https://doi.org/10.17037/DATA.00002110
Ioana-Diana Olaru
A quantitative dataset collected as part of the ARGUS study that presents the clinical and bacteriological outcomes of 168 participants who had a positive urine culture at baseline and underwent a follow-up visit. Adult participants were recruited from primary healthcare facilities in Harare, Zimbabwe. Data was collected from participant interviews using electronic CRFs. Laboratory results were recorded using specifically designed Case Report Forms (CRFs).
Antimicrobial resistance, Urinary tract infections, Clinical outcomes, Bacteriological outcomes
| Project name | Funder | Grant number |
| ARGUS | Wellcome | 203905/Z/16/Z |
Olaru, et al (2020). Antimicrobial Resistance in Gram-negative bacteria from Urinary Specimens: a study of prevalence, risk factors and molecular mechanisms of resistance (ARGUS) in Zimbabwe - a study protocol. Wellcome open research, 5. 140-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.15977.1
The following variables are contained within the ARGUS outcome dataset.
| Variable name | Variable label | Answer label | Answer code | Variable type |
| sex | Sex | Categorical | ||
| Male | 1 | |||
| Female | 2 | |||
| age | Age group | Age groups of 10 years | Categorical | |
| education | Highest level of education completed | Categorical | ||
| 0 | none | |||
| 1 | primary | |||
| 2 | secondary | |||
| 3 | tertiary | |||
| 9 | not answered | |||
| dur_sx | Duration of symptoms prior to presentation (days) | Numerical | ||
| cur_abx | Antibiotics prescribed at the clinic | Categorical | ||
| cur_abx_oth | Other antibiotics prescribed at the clinic | String (free text) | ||
| pregnant | Current pregnancy | Categorical | ||
| No | 0 | |||
| Yes | 1 | |||
| Unknown | 9 | |||
| Not applicable | Missing | |||
| culture_result | Urine culture result at baseline | Restricted to >10^5 for this analysis | Categorical | |
| culture_id | Bacteria isolated at baseline | Categorical | ||
| ampicillin | Amoxicillin/ ampicillin susceptibility according to AST at baseline | Categorical | ||
| Sensitive | 0 | |||
| Resistant | 1 | |||
| Not applicable/not done | Missing | |||
| ciprofloxacin | Ciprofloxacin susceptibility according to AST at baseline | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable/ not done | |||
| ceftriaxone | Ceftriaxone susceptibility according to AST at baseline | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable/ not done | |||
| nitrofurantoin | Nitrofurantoin susceptibility according to AST at baseline | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable/ not done | |||
| f1fu_sx | Symptoms at the follow-up visit | Categorical | ||
| 1 | Yes, completely | |||
| 2 | Yes, partially | |||
| 3 | No, symptoms are present at the same intensity | |||
| 4 | No, symptoms are present and worse | |||
| 5 | 5-Symptoms initially resolved, then reappeared | |||
| f1_days_res | Number of days until resolution of symptoms (only if symptoms resolved) | Numerical | ||
| f1abx_take | Did you take the antibiotics prescribed at the baseline visit | Categorical | ||
| f1abxtake_dih | Did you take the antibiotics prescribed (derived from previous) | Categorical | ||
| 0 | Did not take antibiotics/ not prescribed | |||
| 1 | Took antibiotics | |||
| fu_culture_result | Follow up urine culture result | Categorical | ||
| >10^5 | Bacterial growth of >105 CFU/mL | |||
| 10^4-10^5 | CFU/mL Bacterial growth of 104-105 | |||
| 10^3-10^4 | Bacterial growth of 103-104 CFU/mL | |||
| Contamination | culture was contaminated | |||
| No growth | culture negative | |||
| fu_culture_id | Bacteria identified from the urine culture at follow up | Categorical | ||
| fu_ampicillin | Amoxicillin/ ampicillin susceptibility according to AST at follow up | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable / not done | |||
| fu_ciprofloxacin | Ciprofloxacin susceptibility according to AST at follow up | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable / not done | |||
| fu_ceftriaxone | Ceftriaxone susceptibility according to AST at follow up | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable / not done | |||
| fu_nitrofurantoin | Nitrofurantoin susceptibility according to AST at follow up | Categorical | ||
| 0 | Sensitive | |||
| 1 | Resistant | |||
| Missing | Not applicable / not done | |||
| apptx | Did the patient receive appropriate treatment (derived variable from current treatment and AST result) | |||
| dur_fu1 | Time to follow up visit | Numerical | ||
| f1sx_dih | Presence/absence of symptoms at follow up (derived from the variable on symptoms at follow up) | Categorical | ||
| 0 | No | |||
| 1 | Yes | |||
| fuc_dih | Culture result at follow up (derived from the culture result at follow up) | Categorical | ||
| 0 | Culture positive/ contaminated | |||
| 1 | Culture negative |