. 607 children had hair cortisol assessments available in this subset.
The anonymised dataset contains information on 1124 children at three years of age that were collected as part of the REACH follow-up study. This includes cluster codes, trial arm allocation, height, weight, cognition and other scores assigned to each child.
There were missing data for some variables including log_hcc and the adversity variables. This is because not all assessments were completed with all children - this is described further in the paper. In this paper, missing data were accounted for using multiple imputation with chained equations, including all explanatory and outcome variables in each analysis, using 30 imputations.
| Variable name | Variable description | Answer code | Answer label | Variable Type |
| ID | Child ID – Randomly assigned | 1 - 1124 | Numeric | |
| clusternum | Cluster code – Randomly assigned | 1 - 26 | Numeric | |
| XYstatus | Trial Arm (blinded until SPRING trial results published). Number 0 or 1 representing trial intervention or control arm. | Numeric | ||
| 0 | Trial intervention | |||
| 1 | Control arm | |||
| sex01 | Sex of child | Numeric | ||
| 0 | Female | |||
| 1 | Male | |||
| loghcc | Log of hair cortisol concentration in log picograms per milligram of hair | 0 - 5 | Numeric | |
| ageatvisit36m | Age at which children were assessed at the 36 month visit | |||
| m36_haz | Height for age z-score at 36 month visit | Numeric | ||
| m36_waz | Weight for age z-score at 36 month visit | Numeric | ||
| deepscore | Deep cognitive assessment score at 36 month visit | Numeric | ||
| scoreadv_ses | Adversity – socioeconomic scale score | Numeric | ||
| scoreadv_parents | Adversity – parent scale score | Numeric | ||
| scoreadv_relat | Adversity – relationship scale score | Numeric | ||
| scoreadv_child | Adversity – child scale score | Numeric | ||
| totalscore | Adversity – total score | Numeric | ||
| deepzscore | Deep cognitive assessment score at 36 month visit – z-score | Numeric |
early life adversities, adversity exposure assessment, child development, childhood adversity
English
The SPRING Cluster Randomised Controlled Trial (SPRING) is described at https://clinicaltrials.gov/ct2/show/NCT02059863.
| Project name | Funder/sponsor | Grant number | Other information |
| SPRING Cluster Randomised Controlled Trial (SPRING) | Wellcome Trust | 1075718/Z/15/Z | - |
| Forename | Surname | Faculty / Institution | Role |
| Debarati | Mukherjee | Indian Institute of Public Health-Hyderabad | Data collection, analysis and writing |
| Sunil | Bhopal |
Population Health Sciences Institute, Newcastle University, United Kingdom Maternal & Child Health Intervention Research Group, Department of Population Health, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, United Kingdom |
Data collection, analysis, writing |
| Supriya | Bhavnani | Sangath, India | Data collection, analysis, writing |
| Kamal Kant | Sharma | Sangath, India | Data collection, analysis, writing |
| Reetabrata | Roy |
Maternal & Child Health Intervention Research Group, Department of Population Health, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, United Kingdom Sangath, New Delhi, India |
Data collection, analysis, writing |
| Gauri | Divan | Sangath, New Delhi, India | Data collection, analysis, writing |
| Siddhartha | Mandal | Sangath, New Delhi, India | Data collection, analysis, writing |
| Betty | Kirkwood | Maternal & Child Health Intervention Research Group, Department of Population Health, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, United Kingdom | Data collection, analysis, writing |
| Vikram | Patel |
Sangath, New Delhi, India Harvard T H Chan School of Public Health, United States |
Data collection, analysis, writing |
Correspondence to: Professor Vikram Patel: Email - vikram_patel@hms.harvard.edu
| Filename | Description | File format | Access status | Licence |
| SPRING-REACH_dataset | Anonymised dataset containing information on 1124 children at three years of age collected as part of the REACH follow-up study | Comma Separated Values (.csv) | Open | Creative Commons Attribution (CC BY) |
| Adversity_growth_development | Extended Data (Adversity Growth Development 1 June 2021): Document contains Figure 1, Table 1, Table 2, and Table 3 associated with manuscript | MS Word (.docx), PDF/A (.pdf) | Open | Creative Commons Attribution (CC BY) |
| 2753_UserGuide | User guide for dataset (this document) | Open | Creative Commons Attribution (CC BY) |