https://doi.org/10.17037/DATA.00002282
A tabular dataset that contains information used to investigate an association between cervical dysplasia and female genital schistosomiasis diagnosed by genital PCR in Zambian women, aged 18-31. Women were recruited from the Bilharzia and HIV (BILHIV) study in Zambia, which was a community-based study comparing genital self-sampling to provider obtained cervicovaginal-lavage for the diagnosis of FGS in women aged 18-31. FGS was defined as positive Schistosoma DNA from any genital PCR. Urogenital schistosomiasis diagnostics included urine circulating anodic antigen, urine microscopy and portable colposcopy. Participants were offered cervical cancer screening using VIA at a local hospital. Associations of PCR confirmed FGS and other diagnostics with VIA positivity were assessed using multivariable logistic regression.
Names and other direct identifiers have been removed prior to submission. Participant age and other information that may be used to identify participants in combination with other data has been placed into broad categories to reduce the disclosure risk. However, there remain a number of unique measurements. These values will be removed when preparing data for access.
The cross-sectional bilharzia and HIV (BILHIV) study was nested in HPTN 071 (PopART), a cluster randomized trial to measure the impact of an HIV-1 combination prevention package. The same ethics approvals apply.
| Codebook variable | Data type | Description | Information | Response code | Response label |
| id_bilhiv | Integer | Anonymised ID number | Anonymised ID number | ||
| hivstatus | Binary | Self-reported HIV status from screening book | Provided in clinical records at cervical cancer screening centre | ||
| 0 | HIV negative | ||||
| 1 | HIV positive | ||||
| viaresult | Binary | VIA status | Provided in clinical records at cervical cancer screening centre | ||
| 0 | VIA negative | ||||
| 1 | VIA positive | ||||
| treatment_yn | Binary | Treatment for VIA positivity | Provided in clinical records at cervical cancer screening centre | ||
| 0 | No treatment received | ||||
| 1 | Treatment received | ||||
| treatment_text | Text | Treatment type given for VIA positivity | Provided in clinical records at cervical cancer screening centre | ||
| district | Integer | District in which participant lives | Is the patient being recruited in community A or Community B? | ||
| 1 | Community A | ||||
| 2 | Community B | ||||
| agegp4 | Integer | Participant age group | How old are you? | ||
| 1 | 18-24 | ||||
| 2 | 25-31 | ||||
| edu3 | Integer | Highest education achieved | What is your level of education? | ||
| 1 | None/any primary | ||||
| 2 | Any secondary | ||||
| 3 | Trade/degree | ||||
| marst1 | Integer | Marital status | What is your marital status? | ||
| 1 | Single | ||||
| 2 | Married or living as married | ||||
| 3 | Divorced/widowed/separated | ||||
| dememp | Binary | Currently employed | Are you currently working? | ||
| 0 | Currently unemployed | ||||
| 1 | Currently employed | ||||
| everpreg | Binary | Ever previously been pregnant | Have you ever been pregnant? | ||
| 0 | Never pregnant | ||||
| 1 | Previously pregnant | ||||
| hadbilz | Binary | Previously had schistosomiasis | Have you ever had bilharzia? | ||
| 0 | No | ||||
| 1 | Yes | ||||
| 2 | No answer or refused | ||||
| txbilz | Binary | Previous treatment for schistosomiasis | Have you ever received treatment for bilharzia? | ||
| 0 | No | ||||
| 1 | Yes | ||||
| 2 | No answer or refused | ||||
| contrano | Binary | No contraception | Are you currently not using contraception? | ||
| 0 | Some form of contraception | ||||
| 1 | No contraception | ||||
| contracon | Binary | Condoms | Do you use condoms for contraception? | ||
| 0 | No condom use | ||||
| 1 | Condom use | ||||
| micropos | Binary | Urine microscopy for Schistosoma haematobium ova | Laboratory result | ||
| 0 | Negative | ||||
| 1 | Positive | ||||
| CAAbinary | Binary | Urine CAA positive/negative | Laboratory result | ||
| 0 | Negative | ||||
| 1 | Positive | ||||
| anypcr1 | Binary | Any genital sample S. haematobium PCR positive/negative | Study generated variable | ||
| 0 | FGS not detected | ||||
| 1 | Any genital PCR positive | ||||
| microcaapos | Binary | Composit of urine microscopy and CAA | Study generated variable | ||
| 0 | Both urine microscopy and CAA negative | ||||
| 1 | Either urine microscopy or CAA positive | ||||
| fgs1 | Binary | Presence of FGS by visual inspection | Are sandy patches (sandy or homogenous yellow) or abnormal vessels visualized on portable colposcopy? | ||
| 0 | No FGS on visual inspection | ||||
| 1 | Signs of FGS present - sandy patchy, rubbery papule or abnormal blood vessels | ||||
| 999 | Not able to evaluate (missing or technical issue with image or image file) | ||||
| hivstatuspopartstart | Binary | HIV status at start of PopART trial | What was the HIV-1 status of the participant at the start of PopART? | ||
| 0 | HIV negative | ||||
| 1 | HIV positive | ||||
| hivstatuspopartend | Binary | HIV status at end of PopART trial | What was the HIV-1 status of the participant at the end of PopART? | ||
| 0 | HIV negative | ||||
| 1 | HIV positive | ||||
| Null | Not recorded | ||||
| seroconv | Binary | Seroconversion during PopART | Did the participant seroconvert to HIV-1 positive during PopART? | ||
| 0 | No seroconversion | ||||
| 1 | Seroconversion during PopART | ||||
| Null | Not recorded |